BROMETHALIN TOXICITY
 
Description    The neurotoxic rodenticide Bromethalin is the active ingredient in many commercial rat and mouse baits. Convulsive or progressive-paralytic syndromes are the typical presentations.
 
Species   Canine, Feline
 
Signs   Abdominal distention, Abnormal behavior, aggression, changing habits, Abnormal forelimb reflexes, Abnormal hindlimb reflexes, Abnormal proprioceptive positioning, Abnormal pupillary response to light, Anisocoria, Anorexia, Arrhythmia, Ataxia, Blindness, Change in voice, Circling, Colic, Coma, Constant or increased vocalization, Cyanosis, Disoriented, Dullness, Dysmetria, Dyspnea, Dysuria, Enlarged, distended, urinary bladder, Excessive salivation, Excitement, Fever, Forelimb hypoesthesia, Forelimb spasms, Generalized weakness, Head pressing, Hindlimb hypoesthesia, Hyperesthesia, Inability to stand, Increased respiratory rate, Miosis, Nystagmus, Opisthotonus, Pain on external abdominal pressure, Pain, neck, cervical, throat, Paraparesis, Propulsion, Seizures or syncope, Sinus arrhythmia, Sudden death, Tachycardia, Tetraparesis, Trembling, Tremor, Urinary incontinence, Vomiting or regurgitation
 
References   Romano MC. Fatal bromethalin intoxication in 3 cats and 2 dogs with minimal or no histologic central nervous system spongiform change. J Vet Diagn Invest 2018;May [Web Reference]
Copyright © 2018 Cornell University College of Veterinary Medicine