SUDDEN ACQUIRED RETINAL DEGENERATION SYNDROME IN DOGS, SARDS
 
Description    Sudden Acquired Retinal Degeneration Syndrome is: irreversible sudden or relatively sudden (over a period of less than 4 weeks) loss of vision; the absence of obvious retinal lesions; and an extinguished electroretinogram indicating a lack of photoreceptor function. The cause is unknown but is associated with apoptosis of photoreceptors of the retina. Usually a disease of adult dogs. Within weeks or months there can be retinal degeneration. In some dogs clinical signs are not limited to the eyes.
 
Species   Canine
 
Signs   Abnormal behavior, aggression, changing habits, Abnormal pupillary response to light, Abnormal retinal pigmentation, Abnormal retinal reflectivity, Blindness, Conjunctival, scleral, redness, Dullness, Dyspnea, Hepatosplenomegaly, Increased respiratory rate, Mydriasis, Overweight, Polydipsia, Polyphagia, Polyuria
 
References   Young WM. Clinical therapeutic efficacy of mycophenolate mofetil in the treatment of SARDS in dogs—a prospective open-label pilot study. Vet Ophthalmol 2018;Jan [Web Reference]
Leis ML. Sudden acquired retinal degeneration syndrome in western Canada: 93 cases. Can Vet J 2017;58:1195 [Web Reference]
Auten CR. Cofactors associated with Sudden Acquired Retinal Degeneration Syndrome: 151 dogs within a reference population. Vet Ophthalmol 2017;Aug [Web Reference]
Heller AR. Sudden acquired retinal degeneration in dogs: breed distribution of 495 canines. Vet Ophthalmol 2017;20:103 [Web Reference]
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