T H E D A V I S S O N L A B
The members of the Davisson Lab at Cornell University's Departments of Biomedical Sciences (College of Veterinary Medicine) and Cell & Developmental Biology (Weill Cornell Medical College) welcome you to our website. We are a diverse group of investigators gathered in the beautiful Finger Lakes region of Upstate New York and in the Upper East Side of Manhattan. As you journey through this site, you will see that our research, though wide-ranging, is centered on the common theme of establishing links between the renin-angiotensin system, oxidative stress and cardiovascular disease. We invite you to explore these pages to learn more about our lab and hope that you will become as intrigued with our work as we are!
Our research focuses on the basic mechanisms of function, control and signaling in the cardiovascular system in health and disease. Investigations employ the interdisciplinary approach of "functional genomics," an endeavor at the interface of classical physiology and molecular biology. Understanding the molecular mechanisms underlying hypertension, heart failure and the pregnancy-induced cardiovascular syndrome pre-eclampsia are the main focuses of our research efforts.
Recent News from the Davisson Lab
Congratulations to Jenny Sones who received her PhD diploma at the Cornell Commencement Recognition Event on Saturday, December 20, 2014. Congratulations Dr. Sones! 12/22/14
Congratulations to Jenny Sones, who successfully defended her Dissertation entitled, “Defects in periimplantation signaling contribute to adverse pregnancy outcomes in the BPH/5 mouse model of preeclampsia”. Way to go, Dr. Sones! 11/10/14
- Congratulations to Dr. Ana
Valbuena, postdoctoral associate in the Davisson Lab at Weill Cornell on receiving the Inigo Alvarez de Toledo Renal Foundation Award (FRIAT) presented by the Queen of Spain on October 27, 2014 for the paper “Oxysterol-induced soluble endoglin release and its involvement in hypertension” published in the journal Circulation. This study on the pathogenic mechanisms of preeclampsia was led by Dr. Carmelo Bernabeu from Centro de Investigaciones Biologicas, Madrid, Spain, while Ana was a PhD student. 11/10/14
- Jenny Sones,
graduate student in the Davisson Lab, was selected by the American Heart Association as a recipient of the “Best of AHA Specialty Conferences” award. Jenny’s abstract entitled “BPH/5 Pre-eclamptic Mice Have Increased Uterine Interleukin (IL)-5 and this is Associated with Decidual Natural Killer (dNK) Cell Loss at the Maternal-Fetal Interface Early in Pregnancy” and a second abstract entitled “Cox2 Inhibition During Decidualization Improves Fetal Growth Restriction in the BPH/5 Mouse Model of Preeclampsia” were both recognized among the top 10% of accepted abstracts in the AHA Specialty Conferences. Jenny will re-present both studies at the national AHA Scientific Sessions in Chicago, November 15-19, 2014. Abstracts in this session will be exposed to special international news media and will be covered in the AHA Scientific Sessions news breaks. Congratulations, Jenny! 10/20/14
- Jenny Sones, graduate student in the Davisson Lab, received a New Investigator Award at the 2014 American Heart Association Council for High Blood Pressure Research Meeting in San Francisco, CA in September. Jenny received this award for her abstract entitled “BPH/5 Pre-eclamptic Mice Have Increased Uterine Interleukin (IL)-5 and this is Associated with Decidual Natural Killer (dNK) Cell Loss at the Maternal-Fetal Interface Early in Pregnancy”. Congratulations, Jenny! 10/20/14
- Jenny Sones,
graduate student in the Davisson Lab, was invited to participate as one of three speakers at the Eunice Kennedy Shriver National Institute of Child Health and Human Development Health Equity Seminar Series, “Toward Understanding the Pathobiology of Preeclampsia and the Potential Underlying Mechanism of Vitamin D Involvement” held at the NIH Campus in Bethesda, MD on September 4, 2014. Jenny’s presentation was entitled “Defective Immunoregulatory and Peri-Implantation Events at the Maternal-Fetal Interface in BPH/5, a Mouse Model of Preeclampsia”. 10/20/14
- Julie Horwath, an undergraduate in Nutritional Sciences and Fred Dong, an undergraduate in Biological Sciences, both students in the Davisson Lab at Cornell-Ithaca have each been awarded the 2014 David S. Bruce Excellence in Undergraduate Research Awards by the American Physiological Society at the 2014 Experimental Biology Meeting on April 26-30, 2014 in San Diego, CA. This award has been established for outstanding undergraduate students who are presenting their research at the Experimental Biology Meeting and selection of awards is based on the quality of oral presentation of a poster to the David S. Bruce Award Selection Committee. Julie presented her poster entitled “Relief of endoplasmic reticulum stress in the brain subfornical organ rescues high fat diet-induced non-alcoholic fatty liver disease“ and Fred presented his poster entitled “Early surge in oxidative stress in the brain subfornical organ during angiotensin-II-induced hypertension". Congratulations Julie and Fred! 5/16/14
- Congratulations to Jeff Peterson and Sarah Grekin on the birth of their daughter Hannah Reese Peterson born on April 8, 2014 at 6:05am. Hannah weighed 5lbs. 13ozs. 4/10/14
