BARBITURATE TOXICITY IN DOGS AND CATS
 
Description    Dogs and cats that eat the carcasses of animals euthanized with barbiturates or that get the drug from another source are at risk of developing toxicosis. Uptake is rapid with signs developing in about 1/2 hour after ingestion.
 
Species   Canine, Feline
 
Signs   Abnormal anal, perineal, tail reflexes, Abnormal forelimb reflexes, Abnormal hindlimb reflexes, Abnormal panniculus reflex, Abnormal proprioceptive positioning, Abnormal pupillary response to light, Arrhythmia, Ataxia, Bradycardia, Coma, Congestion oral mucous membranes, Cyanosis, Decreased or absent menace response but not blind, Decreased respiratory rate, Disoriented, Dullness, Dysmetria, Dysphagia, Dyspnea, Excessive or decreased sleeping, Generalized weakness, Head, face, ears, jaw weakness, droop, Hypothermia, Inability to stand, Increased respiratory rate, Miosis, Mydriasis, Paraparesis, Sinus arrhythmia, Sinus tachycardia, Sudden death, Tetraparesis, Trembling, Tremor, Weak pulse
 
References   Lee JA. Emergency Management and Treatment of the Poisoned Small Animal Patient. Vet Clin N A Sm Anim Pract 2013;43:757 [Web Reference]
Kaiser AM. Secondary pentobarbital poisoning in two dogs: a cautionary tale. J Vet Diagn Invest 2010;22:632 [Web Reference]
Brauer C. Barbiturate intoxication in two dogs confirmed by toxicological urinalysis. JSAP 2009;50:423 [Web Reference]
Campbell VL. Use of a point-of-care urine drug test in a dog to assist in diagnosing barbiturate toxicosis secondary to ingestion of a euthanized carcass. J Vet Emerg Crit Care 2009;19:286 [Web Reference]
Teitler JB. Evaluation of a Human On-site Urine Multidrug Test for Emergency Use With Dogs. JAAHA 2009;45:59 [Web Reference]
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