NITRATE, NITRITE, POISONING IN RUMINANTS
 
Description    Although nitrate is relatively nontoxic ruminants convert it into the more toxic nitrite, leading to a sometimes fatal methemaglobinemia. High-nitrate water, hay, corn fodder grown during drought, rape, kale, turnips, beets, and mangels are common sources. Brown blood is a characteristic sign. Lambs grazing on pastures recently topdressed with nitrogenous fertilizers can develop signs of sometimes-fatal gastrointestinal disease.
 
Species   Bovine, Caprine, Ovine
 
Signs   Abnormal behavior, aggression, changing habits, Abortion or weak newborns, Agalactia, Anorexia, Ataxia, Brown color, mucous membranes, Cold skin, Colic, Coma, Cyanosis, Diarrhea, Dullness, Dysmetria, Dyspnea, Excessive salivation, Excitement, Exercise intolerance, Female infertility, Generalized weakness, Hyperesthesia, Hypothermia, Inability to stand, Increased frequency of urination, Increased respiratory rate, Lack of growth or weight gain, Opisthotonus, Pain on external abdominal pressure, Paraparesis, Polydipsia, Polyuria, Seizures or syncope, Sudden death, Tachycardia, Tetraparesis, Trembling, Tremor, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Urinary incontinence, Vomiting or regurgitation, Weak pulse, Weight loss
 
References   Patton TG. Detecting Methemoglobinemia in Animals with a Drop of Blood. PLoS ONE 2016;11:e0167942 [Web Reference]
Cowan V. Characterizing 1341 cases of veterinary toxicoses confirmed in western Canada: A 16-year retrospective study. Can Vet J 2016;57:53 [Web Reference]
Payne J. Plant poisoning in farm animals. In Pract 2014;36:455 [Web Reference]
Lovatt F. Sudden death in sheep. In Pract 2014;36:409 [Web Reference]
Ensley S. Ruminant Toxicology Diagnostics. Vet Clin N A Food Anim Pract 2012;28:557 [Web Reference]
Finnie J. Neurological diseases of ruminant livestock in Australia. II: toxic disorders and nutritional deficiencies. Aust Vet J 2011;89:247 [Web Reference]
Bischoff K. Toxic Plants of the Northeastern United States. Vet Clin N A Food Anim Pract 2011;27:459 [Web Reference]
Nicholson SS. Southeastern Plants Toxic to Ruminants. Vet Clin N A Food Anim Pract 2011;27:447 [Web Reference]
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