Description    Systemic Lupus Erythematosus is an autoimmune disease that affects multiple systems. Diagnostic criteria differ among clinicians but frequent clinical signs include polyarthritis, fever, renal disorders, anemia, and skin disease. Discoid Lupus Erythematosus is confined to the skin.
Species   Canine, Feline
Signs   Abnormal behavior, aggression, changing habits, Abnormal forelimb reflexes, Abnormal hindlimb reflexes, Alopecia, Anorexia, Ataxia, Decreased mobility of forelimb joint, Decreased mobility of hindlimb joint, Dehydration, Diarrhea, Dryness of skin or hair, Dullness, Dysmetria, Dysphagia, Dysuria, Fever, Forelimb atrophy, Forelimb lameness, Forelimb pain, Forelimb swelling, Generalized lameness or stiffness, Generalized weakness, Head, face, jaw, tongue atrophy, Hematuria, Hemoglobinuria or myoglobinuria, Hemorrhage of any body part or clotting failure, Hindlimb atrophy, Hindlimb lameness, Hindlimb pain, Hindlimb swelling, Hyperesthesia, Hyperkeratosis, Increased respiratory rate, Lymphadenopathy, Male infertility, Muscle hypotonia, Nasal mucosal ulcers, vesicles, Oral mucosal ulcers, vesicles, Pale, Papule, pustule, vesicle, ulcer penis or prepuce, Paraparesis, Pelvic atrophy, Petechiae, ecchymoses, purpura, Polydipsia, Polyuria, Proteinuria, Pruritus, Red or brown urine, Reluctant to move, Retinal detachment, Retinal hemorrhage, Rough hair coat, Scarred skin, Seizures or syncope, Skin crusts, Skin erythema, Skin hyperpigmentation, Skin hypopigmentation, Skin necrosis, Skin pain, Skin papules, Skin plaque, Skin scales, Skin ulcer, Skin vesicles, Swelling skin or subcutaneous, Tachycardia, Tenesmus, Tetraparesis, Thin skin, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Vulval ulcers, vesicles, Weight loss
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