Description    Clinical signs of lead toxicity are usually seen in younger animals and might include gastrointestinal problems, megaesophagus, nervous system dysfunction and anemia. Neutrophilic leucocytosis, moderate anemia and basophilic stippling of RBC are frequently observed. There might be lead lines in the metaphyses of the long bones.
Species   Canine, Feline
Signs   Abnormal behavior, aggression, changing habits, Abnormal proprioceptive positioning, Anorexia, Ataxia, Blindness, Bloody stools, feces, hematochezia, Circling, Colic, Coma, Constant or increased vocalization, Deafness, Decreased amount of stools, absent feces, constipation, Dehydration, Diarrhea, Dullness, Dysmetria, Dysphagia, Enophthalmos, Excessive salivation, Excitement, Fever, Generalized weakness, Glucosuria, Head pressing, Head tilt, Hyperesthesia, Miosis, Mydriasis, Nystagmus, Opisthotonus, Pain on external abdominal pressure, Pale, Photophobia, Pica, Polydipsia, Polyuria, Prolapsed third eyelid, Propulsion, Proteinuria, Seizures or syncope, Tachycardia, Trembling, Tremor, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss
References   Langlois DK. Investigation of blood lead concentrations in dogs living in Flint, Michigan. JAVMA 2017;251:912 [Web Reference]
King J. Proximal tubular nephropathy in two dogs diagnosed with lead toxicity. Aust Vet J 2016;94:280 [Web Reference]
Høgåsen HR. Lead intoxication in dogs: risk assessment of feeding dogs trimmings of lead-shot game. BMC Vet Res 2016;12:152 [Web Reference]
Knight TE. Lead toxicosis in cats- a review. J Fel Med Surg 2003;5:249 [Web Reference]
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