Scott Butler, Research Support Specialist in the Davisson Lab for the past 7 years, has been recognized for his 20 years of dedicated service to Cornell University. Congratulations, Scott! 3/31/14
- Dr. Colin Young,
postdoctoral associate in the Davisson Lab at Cornell-Ithaca has been awarded the 2014 Dean Franklin Young Investigator Award by the American Physiological Society. This award recognizes a young investigator who is doing in vivo physiological research and is in the process of establishing an independent laboratory. It comes with a $20,000 grant from Data Sciences International. Colin will be attending the Experimental Biology 2014 Conference in San Diego, CA where he will present his work and receive this award at the annual APS Business Meeting being held on April 29, 2014. Congratulations, Colin! 3/27/14
- Jenny Sones, graduate student in the Davisson Lab at Cornell-Ithaca has been a selected by the Water and Electrolyte Section of the American Physiological Society to give a special oral presentation for her abstract entitled “Interleukin 15 contributes to decidual natural killer cell loss via interferon gamma during early pregnancy in the preeclamptic BPH/5 mouse model” at the Data Blitz Session during the 2014 Experimental Biology Conference in San Diego, CA on April 26, 2014. As a selected presenter, Jenny has also been invited to write a mini-review based on the topic of her presentation, which will be published in the American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. Dr. Heinrich Lob is a collaborator on these studies. Congratulations, Jenny! 3/27/14
- Julie Horwath,
an undergraduate in Nutritional Sciences and Fred Dong, an undergraduate in Biological Sciences, both students in the Davisson Lab at Cornell-Ithaca who work closely with postdoc Dr. Colin Young, have each been awarded the 2014 David S. Bruce Outstanding Undergraduate Abstract Award by the American Physiological Society. This award has been established for outstanding undergraduate students who are presenting their physiological research at the Experimental Biology Meeting. Julie will be presenting her poster entitled “Relief of endoplasmic reticulum stress in the brain subfornical organ rescues high fat diet-induced non-alcoholic fatty liver disease“ and Fred will be presenting his poster entitled “Early surge in oxidative stress in the brain subfornical organ during angiotensin-II-induced hypertension“ at the 2014 Experimental Biology Meeting on April 26-30, 2014 in San Diego, CA. In addition, Julie and Fred will each be presenting their studies in an oral session to compete for an additional award at the EB meeting. Way to go Julie and Fred! 3/27/14
Congratulations to Jenny and Ryan Sones on the birth of their son Hunter Francis Sones born on March 12, 2014 at 4:53pm. Hunter weighed 7lbs. 7ozs. and 19.5 inches long. 3/17/14
Congratulations to Colin Young and Catharine Clark on the birth of their daughter Kellan Grace Young born on December 7, 2013 at 12:40am. Kellan weighed 6lbs. 9ozs. 12/9/13
- Dr. Robin Davisson has been elected as a
Fellow of the American Association for the Advancement of Science (AAAS), announced in the November 29 issue of Science. The induction ceremony is February 15, 2014 in Chicago.
Cornell Chronicle Press Release November 25, 2013 http://www.news.cornell.edu/stories/2013/11/eight-faculty-named-aaas-fellows 12/9/13
students in the Davisson Lab at Cornell-Ithaca participated in the poster presentation at the 29th Annual Undergraduate Fall Research Forum hosted by the Cornell Undergraduate Research Board (CURB) on November 13, 2013. Catherine Isroff “Dysregulated estrous cycles and uterine inflammation before pregnancy is associated with BPH/5 mice, a spontaneous model of preeclampsia”; Julie Horwath “Brain endoplasmic reticulum stress mediates the development of non-alcoholic fatty liver disease”; Fred Dong “Interaction between oxidative and endoplasmic reticulum stress in brain subfornical organ during angiotensin-II-induced hypertension”. 11/18/13
- Dr. Allyn Mark, visiting faculty in the Davisson Lab at Cornell-WCMC is the recipient of the 2013 University of Iowa Carver College of Medicine Distinguished Mentor Award. This award honors faculty members whose distinguished careers have resulted in the mentoring of individuals who have gone on to have their own distinguished careers.
Dr. Davisson was honored to be one of two people who paid tribute to Dr. Mark during the ceremony. Congratulations, Allyn! 11/18/13
- Dr. Colin Young, postdoctoral associate in the Davisson Lab at Cornell-Ithaca was awarded a NIH/NHLBI K99Grant for his proposal entitled “Role of Central Neural NFkB and ER Stress in Obesity-Induced Hypertension”, starting August 8, 2013. Congratulations, Colin! 11/18/13
- Welcome to Dr. Christa Heyward who joined the Davisson Lab at Cornell-Ithaca on October 1, 2013 as a postdoctoral fellow. Christa received her PhD in 2011 in Cell and Molecular Biology from the University of Pennsylvania. In the Davisson Lab, she will investigate the immune contribution to the development of preeclampsia using the BPH/5 mouse model. 11/7/13
Archived-News From the Davisson Lab