Description    Plants of the COTYLEDON, TYLECODON, and KALANCHOE species (CRASSULACEAE) in Africa can cause cardiac and neurologic disease. This condition has been experimentally reproduced.
Species   Caprine, Ovine
Signs   Agalactia, Anorexia, Ataxia, Back spasms, Bloat in ruminants, Bradycardia, Decreased respiratory rate, Dehydration, Diarrhea, Dullness, Dyspnea, Excessive salivation, Exercise intolerance, Fever, First degree atrioventricular heart block, Forelimb spasms, Generalized weakness, Head, face, neck spasms, Hindlimb spasms, Inability to stand, Increased respiratory rate, Miosis, Mucoid nasal discharge, Neck weakness, Pale, Paraparesis, Reluctant to move, Rumen hypomotility or atony, Second degree atrioventricular heart block, Sinus arrhythmia, Sudden death, Tachycardia, Tetraparesis, Third degree, complete, atrioventricular heart block, Torticollis, Trembling, Tremor
References   Botha CJ. Toxicokinetics of cotyledoside following intravenous administration to sheep. J S Afr Vet Assn 2003;74:7 [Web Reference]
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