Dr. Stephen Barr
College of Veterinary Medicine
C3 534 CPC, Box 34
Ithaca, NY 14853
P: (607) 253-3043
F: (607) 253-3534
Publications in refereed journals:
Barr SC: Clinical features, therapy and epidemiology of Tiger Snake bite in dogs and cats. Aust Vet J 61:208-212, 1984.
Hamir AN, Sullivan ND, Barr SC: An outbreak of lead poisoning in dogs. Aust Vet J 62:21-23, 1985.
Barr SC: Pituitary tumour causing multiple endocrinopathies in a dog. Aust Vet J 62:127-129, 1985.
Friend SCE, Barr SC, Embury D: Fucosidosis in an English Springer Spaniel presenting as a malabsorption syndrome. Aust Vet J 62:415-419, 1985.
Barr SC, Lavelle RB, Harrigan K, Arundel J: Osleris (Filaroides) osleri in a dog. Aust Vet J 63:334-336, 1986.
Barr SC, Baker D, Markovits J: Trypanosomiasis in a dog with laryngeal paralysis. J Am Vet Med Assoc 188:1307-1309, 1986.
Barr SC, Eilts BE, Roy AF, Miller R: Brucella suis - Biotype 1 in a dog. J Am Vet Med Assoc 189:686-687, 1986.
Hamir AN, Sullivan ND, Handson PD, Barr SC: A comparison of calcium disodium ethylene diamine tetra-acetate (CaEDTA) by oral or subcutaneous routes as a treatment of lead poisoning in dogs. J Sm An Pract 27:39-43, 1986.
Jaynes JM, Burton CA, Barr SC, Jeffers GW, Julian GR, White KL, Enright FM, Klei TR, Laine RA: In vitro cytocidal effect of novel lytic peptides on Plasmodium falciparum and Trypanosoma cruzi. FASEB 2:2878-2883, 1988.
Barr SC, Simpson PM, Schmidt SP, Bunge MM, JM Authement, F Lozano: Chronic dilative myocarditis caused by Trypanosoma cruzi in two dogs. J Am Vet Med Assoc 195:1237-1241, 1989.
Barr SC, Dennis VA, Klei TR: Growth characteristics in axenic and cell cultures, protein profiles, and zymodeme typing of three Trypanosoma cruzi isolates from Louisiana mammals. J Parasitol 76:631-638, 1990.
Barr SC, Brown CC, Dennis VA, Klei TR: Infection of inbred mice with three Trypanosoma cruzi isolates from Louisiana mammals. J Parasitol 76:918-921, 1990.
Barr SC, Dennis VA, Klei TR: Serological and blood culture survey of four dog populations for Trypanosoma cruzi from south Louisiana. Am J Vet Res 52:570-573, 1991.
Barr SC: Canine American Trypanosomiasis. Comp Cont Ed Pract Vet 13:745-755, 1991.
Barr SC, Gossett K, Klei TR: Clinical, clinical pathological, and parasitological observations of experimental Chagas' disease in dogs produced by North American Trypanosoma cruzi isolates. Am J Vet Res 52:954-960, 1991.
Morris SA, Barr SC, Weiss L, Tanowitz H, Wittner M, Bilezikian JP: Myocardial b-adrenergic cyclase complex in a canine model of Chagasic Cardiomyopathy. Circulation Research 69:185-195, 1991.
Barr SC, Brown CC, Dennis VA, Klei TR: The lesions and prevalence of Trypanosoma cruzi in opossums and armadillos from south Louisiana. J Parasitol 77:624-627, 1991.
Barr SC, Dennis VA, Klei TR, Norcross NL: Antibody and lymphoblastogenic responses of dogs experimentally infected with Trypanosoma cruzi isolates from North American mammals. Vet Immuno Immunopath 29:267-283, 1991.
Center SA, Barr SC, Gould WJ, Hornbuckle WE, Randolph JF, Moise NS, Rebhun WC. The process of becoming Board certified. J Vet Intern Med 5:305-306, 1991.
Barr SC, Schmidt PS, Brown CC, Klei TR: Pathologic features of dogs inoculated with North American Trypanosoma cruzi isolates. Am J Vet Res 52:2033-2039, 1991.
