Description    Mast Cell Tumors generally present as single or multiple skin lesions, sometimes accompanied by mast-cell leukemia. Cutaneous tumors range from soft and slow-growing to rapidly-enlarging and ulcerated. There can be sporadic appearance and disappearance of nonpigmented papules-to-wheals. Intestinal, ocular, visceral (e.g. hepatic and splenic), and laryngeal tumors also have been reported with or (rarely) without skin lesions. The visceral form is more common in cats than dogs and might be a separate form of the disease. Often associated with gastroduodenal ulcers in dogs.
Species   Canine, Feline
Signs   Abdominal distention, Abnormal upper airway breathing sounds, Alopecia, Anorexia, Ascites, Bloody stools, feces, hematochezia, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Cyanosis, Decreased amount of stools, absent feces, constipation, Dehydration, Diarrhea, Dullness, Dyspnea, Exercise intolerance, Exophthalmos, Fever, Forefoot swelling, Forelimb swelling, Head, face, ears, jaw, nose, nasal, swelling, Hematemesis, Hemorrhage of any body part or clotting failure, Hepatosplenomegaly, Hindfoot swelling, Hindlimb swelling, Increased respiratory rate, Internal abdominal mass, Laryngeal, tracheal, pharyngeal swelling, Lymphadenopathy, Melena or occult blood in feces, stools, Oral cavity, tongue swelling, Orbital, periorbital, periocular, conjunctival swelling, Pain on external abdominal pressure, Pale, Polydipsia, Polyuria, Pruritus, Reluctant to move, Skin crusts, Skin edema, Skin erythema, Skin hyperpigmentation, Skin pain, Skin papules, Skin plaque, Skin scales, Skin ulcer, Skin wheal, Sudden death, Swelling mass penis, prepuce, testes, scrotum, spermatic cord, Swelling skin or subcutaneous, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss
References   Moirano SJ. Association of prognostic features and treatment on survival time of dogs with systemic mastocytosis: A retrospective analysis of 40 dogs. Vet Compar Oncol 2018;Apr [Web Reference]
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