TREMORGENIC PENICILLIUM OR ASPERGILLUS MYCOTOXICOSIS, TOXINS, TOXICITY
 
Description    Several isolates of PENICILLIUM and ASPERGILLUS produce toxins that produce clinical signs but field cases are rare. Toxicosis can be associated with garbage ingestion in dogs. Recovery, which might take a week in dogs, is generally complete. Cattle and sheep consuming barley products, sprouted wheat, corn sprouts, beetroot screenings or beer residues contaminated with the fungus ASPERGILLUS CLAVATUS have developed a neurologic syndrome.
 
Species   Bovine, Canine, Ovine
 
Signs   Abnormal behavior, aggression, changing habits, Abnormal forelimb reflexes, Abnormal hindlimb reflexes, Abnormal lung or pleural sounds, Abnormal proprioceptive positioning, Agalactia, Anorexia, Ataxia, Blepharospasm, Coma, Congestion oral mucous membranes, Constant or increased vocalization, Dehydration, Diarrhea, Dullness, Dysmetria, Dyspnea, Excessive salivation, Excitement, Exercise intolerance, Fever, Flatulence, Generalized lameness or stiffness, Generalized weakness, Hyperesthesia, Inability to stand, Increased respiratory rate, Mydriasis, Nystagmus, Opisthotonus, Paraparesis, Reluctant to move, Seizures or syncope, Tachycardia, Tetany, Tetraparesis, Trembling, Tremor, Vomiting or regurgitation
 
References   Kormpou F. Use of Intravenous Lipid Emulsion in Dogs With Suspected Tremorgenic Mycotoxicosis: 53 Cases. Vet Evidence 2018;May [Web Reference]
Ogunade IM. Silage review: Mycotoxins in silage: Occurrence, effects, prevention, and mitigation. J Dairy Sci 2018;101:4034 [Web Reference]
Gibbons P. Cerebellar Disease of Ruminants. Vet Clin North Am Food Anim Pract 2017;33:59 [Web Reference]
Riet-Correa F. Mycotoxicoses of ruminants and horses. J Vet Diagn Invest 2013;25:692 [Web Reference]
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