Barr SC, Holmes RA, Klei TR: Electrocardiographic and echocardiographic features of trypanosomiasis in dogs inoculated with North American Trypanosoma cruzi isolates. Am J Vet Res 53:521-527, 1992.
Suess RP, Barr SC, Sacre BJ, French TW: Bone marrow hypoplasia in a feminized dog with a interstitial cell tumor. J Am Vet Med Assoc 200:1346-1348, 1992.
†*Barr SC, Bowman DD, Erb HN: Evaluation of two test procedures for the diagnosis of giardiasis in dogs. Am J Vet Res 53:2028-2031, 1992.
Barr SC, Ludders JW, Looney AL, Gleed RD, Erb HN: Platelet aggregation in dogs after sedation with acepromazine and atropine and during subsequent general anesthesia and surgery. Am J Vet Res 53:2067-2070, 1992.
Peterson EN, Barr SC, Gould WJ, Beck KA, Bowman DD: Use of fenbendazole for treatment of Crenosoma vulpis infection in a dog. J Am Vet Med Assoc 202:1483-1484, 1993.
†*‡Barr SC, Bowman DD, Heller RL, Erb HN: Efficacy of albendazole against giardiasis in dogs. Am J Vet Res 54:926-928, 1993.
*Barr SC, Bowman DD, Lyndsey PG, Barr MC: Trypanosoma manulis n. sp. from a Russian Pallas Cat Felis manul. J Euk Microbiol (previously J Protozool) 40:233-237, 1993.
Bowman DD, Darrigrand R, Frongillo M, Barr SC, Flanders J, Carbone L: Treatment of experimentally induced trichinosis in dogs and cats. Am J Vet Res 54:1303-1305, 1993.
Court EA, Earnest-Koon KA, Barr SC, Gould WJ: Malignant histiocytosis in a cat. JAm Vet Med Assoc 203:1300-1302, 1993.
Barr SC: Anti-heart tissue antibodies during experimental infections with pathogenic and non-pathogenic Trypanosoma cruzi isolates in dogs. International J Parasitol 23:961-967, 1993.
Barr SC, Bowman DD: Giardiasis of dogs and cats. Comp Cont Ed Pract Vet 16:603-610, 1994.
Barr SC, Bowman DD, Heller RL: Efficacy of fenbendazole against giardiasis in dogs. Am J Vet Res, 55:988-990, 1994.
† Abstracted in J Am Vet Med Assoc.
‡ Abstracted in International Vet Digest.
* Abstracted in Clinical Digest Updates.
Schermerhorn T, Barr SC, Stoffagen DA, Karen-Roth Y, Erb HN: Whole-blood platelet aggregation, buccal mucosa bleeding time, and serum cephalothin concentration in dogs receiving a presurgical antibiotic protocol. Am J Vet Res 55:1603-1607,1994.
Barr SC, Jamrosz GF, Hornbuckle WE, Bowman DD, Fayer R: Use of paromomycin for treatment of cryptosporidiosis in a cat. J Am Vet Med Assoc 205:1742-1743, 1994.
Barr SC, Bowman DD: Giardiasis in small animals. Bol Info Med Vet 8:16-20, 1995.
Pacioretty LM, Barr SC, Wei-Ping H, Gilmour RF: Reduction of the transient outward potassium current in a canine model of Chagas' Disease. Am J Physio 268:1258-1264, 1995.
†Barr SC, Van Beek O, Carlisle-Nowak M, Lopez JW, Kirchhoff LV, Allison N, Zajac A, de Lahunta A, Schlafer DH, Crandall WT: Trypanosoma cruzi infection in Walker hounds from Virginia. Am J Vet Res 56:1037-1044, 1995.
Toomey JT, Carlisle-Nowak M, Barr SC, Lopez JW, French TW, Scott FW, Hoose W, Dubey JP, Pizano S: Concurrent toxoplasmosis and feline infectious peritonitis in a cat. J Am Anim Hosp Assoc 31:425-428, 1995.
