Dr. Andrew Miller
T5-006A Veterinary Research Tower
My laboratory is focused primarily on studying the mechanisms underlying neurologic disease in companion animals utilizing both spontaneously arising disease models and experimental models in a variety of laboratory animal species.
Dr. Andrew Miller is an Assistant Professor and the Anne Groot Sesquicentennial Fellow in the College of Veterinary Medicine. I am a diplomate of the American College of Veterinary Pathologists (ACVP). I received my doctorate in veterinary medicine from Cornell University in 2005 and completed a residency in veterinary anatomic pathology at Cornell University in 2008. I joined the faculty at the New England Primate Research Center, a division of Harvard Medical School as a research associate in 2008. I had achieved assistant professor by 2013 and held an appointment in the Pathology Department of the Massachusetts General Hospital during my tenure at the primate center. I joined the faculty in the Section of Anatomic Pathology as an Assistant Professor at Cornell University in fall of 2013. I am the Anne Groot Sesquicentennial Fellow.
My primary research interests are directed at studying spontaneously occurring neurologic diseases in our domestic animals. The current focus of my lab is in validating the dog as a model for human brain cancer, primarily meningeal and glial tumors. This is being done through a variety of histologic, immunohistochemical, and molecular studies between analogous tumors in dog and man. We are especially interested in determining the roles that novel gene mutations have in the genesis of canine meningioma. We are also actively involved in studying the immune cell microenvironment in canine brain tumors in order to determine if a relationship exists between immune cell infiltration and post-surgical outcome. Other research projects included characterizing novel causes of neurologic disease in companion animals. Lastly, I provide pathology support to understanding the pathogenesis of dorsal root ganglion pathology in simian immunodeficiency virus infected rhesus macaques through collaborations with researchers at Boston College.
I have a strong interest in training veterinary students and pathology residents and preparing them for a career in comparative veterinary pathology. I believe that this is best done through hands-on exposure to clinical cases and basic research techniques. I am involved nationally in the ACVP through the examination committee and other committees related to the national ACVP meeting. I strongly believe in the integration of teaching and collaborative research as a way to foster continued growth in the field of comparative veterinary pathology.
Selected Peer-reviewed Publications (out of 57)
- Gold J, Divers T, Miller AD, Scrivani P, Perkins G, Vanbiervliet J, deLahunta A. Cervical vertebral epidural hematomas in four horses. J Vet Int Med 2008 22(2): 481-85.
- Miller AD, Barber R, Porter BF, Peters RM, Kent M, Platt SR, Schatzberg SJ. Degenerative myelopathy in 2 Boxer dogs. Vet Pathol 2009 46(4): 684-687.
- Geiger DA, Miller AD, Cutter-Schatzberg K, Shelton GD, deLahunta A, Schatzberg SJ. Encephalomyelopathy and polyneuropathy in two Boxer littermates. Vet Pathol 2009 46(6): 1160-1165.
- Miller AD, Masek-Hammerman K, Dalecki K, Mansfield K, Westmoreland SV. Histologic and Immunohistochemical Characterization of Pheochromocytoma in Six Cotton-Top Tamarins (Saguinus oedipus). Vet Pathol 2009 46(6): 1221-1229.
- Jurney C, Haddad J, Crawford N, Miller AD, Van Winkle TJ, Vite CH, Sponenberg P, Inzana KD, Cook CR, Britt L, O’Brien DP. Polymicrogyria in standard poodles. J Vet Intern Med 2009 23(4): 871-874.
- Miller AD, Townsend AK, McGowan KG, Clark AB, Glaser AL, Patrican LA, Dobson E, Buckles EL. Non-West Nile Virus Associated Mortality in a Population of American Crows (Corvus brachyrhynchos): A Gross and Histopathologic Study. J Vet Diag Invest March 2010 22(2): 120-126.
- Bailey C, Kramer J, Mejia A, MacKey J, Mansfield KG, Miller AD. Systemic Spironucleosis in Two Immunodeficient Rhesus Macaques (Macaca mulatta). Vet Pathol 2010 47(3): 488-494.
- Miller AD, Kramer J, Lin KC, Knight H, Martinot M, Mansfield KG. Small intestinal adenocarcinoma in common marmosets (Callithrix jacchus). Vet Pathol 2010 47(5): 969-976.
- Marr-Belvin AK, Bailey C, Knight HL, Klumpp S, Westmoreland SV, Miller AD. Ovarian pathology in rhesus macaques: A 12-year retrospective. J Med Primatol 2010 39(3): 170-176.
- Krimer PM, Miller AD, Li Q, Grosenbaugh DA, Susta L, Schatzberg SJ. Molecular and pathological investigations of the central nervous system in Borrelia burgdorferi infected dogs. J Vet Diag Invest July 2011 23(4): 757-763.
