skip to content


Comparative Mammalian Reproductive Endocrinology/Physiology, Aging and Behavior

My lab's principal area of interest is mammalian physiology and behavior, with a focus on the life history trade-offs associated with the timing of hormone secretion, reproductive effort, and aging. We perform integrative studies at the molecular, cellular, and organismal levels to elucidate the mechanisms that underlie reproductive aging.

My lab generally follows Krogh’s Principle: “For a large number of problems, there will be some animal of choice, or a few such animals, in which it can most conveniently be studied.” (1929).

Two questions that are presently being addressed with interesting animal models are:

1. How do long-lived female mammals maintain and establish an ovarian reserve that will last for the duration of their reproductive lives?

(Photo by Gil Wizen)

2. Can anti-Müllerian hormone (AMH) be used to optimize exotic animal breeding programs?

Profile photo of cheetah

Methods used:


Some other systems and questions we're investigating:

Dogs and Cats – How effective are AMH and progesterone as diagnostic tests for spay status and ovarian remnant syndrome?

Mice – Is Chlamydia muridarum (Cm) sexually transmitted, does Cm-induced tubal infertility increase mating frequency in females, and do females prefer to mate with infected or uninfected males?

Animal models previously investigated:

Spotted hyenas – Natural masculinization of female external genitalia

Siberian hamsters – Short day lengths delayed female reproductive aging

Syrian hamsters – Chronological, but not reproductive age, influenced female mate preference

Yellow-pine chipmunks – Hormones and the hormonal response to stressors varied across seasons