Barr SC, Rose D, Jaynes JM: Activity of lytic peptides against intracellular Trypanosoma cruzi amastigotes in vitro, and parasitemias in mice. J Parasitol 81:974-978, 1995.
Barr SC, Han WP, Andrews N, Lopez JW, Ball BA, Pannabecker TL, Gilmour RF: A factor from Trypanosoma cruzi induces repetitive cytosolic free Ca2+ transients in isolated primary canine cardiac myocytes. Infect & Immun 64:1770-1777, 1996.
McNamara PS, Barr SC, Erb HN: Hematologic, biochemical and hemostatic effects in dogs receiving cosequin for one month. Am J Vet Res 57:1390-1394, 1996.
Chen G, Barr SC, Walsh D, Rohde S, Brewer A, Bilezikian JP, Wittner M, Tanowitz H, Morris SA: Cardioprotective actions of verapamil on the b-adrenergic receptor complex in acute canine Chagas' Disease. J Mol Cell Cardiol 28:931-941, 1996.
Cote E, Barr SC, Allen C: Possible transmission of Blastomycosis dermatitidis via culture specimen. J Am Vet Med Assoc 210:479-480, 1997.
Han W, Barr SC, Pacioretty LM, Gilmour RF: Restoration of the transient outward potassium current by noradrenaline in chagasic canine epicardium. J Physiology (Lond.) 500:75-83, 1997.
Cote E, Barr SC, Allen C, Eaglefeather E: Blastomycosis in six dogs in New York state. J Am Vet Med Assoc 210:502-504, 1997.
†Moon PF, Barr SC, Erb HN: Effects of tromethamine buffer on coagulation variable and ionized calcium concentrations in dogs. Am J Vet Res 58:777-780, 1997.
Stokol T, Randolph JF, Nachbar S, Rodi C, Barr SC: Development of bone marrow toxicosis after albendazole administration in a dog and cat. J Am Vet Med Assoc 210:1753-1756, 1997.
Barr SC, Pannabecker TL, Chandler JS, Smith CA, Gilmour RF, Wasserman RH. Trypanosoma cruzi infection up-regulates expression of plasma membrane calcium pump protein and mRNA in canine cardiac myocytes. FASEB J 12:74, 1998.
† Abstracted in J Am Vet Med Assoc.
Idouraine A, Lippiello L, McNamara PS, Barr SC, McLaughlin RM: Cartilage stimulatory and Antiproteolytic activity is present in sera of dogs treated with a chondroprotective agent. Canine Prac 23:10-12, 1998.
Birnbaum N, Barr SC, Center SA, Schermerhorn T, Randolph JF, Simpson KW: Naturally acquired leptospirosis in 36 dogs: Serological and clinicopathological features. J Small An Prac 39:231-236, 1998.
Barr SC, Bowman DD, Frongello MM, Joseph S: Efficacy of a drug combination of praziquantel, pyrantel pamoate, and febantel against giardiasis in dogs. Am J Vet Res 59:1134-1136, 1998.
Lippiello L, Idouraine A, McNamara PS, Barr SC, McLaughlin RM: Cartilage stimulatory factor is present in sera of dogs treated with a chondroprotective agent. Canine Prac 24:18-19, 1999.
Toll J, Barr SC, Hickford FH: Acute water intoxication in a dog. J Vet Emerg Crit Care 9:19-24, 1999.
Phillips S, Barr SC, Dykes N, Katzenstein A, Scrivani P, Kraus M, Rishniw M, Valentine E: Bronchiolitis obliterans with organizing pneumonia in a dog. J Vet Int Med. 14:204-207, 2000
McNamara PS, Barr SC, Erb HN, Barlow LL: Hematologic, hemostatic, and biochemical effects in cats receiving an oral chrondroprotective agent for 30 days. Vet Therapeutics 1:108-117, 2000.
Kloc PA, Scrivani PV, Barr SC, Reiss K, Trotter EJ, Forest TW, Pool R: Vertebral angiomatosis in a cat. Vet Rad Ultrasound 42:42-45, 2001.
Jennings M, Center SA, Barr SC, Brandes D. Successful treatment of feline pancreatitis using an endoscopically placed gastrojejunostomy tube. J Am An Hosp Assoc 37:145-152, 2001.
