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PREVENTION
Major advances in cancer management have occurred over the last decade. Improvements
in diagnosis, imaging and staging have identified strategies leading to better
management of cancers that are clinically detectable. In addition, significant
improvement in supportive care and in particular palliative management of cancer
is companion animals has resulted in many more options for owners considering
treatment for their pets with cancer.
However, it
is still clear that too many dogs and cats die from cancer.
Cancer control,
until recently, has been focused on treatment of already existing, clinically
detectable disease. However, this strategy is not optimal for control of most
types of cancer since even if the tumor is diagnosed when it is small (1 cm
diameter) the process is already well advanced and may be beyond our capability
of complete eradication of all cancer cells.
The goal of
cancer research is to decrease the morbidity and mortality associated with this
disease and in order to achieve this goal we must:
1) cure existing
and invasive cancer,
2) control preinvasive cancers and,
3) prevent new cancer.
Early diagnosis
and prevention could do more to reduce the impact of cancer on the lives of
companion animals than cancer treatment programs are able to accomplish. The
key to early diagnosis and prevention of cancer is to identify patients
at increased risk of cancer development at a stage when interventions will be
most successful.
CHEMOPREVENTION
New compounds specifically developed to keep tumors "differentiated"
rather than eradicate them is a rational method of cancer control since these
strategies are much less toxic than conventional therapy and may be just as
useful. This new field is called chemoprevention. Chemoprevention of cancer
is conceptually similar to prevention of cardiovascular diseases in patients
that are at high risk by administering medication to lower cholesterol and blood
pressure before any symptoms occur. An example of chemoprevention for cancer
in women is the use of tamoxifen to reduce the incidence of recurrent breast
cancer.
From this
information, specific screening programs and owner recommendations for prevention
and surveillance of these cancers can be developed as described below.
WHAT CAN I
DO TO HELP MY PET?
Prevention is the best defense against cancer. Besides giving your animal the
healthy basics of life such as good food, clean water, regular exercise and
grooming, there are other things that you can do to keep your animal well.
Early
spay and neuter
Regular examinations- 2X year for animals over 8 years old
Frequent oral exams
Attention to changes in eating and bowel habits
General
Recommendations for Cancer Screening
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