JUVENILE POLYARTERITIS SYNDROME, NECROTIZING VASCULITIS, IN DOGS
 
Description    Beagles and occasionally other breeds can develop a syndrome of recurrent pain and fever that persists for up to a week. The pain can be intense and diffuse or more localized in the shoulder, neck, hip or along the back. There can be associated neurologic deficits. There is periarteritis in the heart and meninges with subdural and extradural spinal-cord hemorrhage. There is often a neutrophilic pleocytosis of the CSF, combined with an inability to identify an infectious agent in the spinal fluid.
 
Species   Canine
 
Signs   Abnormal anal, perineal, tail reflexes, Abnormal hindlimb reflexes, Abnormal panniculus reflex, Abnormal proprioceptive positioning, Anorexia, Back pain, Conjunctival, scleral, injection, Conjunctival, scleral, redness, Constant or increased vocalization, Diarrhea, Dullness, Dyspnea, Fever, Forelimb lameness, Forelimb pain, Forelimb spasms, Generalized lameness or stiffness, Generalized weakness, Head, face, neck spasms, Hemiparesis, Hindlimb atrophy, Hindlimb hypoesthesia, Hindlimb lameness, Hindlimb pain, Hyperesthesia, Inability to stand, Increased respiratory rate, Kyphosis, Melena or occult blood in feces, stools, Muscle hypotonia, Pain on external abdominal pressure, Pain, chest, thorax, ribs, sternum, Pain, neck, cervical, throat, Pain, scrotum, Pain, testes, Paraparesis, Pelvic or hip pain, Reluctant to move, Skin edema, Skin pain, Stiffness or extended neck, Tachycardia, Tail weakness, Tail, anal hypoesthesia, Tetraparesis, Trembling, Underweight, poor condition, thin, emaciated, unthriftiness, ill thrift, Urinary incontinence, Weight loss
 
References   Hughes KL. Hemorrhage in the central canal of the cervical spinal cord in a coonhound diagnosed with canine juvenile polyarteritis (steroid responsive meningitis-arteritis). Can Vet J 2015;56:567 [Web Reference]
Swann JW. Histologic and clinical features of primary and secondary vasculitis: a retrospective study of 42 dogs (20042011). J Vet Diagn Invest 2015;27:4896 [Web Reference]
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