Hickford FH, Barr SC, Erb HN: Effects of carprofen on hemostatic variables in dogs. Am J Vet Res 62:1642-1646, 2001.
Schantz PM, Jackson J, Steurer F, Rooney J, Breitschwerdt E, Barr SC. Evidence for direct dog-to-dog transmission of visceral leishmaniasis in the United States. J Am Soc Trop Med Hyg 65:421-422, 2001.
Barr SC. Leptospirosis: New Issues and Considerations. Comp Cont Ed Pract Vet 24:53-56, 2002.
Lindsey DS, Zajac AM, Barr SC. Leishmaniasis in American Foxhounds: An emerging zoonosis? Comp Cont Ed Pract Vet 24:304-312, 2002.
Palaniappan RUM, Chang YF, Jusuf SSD, Artiushin S, Timoney JF, McDonough SP, Barr SC, Divers TJ, Simpson KW, McDonough PL, Mohammed HO. Cloning and molecular characterization of an immunogenic LigA protein of Leptospira interrogans. Infect & Immun 70:5924-5930, 2002.
Wakshlag JJ, Kallfelz FA, Barr SC, Ordway GA, Haley NJ, Flaherty CE, Kelly RL, Altom EK, Lepine AJ, Davenport GM. The effect of exercise on skeletal muscle proteolysis: An investigation of the ubiquitin proteasome pathway and other metabolic markers. J Vet Therapeutics 3:215-225, 2003.
Barr SC, Linke RA, Janssen D, Guard CL, Smith MC, Daugherty CS, Scarlett JM. Detection of biofilm formation and nanobacteria under long-term cell culture conditions in serum samples from cattle, goats, cats, and dogs. Am J Vet Res 64:176-182, 2003.
Barr SC, Pannabecker TL, Gilmour RF, Chandler JS. Upregulation of cardiac cell plasma membrane Ca2+ pump in a canine model of Chagas’ disease. J Parasitol 89:381-384, 2003.
Teng CH, Barr SC, Chang YF. Cloning and characterization of putative zinc protease genes in Ehrlichia canis. DNA Sequence 14:109-121, 2003.
Barr SC, Warner K. Characterization of a serine protease activity in Sarcocystis neurona merozoites. J Parasitol 89:385-388, 2003.
Schatzberg SJ, Haley NJ, Barr SC, Parrish C, Summers BA, deLahunta A, Kornegay JN, Sharp NJH. Polymerase chain reaction amplification of parvoviral DNA from brains of dogs and cats with cerebellar hypoplasia. J Vet Int Med 17:538-544, 2003.
Wakshlag JJ, Barr SC, Ordway GA, Kallfelz F, Flaherty CE, Christensen BW, Nydam DV, Davenport GM. Effect of dietary protein on lean body wasting in dogs: Correlation between loss of lean mass and markers of proteasome dependent proteolysis. J An Phys Nutrition 87:408-420, 2003.
Schatzberg SJ, Haley NJ, Barr SC, deLahunta A, Olby N, Munana K, Sharp NJH. Use of a multiplex polymerase chain reaction assay in the antemortem diagnosis of toxoplasmosis and neosporosis in the central nervous system of cats and dogs. Am J Vet Res 64:1507-1513, 2003.
Glowaski MM, Moon-Massat PF, Erb HN, Barr SC. Effects of oxypolygelatin and dextran 70 on hemostatic variables in dogs. Vet Anaesth Analg 30:202-210, 2003.
Rishniw M, Barr SC, Simpson KW, Winand JN, Wootton JAM. Cloning and sequencing of the canine and feline cardiac troponin I genes. Am J Vet Res 65:53-58, 2004.
Wakshlag JJ, Cooper BJ, Wakshlag RR, Kallfelz FA, Barr SC, Nydam DV, Dimauro S. Biochemical evaluation of mitochondrial respiratory chain enzymes in canine skeletal muscle. Am J Vet Res 65:480-484, 2004.
