| FAMILIAL, HEREDITARY RENAL DISEASE, NEPHRITIS, DYSPLASIA, JUVENILE NEPHROPATHY | |
| Description | Congenital renal disorders including renal dysplasia, glomerulopathy, and tubular dysfunctions, should be suspected in young dogs with advanced renal failure in the absence of other causes. Rarely reported in cats. |
| Species | Canine, Feline |
| Signs | Abdominal distention, Abnormal breath odor, Anorexia, Ascites, Back pain, Cold skin, Coma, Dehydration, Diarrhea, Dullness, Epistaxis, Glucosuria, Hematemesis, Hematuria, Hypothermia, Increased frequency of urination, Lack of growth or weight gain, Oral mucosal ulcers, vesicles, Pain on external abdominal pressure, Pain, kidney, ureters, on palpation, Pale, Palpable small kidney, Polydipsia, Polyuria, Proteinuria, Retinal detachment, Retinal hemorrhage, Skin edema, Tachycardia, Tongue ulcers, vesicles, Trembling, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss |
| References | Aresu L et al. Bilateral juvenile renal dysplasia in a Norwegian Forest Cat. Journal of Feline Medicine & Surgery 2009;11:326-329 [Web Reference] KolbjØrnsen Ø et al. End-Stage Kidney Disease Probably due to Reflux Nephropathy with Segmental Hypoplasia (Ask-Upmark Kidney) in Young Boxer Dogs in Norway. A Retrospective Study. Vet Pathol 2008;45:467-474 [Web Reference] Chandler ML et al. Juvenile nephropathy in 37 boxer dogs. Journal of Small Animal Practice 2007;48:690–694 [Web Reference] Davidson AG et al. Genetic Cause of Autosomal Recessive Hereditary Nephropathy in the English Cocker Spaniel. J Vet Intern Med 2007;21:394–401 [Web Reference] Raila J et al. Renal Pathology and Urinary Protein Excretion in a 14-Month-Old Bernese Mountain Dog with Chronic Renal Failure. Journal of Veterinary Medicine Series A 2007;54:131–135 [Web Reference] Wakamatsu N et al. Histologic and Ultrastructural Studies of Juvenile Onset Renal Disease in Four Rottweiler Dogs. Vet Pathol 2007;44:96-100 [Web Reference] |