MAST CELL TUMOR, NEOPLASIA, MASTOCYTOMA, SYSTEMIC MASTOCYTOSIS IN DOGS AND CATS
 
Description    Mast Cell Tumors generally present as single or multiple skin lesions, sometimes accompanied by mast-cell leukemia. Cutaneous tumors range from soft and slow-growing to rapidly-enlarging and ulcerated. There can be sporadic appearance and disappearance of nonpigmented papules-to-wheals. Intestinal, ocular, visceral (e.g. hepatic and splenic), and laryngeal tumors also have been reported with or (rarely) without skin lesions. The visceral form is more common in cats than dogs and might be a separate form of the disease. Often associated with gastroduodenal ulcers in dogs.
 
Species   Canine, Feline
 
Signs   Abdominal distention, Abnormal upper airway breathing sounds, Alopecia, Anorexia, Ascites, Bloody stools, feces, hematochezia, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Cyanosis, Decreased amount of stools, absent feces, constipation, Dehydration, Diarrhea, Dullness, Dyspnea, Exercise intolerance, Exophthalmos, Fever, Forefoot swelling, Forelimb swelling, Head, face, ears, jaw, nose, nasal, swelling, Hematemesis, Hemorrhage of any body part or clotting failure, Hepatosplenomegaly, Hindfoot swelling, Hindlimb swelling, Increased respiratory rate, Internal abdominal mass, Laryngeal, tracheal, pharyngeal swelling, Lymphadenopathy, Melena or occult blood in feces, stools, Oral cavity, tongue swelling, Orbital, periorbital, periocular, conjunctival swelling, Pain on external abdominal pressure, Pale, Polydipsia, Polyuria, Pruritus, Reluctant to move, Skin crusts, Skin edema, Skin erythema, Skin hyperpigmentation, Skin pain, Skin papules, Skin plaque, Skin scales, Skin ulcer, Skin wheal, Sudden death, Swelling mass penis, prepuce, testes, scrotum, spermatic cord, Swelling skin or subcutaneous, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Vomiting or regurgitation, Weight loss
 
References   Johnson MC. Cytology of Skin Neoplasms. Vet Clin North Am Small Anim Pract 2017; 2017;47:85 [Web Reference]
Barker DA. Survey of UK-based veterinary surgeons` opinions on the use of surgery and chemotherapy in the treatment of canine high-grade mast cell tumour, splenic haemangiosarcoma and appendicular osteosarcoma. Vet Rec 2016;179:572 [Web Reference]
Miller RL. A retrospective review of treatment and response of high-risk mast cell tumours in dogs. Vet Comp Oncol 2016;14:361 [Web Reference]
Camus MS. Cytologic Criteria for Mast Cell Tumor Grading in Dogs With Evaluation of Clinical Outcome. Vet Pathol 2016;53:1117 [Web Reference]
Hart BL. Neutering of German Shepherd Dogs: associated joint disorders, cancers and urinary incontinence. Vet Med Sci 2016;2:191 [Web Reference]
Biller B. 2016 AAHA Oncology Guidelines for Dogs and Cats. JAAHA 2016;52:181 [Web Reference]
Grant J. Clinical response of masitinib mesylate in the treatment of canine macroscopic mast cell tumours. JSAP 2016;57:283 [Web Reference]
Worley DR. Nose and Nasal Planum Neoplasia, Reconstruction. Vet Clin N A Sm Anim Pract 2016;46:735 [Web Reference]
Mason S. Palliative care in small animal oncology. In Pract 2016;38:203 [Web Reference]
Sabattini S. Feline intestinal mast cell tumours: clinicopathological characterisation and KIT mutation analysis. J Fel Med Surg 2016;18:280 [Web Reference]
Elliott JW. Canine oral mucosal mast cell tumours. Vet Comp Oncol 2016;14:101 [Web Reference]
Copyright © 2016 Cornell University College of Veterinary Medicine