Palaniappan RUM, Chang YF, Hassan F, McDonough SP, Pough M, Barr SC, Simpson KW, Mohammed HO, Shin S, McDonough P, Zuerner RL, Qu J, Roe B. Expression of leptospiral immunoglobulin-like protein by Leptospira interrogans and evaluation of its diagnostic potential in a kinetic ELISA. J Med Microbiol 53:975-984, 2004.
Schantz PM, Steurer FJ, Duprey ZH, Kurpel KP, Barr SC, Jackson JE, Beitschwerdt EB, Levy MG, Fox JC. Autochthonous visceral leishmaniasis in dogs in North America. J Am Vet Med Assoc 226:1316-1322, 2005.
Winkle TW, Center SA, Randolph JF, Barr SC, Erb HN. Evaluation of prognostic factors, survival rates, and treatment protocols for immune-mediated hemolytic anemia in dogs: 151 cases (1993-2002). J Am Vet Med Assoc 226:1869-1880, 2005.
Schatzberg SJ, Haley NJ, Barr SC, deLahunta A, Sharp NJH. Polymerase chain reaction screening for DNA viruses in paraffin-embedded brains from dogs with necrotizing meningoencephalitis, necrotizing leukoencephalitis, and granulomatous meningoencephalitis. J Vet Int Med 19:553-559, 2005.
Barr SC, McDonough PL, Scipioni-Ball R, Starr J. Serologic responses of dogs after vaccination with a commercial leptospirosis vaccine. Am J Vet Res 66:1780-1784, 2005.
Meseck EK, Njaa BL, Haley NJ, Park EH, Barr SC. Use of a multiplex polymerase chain reaction to rapidly differentiate Neospora caninum from Toxoplasma gondii in an adult dog with necrotizing myocarditis and myocardial infarct. J Vet Diag Invest 17:565-568, 2005.
Barr SC, Warner KL, Korneich BG, Piscitelli J, Wolfe A, Benet L, KcKerrow JH. A cysteine protease inhibitor protects dogs from cardiac damage during infection by Trypanosoma cruzi. Antimicrob Agents Chemother 49:5160-5161, 2005.
Schermerhorn T, Barr SC. Relationships between glucose, sodium and effective osmolality in diabetic dogs and cats. J Vet Emerg Critical Care 16:19-24, 2006.
Rishniw M, Barr SC, Simpson KW, Frongillo MF, Franz M, Dominguez-Alpizar JL. Discrimination between six species of canine microfilariae by a single polymerase chain reaction. Vet Parasitol 135:303-314, 2006.
Goldstein RE, Lin RC, Langston CE, Scrivani PV, Erb HN, Barr SC. Influence of infecting serogroup on clinical features of leptospirosis in dogs. J Vet Int Med 20:489-494, 2006.
Barr SC. Practical Guide to Tick-Borne Disease. North Am Vet Consults - Clinician's Brief 4:7-12, 2006.
Barr SC. Diagnostic tree for Fever. North Am Vet Consults - Clinician's Brief 4:14-15, 2006.
Chang YF, Chen CS, Palaniappan RUM, He H, McDonoug SP, Barr SC, Yan W, Faisal SM, Pan MJ, Chang CF. Immunogenicity of the recombinant leptospiral putative outer membrane proteins as vaccine candidates. Vaccine 25:8190-8197, 2007.
Vyhnal KK, Barr SC, Hornbuckle WE, Yeager AE, Wade SE, Frongillo MF, Simpson KW, Bowman DD. Eurytrema procyonis and pancreatitis in a cat. J Feline Med Surg 10:384-387, 2008.
Wilcox RS, Bowman DD, Barr SC, Euclid JM. Intestinal obstruction in a cat due to Taenia taeniaeformis. J Am Anim Hosp Assoc 45:93-96, 2009.
Yan W, Faisal SM, McDonough SP, Divers TJ, Barr SC, Chang CF, Pan MN, Chang YF. Immunogenicity and protective efficiency of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model. Microbes Infect 11:230-237, 2009.
Petersen CA, Barr SC. Leishmaniasis in North America: Emerging or newly recognized? Vet Clin North Am Small Anim Pract 39:1065-1074, 2009.
