LUPINE POISONING, CROOKED CALF DISEASE
 
Description    Malformations occur in calves of pregnant cattle that graze certain species of lupine (LUPINUS) in early gestation. Adults might show signs of toxicity or very few effects. Seen mainly in the western U.S. The malformations can lead to dystocia.
 
Species   Bovine
 
Signs   Abnormal forelimb curvature, Abnormal hindlimb curvature, Ataxia, Cleft palate or lip, Contracture fore limb, leg, Contracture hind limb, leg, Decreased mobility of forelimb joint, Decreased mobility of hindlimb joint, Decreased, absent mobility joint, head face neck, Decreased, absent mobility, back, Dysmetria, Excessive salivation, Forelimb lameness, Generalized lameness or stiffness, Generalized weakness, Hindlimb lameness, Inability to stand, Kyphosis, Prolapsed third eyelid, Scoliosis, Sudden death, Torticollis, Trembling, Tremor
 
References   Dittmer KE. Approach to Investigating Congenital Skeletal Abnormalities in Livestock. Vet Pathol 2015;52:851 [Web Reference]
Panter KE. Effects of Xenobiotics and Phytotoxins on Reproduction in Food Animals. Vet Clin N A Food Anim Pract 2011;27:429 [Web Reference]
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