Introducing the Center for Reproductive Genomics:

Cornell University has established the Center for Reproductive Genomics, which will combine basic and clinical research in reproductive sciences on Cornell's Ithaca campus and at Weill Cornell Medical College (WCMC) in New York City, which has one of the country's leading fertility clinics. Infertility affects 10 to 15 percent of couples of childbearing age. The Center for Reproductive Genomics is on the web at http://reprogenomics.cornell.edu.

Our latest publications:

Morelli MA, Werling U, Edelmann W, Roberson MS, Cohen PE. Analysis of meiotic prophase I in live mouse spermatocytes. Chromosome Res. In press (2008)

Kan R., Sun X., Kolas N.K., Avdievich E., Kneitz B., Edelmann W., & Cohen P.E. Comparative Analysis of Meiotic Progression in Female Mice Bearing Mutations in Genes of the DNA Mismatch Repair Pathway. Biology of Reproduction. 78: 462–471 (2008)

Avdievich E., Reiss C., Scherer S.S., Jin B., Cohen P.E., Edelmann W. & Kneitz B. Distinct effects of an MLH1 ATPase mutation on MMR functions, cancer and meiosis. Proceedings of the National Academy of Sciences U.S.A. 105: 4247-4252 (2008)

Svetlanov A., Baudat F., Cohen P.E., and De Massy B. Distinct functions of MLH3 at recombination hot spots in the mouse. Genetics. 178: 1937- 1945 (2008).

Holmes R.J, & Cohen P.E. Small RNAs and RNAi pathways in meiotic prophase I. Chromosome Research 15(5):653-65 (2007).

Cohen, P.E., Pollack, S.E., Pollard, J.W. Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals. Endocrine Reviews 27(4):398-426 (2006).