- Wachtman LM, Miller AD, Xia DL, Curran E, Mansfield KG. Detection of Mycobacterium gordonae in feces is associated with positive tuberculin skin test reactions in the common marmoset (Callithrix jacchus). Comp Med 2011 61(7): 278-284.
- Assaf B, Miller AD. Pleural Endometriosis in an Aged Rhesus Macaque (Macaca mulatta): A Histopathologic and Immunohistochemical Study. Vet Pathol 2012 49(4): 636-641.
- Masek-Hammerman K, Miller AD, Lin KC, MacKey J, Weissenbock H, Gierbolini L, Burgos A, Perez H, Mansfield KG. Epizootic Myocarditis Associated with Encephalomyocarditis Virus in a Group of Rhesus Macaques (Macaca mulatta). Vet Pathol 2012 49(2): 386-392.
- Macri SC, Bailey CC, Monts de Oca N, Silva NA, Rosene DL, Mansfield KG, Miller AD. Immunophenotypic Alterations in Resident Immune Cells and Myocardial Fibrosis in the Aging Rhesus Macaque (Macaca mulatta). Toxicol Pathol 2012 40(4): 637-646. (NOTE: Cover article)
- Miller AD, Baitchman EJ, Masek-Hammerman, K. Multiple Endocardial Neurofibromas in a Rosybill Pochard (Netta peposaca). J Vet Diag Invest 2012 24(2): 408-411.
- Burdo TH, Orzechowski K, Miller AD, Williams K. Dorsal root ganglia damage in SIV-infected rhesus macaques: An animal model of HIV-induced sensory neuropathy. Am J Pathol, 2012 180(4): 1362-1369.
- Miller AD, Westmoreland SV, Evangelous NR, Graham A, Sledge J, Nesathurai S. Acute Traumatic Spinal Cord Injury Induces Glial Activation in the Cynomolgus Macaque (Macaca fascicularis). J Med Primatol, 2012 41(3): 202-209.
- Macri SC, Knight HL, Miller AD. Mesenchymoproliferative enteropathy associated with dual simian polyomavirus and rhesus cytomegalovirus infection in a simian immunodeficiency virus infected rhesus macaque (Macaca mulatta). Vet Pathol 2013, 50(4): 715-721.
- Handley SA, Thackery LB, Zhao G, Presti R, Miller AD, Droit L, Abbink P, Maxfield LF, Kambal A, Duan E, Stanley K, Kramer J, Macri S, Permar SR, Schmitz JE, Mansfield K, Brenchley JM, Veazy RS, Stappenbeck TS, Wang D, Barouch DH, Virgin HW. Pathogenic Simian Immunodeficiency Virus Infection is Associated with Expansion of the Enteric Virome. Cell 2012, 151(2): 253-266.
- Assaf BT, Knight HL, Miller AD. Rhesus cytomegalovirus (Macacine herpesvirus-3) associated facial neuritis in simian immunodeficiency infected rhesus macaques (Macaca mulatta). Vet Pathol 2015, 52(1):217-223.
- Cameron S, Rishniw M, Miller AD, Sturges B, Dewey CW. Clinical characteristics and factors affecting survival of cats undergoing surgical excision of intracranial meningiomas: A retrospective study of 121 cases (1994-2011). Vet Surg 2014, in press
- Burdo TH, Miller AD. Animal models of HIV peripheral neuropathy. Future Virol. 2014, 9(5):465-474.
- Hammond JJ, de Lahunta A, Glass EN, Kent M, Summers BA, Miller AD. Feline spinal cord gliomas: Clinicopathologic features of seven cases. J Vet Diag Invest 2014, 26(4):513-520.
- Petrosky KY, Knight HL, Westmoreland SV, Miller AD. Atypical nodular astrocytosis in simian immunodeficiency virus infected rhesus macaques (Macaca mulatta). J Med Primatol 2014, 43(6):468-476.
- De Matos R, Russell D, Van Alstine, W, Miller AD. Spontaneous fatal Human herpesvirus 1 encephalitis in two domestic rabbits (Oryctolagus cuniculus). J Vet Diagn Invest, 2014, 26(5):689-694.
- Harbison CE, Taheri F, Knight H, Miller AD. Immunohistochemical characterization of large intestinal adenocarcinoma in the rhesus macaque (Macaca mulatta). Vet Pathol, 2014, epub Nov. 3.
Chapters in Books
- Miller, AD. Neoplastic and Proliferative Disorders. In: Non-human Primates in Biomedical Research, v. 2, 2nd edition (2012), pg. 325-355.