SELENIUM TOXICITY IN HORSES, CHRONIC, ACUTE
 
Description    Failure to thrive associated with laminitis, sloughing of the hooves, and loss of hair in the mane and tail has been associated with high selenium levels in the diet. Vesicles and exudation of the mucosa of the lips, nostrils, prepuce, and anus have been reported. Chronic Selenium Toxicity is generally limited to areas with high soil selenium but could be caused by excessive supplementation of the diet. Acute Selenium Toxicity followed intravenous injection of a large amount of selenium; there was a sudden onset of signs of distress and death.
 
Species   Equine
 
Signs   Alopecia, Anorexia, Ataxia, Cool nail, claw, hoof, Diarrhea, Dullness, Dysmetria, Dyspnea, Female infertility, Fever, Forefoot pain, Forefoot swelling, Forelimb lameness, Forelimb pain, Generalized lameness or stiffness, Hindfoot pain, Hindfoot swelling, Hindlimb lameness, Hindlimb pain, Hyperesthesia, Inability to stand, Increased respiratory rate, Nail, claw, hoof sloughing, Oral mucosal ulcers, vesicles, Reluctant to move, Rough hair coat, Skin hypopigmentation, Skin vesicles, Splitting nail, claw, hoof, Sudden death, Sweating, Tachycardia, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Weight loss
 
References   Rosychuk RAW. Noninflammatory, Nonpruritic Alopecia of Horses. Vet Clin N A Eq Pract 2013;29:629 [Web Reference]
Dawson DR. Toxins and Adverse Drug Reactions Affecting the Equine Nervous System. Vet Clin N A Eq Pract 2011;27:507 [Web Reference]
Desta B. Acute selenium toxicosis in polo ponies. J Vet Diagn Invest 2011;23:623 [Web Reference]
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