Advancing the health and well-being of animals and people

Principal Investigator: John Parker

Baker Institute for Animal Health
Contact Information:  Email:, Phone:  607-256-5626
Sponsor:  NIH-National Institute of Allergy and Infectious Diseases (NIAID) 
Grant Number: 1 R56 AI090076-01A1
Title: Regulation of Reovirus Induced Apoptosis
Annual Direct Cost:  $278,000
Project Period: 09/19/2012-08/31/2013

DESCRIPTION (provided by applicant):  The proposed studies will investigate a novel uninvestigated area of Reovirus biology that is applicable to understanding how human pathogenic viruses induce apoptosis in cells and to the development of reovirus as a therapeutic agent for cancer therapy in humans. This is relevant to public health because of the recognized importance of apoptosis in viral pathogenesis and because of the clinical promise of viral oncolytic therapy.