Description    Ehrlichiosis in dogs is caused by the tick-borne bacteria EHRLICHIA CANIS, E. CHAFFEENSIS, and/or E. EWINGII. The obligate-intracellular Gram-negative bacterium EHRLICHIA CANIS, the cause of Monocytic Ehrlichiosis, has a tropism for monocytes and macrophages. It is transmitted by the brown dog tick RHIPICEPHALUS SANGUINEUS. E. CANIS can cause a hemorrhagic disease with platelet dysfunction but most cases present with nonspecific signs such as depression and weight loss. Recovery is accompanied by latent infection. There is often thrombocytopenia, anemia (mainly normocytic normochromic) and lymphopenia. This is an important disease in the southern U.S. Monoclonal gammopathy can occur and ehrlichiosis should be considered in cases with such a gammopathy and no other disease. E. CHAFFEENSIS and E. EWINGII produce mild disease.
Species   Canine
Signs   Abnormal breath odor, Abnormal lung or pleural sounds, Abnormal proprioceptive positioning, Abnormal pupillary response to light, Abnormal retinal pigmentation, Abnormal retinal reflectivity, Abnormal size of retinal vessels, Abortion or weak newborns, Alopecia, Anorexia, Arrhythmia, Ascites, Ataxia, Back pain, Blepharospasm, Blindness, Bloody stools, feces, hematochezia, Cataract, Chemosis, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Corneal edema, opacity, Corneal ulcer, Coughing, Cyanosis, Decreased tearing, lacrimation, Dehydration, Diarrhea, Dullness, Dysmetria, Dyspnea, Epistaxis, Exercise intolerance, Female infertility, Fever, Forefoot swelling, Forelimb lameness, Forelimb pain, Forelimb swelling, Generalized lameness or stiffness, Generalized weakness, Head tilt, Heart murmur, Hematemesis, Hematuria, Hemoglobinuria or myoglobinuria, Hemorrhage of any body part or clotting failure, Hepatosplenomegaly, Hindfoot swelling, Hindlimb lameness, Hindlimb pain, Hindlimb swelling, Hyperesthesia, Hyphema, Hypopyon, lipid, or fibrin, flare, of anterior chamber, Hypothermia, Icterus, Inability to stand, Increased respiratory rate, Internal abdominal mass, Lack of libido or erection, Lacrimation, Lens luxation, Lymphadenopathy, Melena or occult blood in feces, stools, Miosis, Mucoid nasal discharge, Mydriasis, Nystagmus, Oral mucosal ulcers, vesicles, Pain on external abdominal pressure, Pain, neck, cervical, throat, Pale, Papilledema, Paraparesis, Petechiae, ecchymoses, purpura, Polydipsia, Polyuria, Proteinuria, Pulse deficiency, Purulent discharge from eye, Purulent nasal discharge, Red or brown urine, Reluctant to move, Retinal detachment, Retinal hemorrhage, Seizures or syncope, Skin edema, Sneezing, Swelling skin or subcutaneous, Tachycardia, Tetraparesis, Trembling, Tremor, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss
References   Aroch I. Neospora caninum and Ehrlichia canis co-infection in a dog with meningoencephalitis. Vet Clin Pathol. 2018;Feb [Web Reference]
Malik MI. Molecular detection of Ehrlichia canis in dogs from three districts in Punjab (Pakistan). Vet Med Sci 2018;Feb [Web Reference]
Jenkins S. Efficacy of Minocycline in Naturally Occurring Nonacute Ehrlichia canis Infection in Dogs. J Vet Intern Med 2018;32:217 [Web Reference]
Palacios M. High-Dose Filgrastim Treatment of Nonregenerative Pancytopenia Associated With Chronic Canine Ehrlichiosis. Topics Companion Anim Med 2017;32:28 [Web Reference]
Kaewmongkol G. Association of Ehrlichia canis, Hemotropic Mycoplasma spp. and Anaplasma platys and severe anemia in dogs in Thailand. Vet Microbiol 2017;201:195 [Web Reference]
Copyright © 2018 Cornell University College of Veterinary Medicine