FOCAL SYMMETRICAL POLIOMYELOMALACIA, SELENIUM TOXICITY IN PIGS
 
Description    Progressive afebrile paresis characterized by gross and microscopic evidence of Focal Symmetrical Poliomyelomalacia has been seen in pigs. Outbreaks have been reported from some farms. Pigs that do not die might remain bright and alert. Has been associated with high selenium levels in feed and tissues of affected animals and was reproduced by feeding rations with as little as 20 ppm Se in the diet and by experimental administration of selenium.
 
Species   Porcine
 
Signs   Abnormal forelimb reflexes, Abnormal hindlimb reflexes, Abnormal proprioceptive positioning, Alopecia, Anorexia, Ataxia, Coma, Cyanosis, Diarrhea, Dullness, Dysmetria, Dyspnea, Fever, Forefoot swelling, Forelimb lameness, Generalized lameness or stiffness, Generalized weakness, Hindfoot swelling, Hindlimb hypoesthesia, Hindlimb lameness, Inability to stand, Increased respiratory rate, Lacrimation, Nail, claw, hoof sloughing, Paraparesis, Rough hair coat, Skin erythema, Sudden death, Tachycardia, Tetraparesis, Trembling, Vomiting or regurgitation, Weak pulse, Weakness of one hindlimb
 
References   Nathues H. Peracute selenium toxicosis followed by sudden death in growing and finishing pigs. Can Vet J 2010;51:515 [Web Reference]
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