Description    Nonsteroidal anti-inflammatory, antipyretic drugs can be toxic. Gastrointestinal, renal, and/or hepatotoxicity are most common.
Species   Canine, Feline
Signs   Abnormal behavior, aggression, changing habits, Anorexia, Ascites, Ataxia, Bloody stools, feces, hematochezia, Brown color, mucous membranes, Chemosis, Cold skin, Colic, Coma, Cyanosis, Dark color stools, feces, Decreased amount of stools, absent feces, constipation, Decreased, absent thirst, hypodipsia, adipsia, Dehydration, Diarrhea, Dullness, Dysmetria, Dyspnea, Excessive salivation, Excitement, Generalized weakness, Head, face, ears, jaw, nose, nasal, swelling, Hematemesis, Hematuria, Hemoglobinuria or myoglobinuria, Hyperesthesia, Hypothermia, Icterus, Inability to stand, Increased respiratory rate, Melena or occult blood in feces, stools, Neck swelling, Oliguria or anuria, Oral mucosal ulcers, vesicles, Pain on external abdominal pressure, Pale, Paraparesis, Polydipsia, Polyuria, Prolonged capillary refill time, Proteinuria, Red or brown urine, Seizures or syncope, Skin edema, Tachycardia, Tetraparesis, Trembling, Tremor, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss
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Hunt JR. An analysis of the relative frequencies of reported adverse events associated with NSAID administration in dogs and cats in the United Kingdom. Vet J 2015;206:183 [Web Reference]
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Koenigshof AM. Effect of sorbitol, single, and multidose activated charcoal administration on carprofen absorption following experimental overdose in dogs. J Vet Emerg Crit Care 2015;25:606 [Web Reference]
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Bates N. Common questions in veterinary toxicology. JSAP 2015;56:298 [Web Reference]
Cortinovis C. Poisoning of dogs and cats by drugs intended for human use. Vet J 2015;203:52 [Web Reference]
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