Advancing the health and well-being of animals and people

photo of Dr. Gregory Acland

Gregory M. Acland
Cornell University
College of Veterinary Medicine
Baker Institute for Animal Health
Hungerford Hill Rd.
Ithaca, NY 14853
P: (607) 256-5684
F: (607) 256-5608

Additional Resources

Baker Institute for Animal Health

Selected Publications

Kukekova AV, Temnykh SV, Johnson JL, Trut LN, Acland GM. Genetics of behavior in the silver fox. Mamm Genome.  2012. Feb;23(1-2): 164-77. Epub 2011 Nov 23.  Review. PMID: 22108806

Miyadera K, Acland GM, Aguirre GD. Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies. Mamm Genome. 2012 Feb;23(1-2): 40-61. Epub 2011 Nov 8. Review. PMID: 22065099

Berta Ál, Boesze-Battaglia K, Genini S, Goldstein O, O'Brien PJ, Szél Á, Acland GM, Beltran WA, Aguirre GD. Photoreceptor cell death, proliferation and formation of hybrid rod/S-cone photoreceptors in the degenerating STK38L mutant retina. PLoS One. 2011;6(9):e24074. Epuv 2011 Sep 30. PMID: 21980341

Kukekova AV, Johnson IL, Teiling C, Li L, Oskina IN, Kharlamova AV, Gulevich RG, Padte R, Dubreuil MM, Vladimirova AV, Shepeleva DV, Shikhevich SG, Sun Q, Ponnala L, Temnykh SV, Trut LN, Acland GM. Sequence comparison of prefrontal cortical brain transcriptome from a tame and an aggressive silver fox (Vulpes vulpes). BMC Genomics. 2011 Oct 3; 12:482. PMID: 21967120

Statham MJ, Trut LN, Sacks BN, Kharlamova AV, Oskina IN, Gulevich RG, Johnson JL, Temnykh SV, Acland GM, Kukekova AV. On the origin of a domesticated species: Identifying the parent population of Russian silver foxes (Vulpes vulpes). Biol J Linn Soc Lond. 2011 May; 103(1):168-175. PMID: 21625363

Kuznetsova T, Zangerl B, Goldstein O, Acland GM, Aguirre GD. Structural organization and expression pattern of the canine RPGRIP1 isoforms in retinal tissue. Invest Ophthalmol Vis Sci. 2011 May 6;52(6):2989-98. Print 2011 May. PMID: 21282582

Kukekova AV, Trut LN, Chase K, Kharlamova AV, Johnson JL, Temnykh SV, Oskina IN, Gulevich RG, Vladimirova AV, Klebanov S, Shepeleva DV, Shikhevich SG, Acland GM, Lark KG. Mapping Loci for fox domestication: deconstruction/reconstruction of a behavioral phenotype. Behav Genet. 2011 Jul;41(4):593-606. Epub 2010 Dec 14. PMID: 21153916

Zhou Z, Sheng X, Zhang Z, Zhao K, Zhu L, Guo G, Friedenberg SG, Hunter LS, Vandenberg-Foels WS, Hornbuckle WE, Krotscheck U, Corey E, Moise NS, Dykes NL, Li J, Xu S, Du L, Wang Y, Sandler J, Acland GM, Lust G, Todhunter RJ. Differential genetic regulation of canine hip dysplasia and osteoarthritis. PLoS One. 2010 Oct 11;5(10):e13219. PMID: 20949002

Goldstein O, Kukekova AV, Aguirre GD, Acland GM. Exonic SINE insertion in STK38L causes canine early retinal degeneration (erd). Genomics. 2010 Dec;96 (6):362-8. Epub 2010 Sep 29. PMID: 20887780

Goldstein O, Mezey JG, Boyko AR, Gao C, Wang W, Bustamante CD, Anguish LJ, Jordan JA, Pearce-Kelling SE, Aguirre GD, Acland GM. An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9. Mol Vix. 2010 Aug 11;16: 1549-69. PMID: 20806078

Goldstein O, Guyon R, Kukekova A, Kuznetsova TN, Pearce-Kelling SE, Johnson J, Aguirre GD, Acland GM. COL9A2 and COL9A3 mutations in canine autosomal recessive oculoskeletal dysplasia. Mamm Genome. 2010 Aug; 21(7-8): 398-408. Epub 2010 Aug 5. PMID: 20686772

Meurs KM, Mauceli E, Lahmers S, Acland GM, White SN, Lindblad-Toh K.  Genome-wide association identifies a deletion in the 3' untranslated region of striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy. Hum Genet. 2010 Sep;128(3): 315-24. Epub 2010 July 2. PMID: 20596727

Genini S, Zangerl B, Slavik J, Acland GM, Beltran WA, Aguirre GD. Transcriptional profile analysis of RPGRORF15 frameshift mutation identifies novel genes associated with retinal degeneration. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):6038-50. Epub 2010 Jun 23. PMID: 20574030

Komáromy AM, Alexander JJ, Rowlan JS, Garcia MM, Chiodo VA, Kaya A, Tanaka JC, Acland GM, Hauswirth WW, Aguirre GD. Gene therapy rescues cone function in congenitial achromatopsia.  Hum Mol Genet. 2010 Jul 1; 19(13): 2581-93. Epub 2010 Apr 8. Erratum in: Hum Mol Genet. 2011 Dec 15; 20 (24): 5024. PMID: 20378608

Beltran WA, Allore HG, Johnson E, Towle V, Tao W, Acland GM, Aguire GD, Zeiss CJ. CREB1/ATF1 activation in photoreceptor degeneration and protection. Invest Ophthalmol Vis Sci. 2009 Nov;50(11): 5355-63 Epub 2009 Jul 30. PMID: 19643965

Parker HG, VonHoldt BM, Quignon P, Margulies EH, Shao S, Mosher DS, Spady TC, Elkahloun A, Cargill M, Jones PG, Maslen CL, Acland GM, Sutter NB, Kuroki K, Bustamante CD, Wayne RK, Ostrander EA. An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. Science. 2009 Aug 21;325(5943):995-8 Epub 2009 Jul 16. PMID: 19608863