Barr SC. Canine Chagas’ disease (American trypanosomiasis) in North America. Vet Clin North Am Small Anim Pract 39:1055-1064, 2009.
Rishniw M, Pion PD, Herndon WE, Barr SC, de Lorimier LP, Rosenthal R, Katherman A, Vasilopulos R, Gunn-Christie R, Thamm D, Kude S, Speer B, Freshman J, Scherk M, Schmidt R, Datz C, Wolf A, Griffith D, Palmquist R, Harr K, Niessen S, Simpson K, Morgan R, Peterson M, Daugherty J. Improving reporting of clinical trials in Veterinary Medicine. J Vet Intern Med 24:799-800, 2010.
Barr SC, Rishniw M, Lynch M, Bohunicky B. Questions contents of clotrimazole solution. J Am Vet Med Assoc 236:163-164, 2010.
Houk AE, Goodwin DG, Zajac AM, Barr SC, Dubey JP, Lindsay DS. Prevalence of antibodies to Trypanosoma cruzi, Toxoplasma gondii, Encephalitozoon cuniculi, Sarcocystis neurona, Besnoitia darling, and Neospora caninum in North American opossums, Didelphis virginiana, from southern Louisiana. J Parasitol 96:1119-1122, 2010.
Sharpe KS, Center SA, Randolph JF, Brooks MB, Warner KL, Stokol T, Barr SC, Felippe MJ. Influence of treatment with ultralow-dose aspirin on platelet aggregation as measured by whole blood impedance aggregometry and platelet P-selectin expression in clinically normal dogs. Am J Vet Res 71:1294-1304, 2010.
Rosypal AC, Hill R, Lewis S, Barr SC, Valadas S, Gennari SM, Lindsay DS. Evaluation of a rapid immunochromatographic dipstick test for detection of antibodies to Trypanosoma cruzi in dogs experimentally infected with isolates obtained from opossums (Didelphis virginiana), armadillos (Dasypus novemcinctus), and dogs (Canis familiaris) from the United States. J Parasitol 97:140-143, 2011.
Goussev S, Barr SC. Vasculitis and myositis secondary to fluoxetine administration in a dog. J Am Vet Med Assoc (submitted Dec 2011).
Associate Editor, Small Animal Internal Medicine. Journal of Veterinary Internal Medicine. July 2001 – Jan 2005.
Editorial review board, Clinician Brief - NAVC. Jan 2003 – current.
Bowman DD, Hendrix CM, Lindsey DS, Barr SC: Feline Clinical Parasitology. Iowa State University Press. November 2001.
Bowman DD, Barr SC. Guide to Parasites of Dogs and Cats. Teton NewMedia, Jackson, Wyoming. July 2002.
Barr SC, Bowman DD. The 5-Minute Veterinary Consult Clinical Companion: Canine and Feline Infectious diseases and Parasitology. Blackwell Publishing, Ames, Iowa. January 2006.
Barr SC, Bowman DD. The 5-Minute Veterinary Consult Clinical Companion: Canine and Feline Infectious diseases and Parasitology. 2nd Edition. Wiley-Blackwell Publishing, Ames, Iowa. December 2011.
Books; Consultant Editor:
Barr SC: Consultant editor; Infectious diseases section. The 5 Minute Veterinary Consult (2nd Ed). LP Tilley, FWK Smith (eds), Lippincott, Williams and Wilkins, 2000.
Barr SC: Consultant editor; Infectious diseases section. The 5 Minute Veterinary Consult (3rd Ed). LP Tilley, FWK Smith (eds), Lippincott, Williams and Wilkins, 2003.
Barr SC: Consultant editor; Infectious diseases section. The 5 Minute Veterinary Consult (4th Ed). LP Tilley, FWK Smith (eds), Blackwell Publishing, 2008.
Barr SC: Guest Editor; Current topics in canine and feline infectious diseases. Veterinary Clinics of North America, small animal practice 40, Nov 2010.
Barr SC: Consultant editor; Infectious diseases section. The 5 Minute Veterinary Consult (5th Ed). LP Tilley, FWK Smith (eds), Wiley-Blackwell Publishing, 2011.