• University of California, Berkeley, USA
  October 2001 - August 2005: Postdoctoral work, supervisor: Prof. Dr. J. Kuriyan

• The Rockefeller University, New York, USA
  July 2001 - October 2001: Postdoctoral work, supervisor: Prof. Dr. J. Kuriyan

• Max-Planck-Institute of Biochemistry, Martinsried, Germany
  November 1997 - June 2001: PhD dissertation, supervisor: Prof. Dr. F. U. Hartl (summa cum laude)

• University of Cologne, Germany
  October 1992 - October 1997: Diploma in Biology

• Kaiserin-Theophanu-Gymnasium, Cologne, Germany
  August 1983 - May 1992: Abitur
  
  

Research and Professional Experience:

• Cornell University, Ithaca, USA
  September 2005 - present: Assistant professor at the College of Veterinary Medicine (Molecular Medicine)

• University of California, Berkeley, USA
  October 2001 - August 2005: Postdoctoral work, supervisor: Prof. Dr. J. Kuriyan
  Subject: Allosteric activation and autoinhibition of the Ras-specific nucleotide exchange factor Son of Seveneless.

• The Rockefeller University, New York, USA
  July 2001 - October 2001: Postdoctoral work, supervisor: Prof. Dr. J. Kuriyan
  Subject: Structure/function analysis of inhibition mechanisms in receptor tyrosine kinases.

• Max-Planck-Institute of Biochemistry, Martinsried, Germany
  November 1997 - June 2001: PhD dissertation, supervisor: Prof. Dr. F. U. Hartl
  Subjects:
  1. Structure/function analysis of the Hsp70 co-chaperone Bag-1.
  2. Characterization of a monocyte/macrophage-specific receptor for heat shock protein 70.

• University of Cologne, Germany
  January 1997 - October 1997: Diploma thesis, supervisors: Prof. Dr. M. Paulsson and Dr. M. Aumailley
  Subject: Biochemical analysis of different cell adhesion complexes.
  
  

Teaching Experience:

• Cornell University, Ithaca, USA
  November 2006: A Genomics Approach to Studying Life, guest lecturer (Structural Genomics), Course instructor: John Schimenti, Bio GM 400.
  
  November 2006: Block II (Cell Biology and genetics), Veterinary Medicine Foundation Course, lecturer and small group discussion leader.
  
  March 2006: Regulation of Cell Proliferation, Senescence, and Death, guest lecturer (Growth factor and Ras signaling), Course instructor: Siu Sylvia Lee, Bio BM 437 (4370).
  
  September 2005: Frontiers in Biophysics (09/17/2005), one-day biophysics symposium, presentations from members of the field of biophysics, BIO G 431 (4310).

• University of California, Berkeley Berkeley, USA
  January 2002 - March 2004: Supervision of three PhD rotation students (Molecular and Cell Biology PhD program) in the department of Prof. Dr. J. Kuriyan.

• Max-Planck-Institute of Biochemistry Martinsried, Germany
  October 1999 - June 2000: Supervision of a technical assistant in the department of Prof. Dr. F. U. Hartl.
  
  

Honers and Awards:

• Robert N. Noyce Assistant Professor in Life Science and Technology
  June 2006 - present

• Leukemia & Lymphoma Society Fellowship (Career Development Program)
  July 2002 - July 2005: The Leukemia & Lymphoma Society, USA

• Young Investigator Research Award 2002
  Max-Planck-Institute of Biochemistry, Germany
  
  

Services:

• Veterinary Library Committee
  Februar 2006 - present

• Seminar Coordinator at the Department of Molecular Medicine
  June 2006 - present

• Executive Committee member, Graduate Field of Pharmacology
  September 2006 - present
  
  

Societies:

• German Society for Biochemistry and Molecular Biology (GBM)
• Biophysical Society
• The Protein Society
  
  

List of Publications:

