Briko the French Bulldog
Briko suffered with chronic bloody diarrhea for a full year. Her owners tried diet modifications and various drugs to treat the problem, but nothing helped. When Briko arrived at the Cornell University Hospital for Animals, defecating seemed painful and progressive weight loss had been noticed.
We performed a colonoscopy on Briko, which revealed a thickened, irregular colon. Endoscopic biopsies were characterized by severe chronic diffuse histiocytic, lymphoplasmacytic, and neutrophilic inﬂammation and ulceration.
We used Fluorescent in Situ Hybridization techniques to look for invasive bacteria and found that Briko had granulomatous colitis associated with E.coli. The bacteria were cultured from Briko’s colon and antimicrobial susceptibility testing was performed to guide our treatment plan. Briko’s colitis responded well to this treatment.
Although an uncommon type of inﬂammatory bowel disease, granulomatous colitis associated with E.coli is often found in young Boxers and French bulldogs, like Briko. Dogs with this disease require aggressive antimicrobial therapy for at least six weeks. Bacteria are increasingly implicated in inﬂammatory bowel disease and specialized techniques to enable their detection are available at Cornell.
Butch the English Bulldog
When Butch, an English bulldog, was referred to the Cornell University Hospital for Animals, his outlook was bleak. He was vomiting, regurgitating, and lethargic. And, his temperature was elevated to 106.9 degrees Fahrenheit. Presumptively diagnosed with gastrointestinal ulceration, Butch was admitted to our emergency clinic, literally ﬁghting for his life.
Once at Cornell, Butch was stabilized and transferred to the Internal Medicine Service where we conducted several tests. Butch had a tense uncomfortable abdomen and continued to regurgitate. In-depth investigation found no deﬁnitive evidence of intestinal perforation. Our team continued to provide medical care until he was stable enough to undergo endoscopy. The initial upper gastrointestinal endoscopy revealed moderate esophagitis, a diffusely thick stomach with multifocal punctate erosions, and more than 10 severe ulcers at the opening of the duodenum.
We gave Butch medicine to help his ulcers and esophagitis heal and administered an endocapsule - a capsule the size of a pill that contains a small camera - to determine if his intestinal damage was healing. The endocapsule revealed that the duodenal ulcers had healed, and Butch was sent home.