STRYCHNINE TOXICITY
 
Description    Malicious poisoning with strychnine is possible but most toxicity is due to rodenticides or overdoses of medicinals containing strychnine. Poisoned animals become very excitable and might seizure at the slightest stimulus; death can occur during a seizure.
 
Species   Bovine, Canine, Equine, Feline, Caprine, Ovine, Porcine
 
Signs   Ataxia, Back spasms, Cyanosis, Dysmetria, Dyspnea, Excessive salivation, Excitement, Exophthalmos, Fever, Forelimb lameness, Forelimb spasms, Generalized lameness or stiffness, Head, face, neck spasms, Hindlimb lameness, Hindlimb spasms, Hyperesthesia, Hypertonia of muscles, myotonia, Inability to stand, Increased respiratory rate, Mydriasis, Opisthotonus, Prolapsed third eyelid, Seizures or syncope, Stiffness or extended neck, Sudden death, Sweating, Tetany, Trembling, Tremor, Vomiting or regurgitation
 
References   Niles GA. Toxicoses of the Ruminant Nervous System. Vet Clin North Am Food Anim Pract 2017;33:111 [Web Reference]
Cowan V. Characterizing 1341 cases of veterinary toxicoses confirmed in western Canada: A 16-year retrospective study. Can Vet J 2016;57:53 [Web Reference]
Cowan VE. A retrospective study of canine strychnine poisonings from 1998 to 2013 in western Canada. Can Vet J 2015;56:587 [Web Reference]
Dawson DR. Toxins and Adverse Drug Reactions Affecting the Equine Nervous System. Vet Clin N A Eq Pract 2011;27:507 [Web Reference]
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