Description    Luxations of the lens can be congenital; secondary to trauma, glaucoma, uveitis, or cataracts; or primary in the absence of ocular disease. Bilateral or initially-unilateral displacement of the lens, usually into the anterior chamber, is inherited as an autosomal recessive in some dog breeds; can be congenital but signs are generally seen from 3- to 8-years of age. Bilateral apparently-inherited lens instability was reported in domestic shorthair cats.
Species   Canine, Equine, Feline
Signs   Abnormal pupillary response to light, Abnormal pupillary shape or defect in the iris, Anisocoria, Blepharospasm, Blindness, Buphthalmia, Cataract, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Corneal edema, opacity, Lacrimation, Lens luxation, Mydriasis, Ocular pain, Opacity or precipitates in vitreous, Photophobia, Retinal detachment, Synechia
References   Oliver JAC. Evaluation of ADAMTS17 in Chinese Shar-Pei with primary open-angle glaucoma, primary lens luxation, or both. AJVR 2018;79:98 [Web Reference]
Guandalini A. Epidemiology of ocular disorders presumed to be inherited in three small Italian dog breeds in Italy. Vet Ophthalmol 2017;Dec [Web Reference]
Gilger BC. Advanced Imaging of the Equine Eye. Vet Clin North Am Equine Pract 2017;Oct [Web Reference]
Belanger JM. Correlation of neuter status and expression of heritable disorders. Canine Genet Epidemiol 2017;4:6 [Web Reference]
Donzel E. Epidemiology and clinical presentation of canine cataracts in France: a retrospective study of 404 cases. Vet Ophthalmol 2017;20:131 [Web Reference]
Braus BK. Outcome of phacoemulsification following corneal and lens laceration in cats and dogs (20002010). Vet Ophthalmol 2017;20:4 [Web Reference]
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