GRANULOMATOUS AND HEMORRHAGIC SYNDROME IN CATTLE, SYSTEMIC, MULTISYSTEMIC
 
Description    Granulomatous and Hemorrhagic Syndrome in cattle is Idiopathic or has been associated with: Vetch (VICIA); Citrus Pulp; Di-ureido iso-butane; Brassica; A silage additive containing formalin in sulphuric acid with the addition of methanol and urea; or Bovine Herpesvirus 4.
 
Species   Bovine
 
Signs   Abnormal behavior, aggression, changing habits, Abortion or weak newborns, Agalactia, Alopecia, Anorexia, Bloody stools, feces, hematochezia, Chemosis, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Coughing, Cracked skin, Dehydration, Diarrhea, Dullness, Dyspnea, Epistaxis, Excessive salivation, Excitement, Fever, Generalized lameness or stiffness, Generalized weakness, Hematuria, Hemoglobinuria or myoglobinuria, Hemorrhage of any body part or clotting failure, Hyperesthesia, Hyperkeratosis, Hypothermia, Icterus, Inability to stand, Increased respiratory rate, Lack of growth or weight gain, Lacrimation, Lymphadenopathy, Melena or occult blood in feces, stools, Moist skin, hair or feathers, Mucoid nasal discharge, Pale, Petechiae, ecchymoses, purpura, Pica, Polydipsia, Pruritus, Purulent discharge from eye, Purulent nasal discharge, Red or brown urine, Reluctant to move, Rough hair coat, Skin crusts, Skin edema, Skin erythema, Skin papules, Skin plaque, Skin pustules, Skin scales, Skin ulcer, Sudden death, Swelling skin or subcutaneous, Tachycardia, Tetraparesis, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Unusual or foul odor, stools, feces, Weight loss
 
References   Rawdon TG. Systemic granulomatous and haemorrhagic syndrome in New Zealand dairy cattle. N Z Vet J 2017;65:156 [Web Reference]
Bellino C. Potential Pathogenetic Role of Bovine Herpesvirus 4 in Two Dairy Cows with Dermatitis-Pyrexia-Hemorrhagic Syndrome. J Clin Microbiol 2015;53:2763 [Web Reference]
Washburn K. Hairy vetch (VICA VILLOSA) toxicosis in a purebred angus herd. Bovine Practitioner 2007;41:60
Iizuka A. An outbreak of systemic granulomatous disease in cows with high milk yields. J Vet Med Sci 2005;67:693 [Web Reference]
Saunders GK. Suspected citrus pulp toxicosis in dairy cattle. J Vet Diagn Invest 2000;12:269 [Web Reference]
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