Description    Thallium, a heavy metal, was a commonly-used rodenticide; production ceased but sporadic cases are still seen from various sources. Absorbed by skin or GI tract and metabolized very slowly. Animals surviving the acute phase might relapse to chronic toxicity in 5-7 days, with massive hair loss and erythematous oozing skin lesions in areas of friction.
Species   Canine, Feline
Signs   Abnormal behavior, aggression, changing habits, Abnormal size testes/scrotum, Alopecia, Anorexia, Ataxia, Bloody stools, feces, hematochezia, Change in voice, Chemosis, Colic, Coma, Congestion oral mucous membranes, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Constant or increased vocalization, Cracked skin, Dark color stools, feces, Decreased, absent thirst, hypodipsia, adipsia, Dehydration, Diarrhea, Dryness oral mucosa, Dullness, Dysmetria, Dyspnea, Excessive salivation, Fever, Generalized weakness, Head tilt, Hematemesis, Hindlimb lameness, Hyperesthesia, Hyperkeratosis, Increased respiratory rate, Kyphosis, Lacrimation, Matted or dirty hair, Melena or occult blood in feces, stools, Moist skin, hair or feathers, Oral mucosal ulcers, vesicles, Pain on external abdominal pressure, Paraphimosis or priapism, Pharyngeal ulcers, vesicles, Proteinuria, Purulent discharge from eye, Purulent discharge skin, Seizures or syncope, Skin crusts, Skin edema, Skin erythema, Skin necrosis, Skin pain, Skin papules, Skin pustules, Skin scales, Skin ulcer, Tachycardia, Tenesmus, Tongue ulcers, vesicles, Trembling, Tremor, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weak pulse, Weight loss
References   Puschner B. Thallium toxicosis in a dog consequent to ingestion of Mycoplasma agar plates. J Vet Diagn Invest 2012;24:227 [Web Reference]
Dickinson PJ. Feline neuromuscular disorders. Vet Clin N A: Small Anim Pract 2004;34:1307 [Web Reference]
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