REACTIVE HISTIOCYTOSIS IN DOGS
 
Description    Dogs can develop cutaneous histiocytic lesions of unknown cause. There are multiple 1-5-cm diameter erythematous plaques or nodules in the skin and sometimes the nasal planum (`clown nose`). Histologically these consisted of dermal or pannicular infiltrates of large histiocytic cells and varying numbers of other inflammatory cells. Lesions seemed to wax and wane. Ocular involvement is rare.
 
Species   Canine
 
Signs   Abnormal pupillary response to light, Abnormal upper airway breathing sounds, Alopecia, Anorexia, Back swelling, Blindness, Chemosis, Dullness, Exophthalmos, Forefoot swelling, Head, face, ears, jaw, nose, nasal, swelling, Hindfoot swelling, Lymphadenopathy, Moist skin, hair or feathers, Mydriasis, Neck swelling, Orbital, periorbital, periocular, conjunctival swelling, Skin erythema, Skin fistula, Skin plaque, Skin ulcer, Swelling skin or subcutaneous, Swelling, mass external abdomen, Thoracic swelling, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Weight loss
 
References   Hardy J. Skin diseases affecting the nasal planum and footpads of dogs. In Pract 2017;39:203 [Web Reference]
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