• Freedman, T.S.*, Sondermann, H.*, Friedland, G., Kortemme, T., Bar-Sagi, D., Marqusee, S., and Kuriyan, J. (2006). A Ras-induced conformational switch in the Ras activator Son of sevenless. Proc Natl Acad Sci U S A 103(45):16692-16697.
  (*These authors contributed equally to this work.)
• Boykevisch, S., Zhao, C., Sondermann, H., Philippidou, P., Halegoua, S., Kuriyan, J., and Bar-Sagi, D. (2006). Regulation of Ras signaling dynamics by Sos-mediated positive feedback. Current Biology 16(21): 2173-2179.
• Pirruccello, M., Sondermann, H., Pelton, J.G., Pellicena, P., Hoelz, A., Chernoff, J., Wemmer, D.E., and Kuriyan, J. (2006). A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases. J Mol Biol 361: 312-326.
• Sondermann, H., Nagar, B., Bar-Sagi, D., and Kuriyan, J. (2005). Computational docking and solution X-ray scattering predict a membrane-interacting role for the histone domain of the Ras-activator Son of Sevenless. Proc Natl Acad Sci U S A 102(46):16632-16637.
• Sondermann, H., and Kuriyan, J. (2005). C2 can do it, too. Cell 121:158-160 (Preview).
• Mao, X., Ren, Z., Parker, G.N., Sondermann, H., Pastorello, M.A., Wang, W., McMurray, J.S., Demeler, B., Darnell, J.E.Jr., and Chen, X. (2005). Structural bases of unphosphorylated STAT1 association and receptor binding. Molecular Cell 17(6):761-771.
• Sondermann, H.*, Zhao, C.*, and Bar-Sagi, D. (2005). Analysis of Ras:RasGEF Interactions by Phage Display and Static Multi Angle Light Scattering. Methods 37(2):197-202.
  (*These authors contributed equally to this work.)
• Sondermann, H.*, Soisson, S.M.*, Boykevisch, S., Yang, S.-S., Bar-Sagi, D., and Kuriyan, J. (2004). Structural analysis of autoinhibition in the Ras activator Son of Sevenless. Cell 119(3):393-405.
  (*These authors contributed equally to this work.)
• Sondermann, H., Soisson, S.M., Bar-Sagi, D., and Kuriyan, J. (2003). Tandem histone folds in the structure of the N-terminal segment of the Ras activator Son of Sevenless. Structure 11(12):1583-1593.
• Harkiolaki, M., Lewitzky, M., Jones, E.Y., Bourette, R., Mouchiroud, G., Sondermann, H., Moarefi, I. and Feller, S.M. (2003). Structural basis for SH3 domain-mediated high-affinity binding between Mona/Gads and SLP-76. EMBO J 22:2571-2582.
• Margarit, S.M., Sondermann, H., Hall, B.E., Nagar, B., Hoelz, A., Pirruccello, M., Bar-Sagi, D. and Kuriyan, J. (2003). Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS. Cell 112(5):685-695.
• Sondermann, H., Ho, A.K., Listenberger, L.L., Siegers, K., Moarefi, I., Wente, S.R., Hartl, F.U. and Young, J.C. (2002). Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in S. cerevisiae. J Biol Chem 277(36):33220-33227.
• El Mourabit, H., Poinat, P., Koster, J., Sondermann, H., Wixler, V., Wegener, E., Laplantine, E., Geerts, D., Georges-Labouesse, E., Sonnenberg, A. and Aumailley, M. (2002). The PDZ domain of TIP-2/GIPC interacts with the C-terminus of the integrin α5 and α6 subunits. Matrix Biol 21(2):207-214.
• Sondermann, H., Scheufler, C., Schneider, C., Hohfeld, J., Hartl, F.U. and Moarefi, I. (2001). Structure of a Bag/Hsc70 complex: convergent functional evolution of Hsp70 nucleotide exchange factors. Science 291(5508):1553-7.
• Sondermann, H., Becker, T., Mayhew, M., Wieland, F. and Hartl, F.U. (2000). Characterization of a receptor for heat shock protein 70 on macrophages and monocytes. Biol Chem 381(12):1165-74.
• Sondermann, H., Dogic, D., Pesch, M. and Aumailley, M. (1999). Targeting of cytoskeletal linker proteins to focal adhesion complexes is reduced in fibroblasts adhering to laminin-1 when compared to fibronectin. Cell Adhes Commun 7(1):43-56.
• Obermann, W.M., Sondermann, H., Russo, A.A., Pavletich, N.P. and Hartl, F.U. (1998). In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis. J Cell Biol 143(4):901-10.