HEPATIC NECROSIS, TOXIC , BACTERIAL, HEPATOPATHY, ACUTE HEPATITIS, IN CATS AND DOGS
 
Description    In Toxic Hepatopathy there is hepatocytic necrosis with little inflammation on liver biopsy. Can be due to a known toxin but in some cases no such agent can be identified. Several bacteria have been associated with Hepatitis. Severity ranges from acutely-fatal to chronic subclinical disease.
 
Species   Canine, Feline
 
Signs   Abdominal distention, Abnormal proprioceptive positioning, Anorexia, Ataxia, Blindness, Bloody stools, feces, hematochezia, Bradycardia, Cold skin, Coma, Decreased amount of stools, absent feces, constipation, Dehydration, Diarrhea, Dullness, Dysmetria, Excessive salivation, Fever, Generalized weakness, Hematemesis, Hematuria, Hemorrhage of any body part or clotting failure, Hepatosplenomegaly, Hypothermia, Icterus, Increased respiratory rate, Melena or occult blood in feces, stools, Mucous, mucoid stools, feces, Pain on external abdominal pressure, Pale, Polydipsia, Polyuria, Prolonged capillary refill time, Red or brown urine, Reluctant to move, Sudden death, Tachycardia, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss
 
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Lester C. Retrospective evaluation of acute liver failure in dogs (19952012): 49 cases. J Vet Emerg Crit Care 2016;26:559 [Web Reference]
Irvine KL. Sarcocystid organisms found in bile from a dog with acute hepatitis: a case report and review of intestinal and hepatobiliary Sarcocystidae infections in dogs and cats. Vet Clin Pathol 2016;45:57 [Web Reference]
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