VITAMIN D3 TOXICITY, HEART AND GREAT VESSEL CALCIFICATION, IN CATTLE
 
Description    Large parenteral doses of vitamin D3 caused prolonged hypercalcemia and death in cows. Calcification of the heart and great vessels can occur.
 
Species   Bovine
 
Signs   Agalactia, Anorexia, Arrhythmia, Bradycardia, Decreased amount of stools, absent feces, constipation, Dryness of skin or hair, Dullness, Dyspnea, Fever, Generalized lameness or stiffness, Generalized weakness, Heart murmur, Inability to stand, Increased respiratory rate, Jugular pulse, Peripheral venous distention, Polydipsia, Polyuria, Rough hair coat, Subcutaneous crepitation, Tachycardia, Torticollis, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Ventricular premature beat, Weight loss
 
References   Osweiler GD. Toxicology. Vet Clin N A Food Anim Pract 2000;16:409
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