IONOPHORE, MONENSIN, LASALOCID, SALINOMYCIN TOXICITY IN HORSES
 
Description    Monensin, lasalocid, and salinomycin are antibiotics used as feed additives for food animals; horses can accidentally be exposed to these drugs. Exercise intolerance and cardiac problems can follow for several months after monensin exposure.
 
Species   Equine
 
Signs   Abnormal lung or pleural sounds, Abnormal proprioceptive positioning, Agalactia, Anorexia, Arrhythmia, Ataxia, Atrial fibrillation, Atrial tachycardia, Back atrophy, Colic, Coma, Congestion oral mucous membranes, Cyanosis, Decreased borborygmi, Dehydration, Diarrhea, Dullness, Dysmetria, Dysphagia, Dyspnea, Enlarged, distended, urinary bladder, Excessive salivation, Exercise intolerance, Fever, Forelimb atrophy, Generalized weakness, Head, face, ears, jaw, nose, nasal, swelling, Hemoglobinuria or myoglobinuria, Hindlimb atrophy, Inability to stand, Increased respiratory rate, Jugular pulse, Neck, chest atrophy, Pale, Paraparesis, Pelvic atrophy, Red or brown urine, Reluctant to move, Rough hair coat, Second degree atrioventricular heart block, Seizures or syncope, Skin edema, Skin plaque, Sudden death, Sweating, Tachycardia, Tetraparesis, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Ventricular fibrillation, flutter, Ventricular premature beat, Ventricular tachycardia, Weak pulse, Weight loss
 
References   Al-Dissi A. Toxicology for the Equine Practitioner. Vet Clin N A Eq Pract 2015;31:269 [Web Reference]
Bautista AC. Diagnostic value of tissue monensin concentrations in horses following toxicosis. J Vet Diagn Invest 2014;26:423 [Web Reference]
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