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      Recent Publications

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  1. Morelli MA, Werling U, Edelmann W, Roberson MS, Cohen PE. Analysis of meiotic prophase I in live mouse spermatocytes. Chromosome Res. In press (2008) Download pdf

  2. Kan R., Sun X., Kolas N.K., Avdievich E., Kneitz B., Edelmann W., & Cohen P.E. Comparative Analysis of Meiotic Progression in Female Mice Bearing Mutations in Genes of the DNA Mismatch Repair Pathway. Biology of Reproduction. 78: 462–471 (2008) Download PDF

  3. Avdievich E., Reiss C., Scherer S.S., Jin B., Cohen P.E., Edelmann W. & Kneitz B. Distinct effects of an MLH1 ATPase mutation on MMR functions, cancer and meiosis. Proceedings of the National Academy of Sciences U.S.A. 105: 4247-4252 (2008) Download PDF

  4. Svetlanov A., Baudat F., Cohen P.E., and De Massy B. Distinct functions of MLH3 at recombination hot spots in the mouse. Genetics. 178: 1937- 1945 (2008). Download PDF

  5. Holmes R.J, & Cohen P.E. Small RNAs and RNAi pathways in meiotic prophase I. Chromosome Research 15(5):653-65 (2007). Download PDF

  6. Cohen P.E., Pollack S.E., Pollard J.W. Genetic analysis of chromosome pairing, recombination, and cell cycle control during first meiotic prophase in mammals. Endocrine Reviews 27(4):398-426 (2006). Download PDF

  7. Li Z., Peled J.U., Zhao C., Svetlanov A., Ronai D., Cohen P.E., Scharff M.D. A role for Mlh3 in somatic hypermutation. DNA Repair (Amst). 5(6):675-82 (2006). Download PDF

  8. *Kolas N.K., *Svetlanov A., Lenzi M., Smith J., Macaluso F.P., Greally J.M., Edelmann W., Liskay R.M., Lipkin S.M., and Cohen P.E. Distinct functions of MutL homologs in reciprocal recombination and gene conversion in mammalian meiosis. * These authors contributed equally to this work. Journal of Cell Biology 171(3): 447-458 (2005). Download PDF

  9. *Morelli M.A. and Cohen P.E. Not all germ cells are created equal: aspects of sexual dimorphism in mammalian meiosis [Review]. Reproduction. 130(6):761-81 (2005). Download PDF

  10. Lenzi M.L., Smith J., Snowden T., Kim M., Fishel R., Poulos B.K., and Cohen P.E. Extreme Heterogeneity in the Molecular Events Leading to the Establishment of Chiasmata during Meiosis I in Human Oocytes. American Journal of Human Genetics 76: 112-127 (2005). Download PDF

  11. Kolas N.K. and Cohen P.E. Novel and diverse functions of the DNA mismatch repair family in mammalian meiosis and recombination [review]. Cytogenetic and Genome Research 107: 216-231 (2004). Download PDF

  12. Svetlanov A. and Cohen P.E. Mismatch repair proteins, meiosis, and mice: understanding the complexities of mammalian meiosis [review]. Experimental Cell Research 296(1): 71-79 (2004). Front cover article. Download PDF

  13. *Crackower M.A., *Kolas N.K., Noguchi J., Carao R., Kikuchi K., Kaneko H., Kobayashi E., Kawai Y., Kozieradzki I., Landers R., Mo R., Hui C.C., Nieves E., Cohen P.E., Osborne L.R., Wada T., Kunieda T., Moens P.B. and Penninger J.M. Essential role of Fkbp6 in male fertility and homologous chromosome pairing in meiosis. *These authors contributed equally to this work. Science 2003 300: 1291-1295 (2003). Download PDF

  14. Wei K., Clark A.B., Wong E., Kane M.F., Mazur D.J., Parris T., Kolas N.K., Russell R., Hou H., Kneitz B., Yang G., Kunkel T.A., Kolodner R.D., Cohen P.E. and Edelmann W. Inactivation of Exonuclease I in mice results in DNA mismatch repair defects, increased cancer susceptibility and male and female sterility. Genes & Development 2003 17: 603-614 (2003). Download PDF

  15. Lipkin S.M., Moens P.B., Wang V., Lenzi M., Shanmugarajah D., Gilgeous A., Thomas J., Cheng J., Touchman J.W., Green E.D., Schwartzberg P., Collins F.S. and Cohen P.E. Meiotic arrest and aneuploidy in MLH3-deficient mice. Nature Genetics 31(4): 385-390 (2002). Download PDF

  16. Moens P.B., Kolas N.K., Tarsounas M., Marcon E., Cohen P.E. and Spyropoulos B. The time course and localization of recombination-related proteins at meiosis in the mouse conform to models that can resolve the early DNA-DNA interactions without reciprocal recombination. Journal of Cell Science 115: 1611-1622 (2002). Download PDF

  17. Cohen P.E., Zhu L., Nishimura K., & Pollard J.W. Colony stimulating factor-1 (CSF-1) regulation of neuroendocrine pathways that control gonadal function in mice. Endocrinology 143: 1413-1422 (2002). Download PDF

  18. Cohen P.E. & Pollard J.W. Regulation of meiotic recombination and prophase I progression in mammals [review]. BioEssays 23:996-1009 (2001). Download PDF

  19. Zindy F., Den Besten W., Chen B., Rehg J.E., Latres E., Barbacid M., Pollard J.W., Sherr C.J., Cohen P.E., & Roussel M.F. Control of Spermatogenesis in Mice by the Cyclin D-Dependent Kinase Inhibitors p18 Ink4c and p19 Ink4d. Molecular & Cellular Biology 31:3244-3255 (2001). Download PDF

  20. *Kneitz B., *Cohen P.E., Avdievich E., Zhu L., Kane M.F., Hou H., Kolodner R.D., Pollard J.W., Kucherlapati R. & Edelmann W MutS homolog 4 (MSH4) localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. *These authors contributed equally to this work. Genes and Development 14: 1085-1097 (2000). Download PDF

  21. *Edelmann W., *Cohen P.E., Kneitz B., Winand N., Heyer J., Kolodner R., Pollard J.W. & Kucherlapati R. Mammalian MutS homolog 5 is required for chromosome pairing in meiosis. *These authors contributed equally to this work. Nature Genetics 21: 123-127 (1999). Download PDF

  22. Cohen P.E., Nishimura K., Zhu L. & Pollard J.W. Macrophages: Important accessory cells for reproduction [review]. Journal of Leukocyte Biology 66: 765-772 (1999). Front cover article. Download PDF

  23. Cohen P.E. & Pollard J.W. Normal sexual function in male mice lacking a functional type I interleukin-1 receptor. Endocrinology -139: 815-818 (1998). Download PDF

  24. Cohen P.E., Zhu L. & Pollard J.W. Absence of colony stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice disrupts estrous cycles and ovulation. Biology of Reproduction 56: 110-119 (1997).

  25. Pollard J.W., Dominguez M.G., Mocci S., Cohen P.E. & Stanley E.R. Effect of the colony stimulating factor-1 (CSF-1) null mutation, osteopetrotic (csfmop), on the distribution of macrophages in the male reproductive tract. Biology of Reproduction 56: 1290-1300- (1997).

  26. Cohen P.E., Hardy M.P. & Pollard J.W. CSF-1 plays a major role in the development of reproductive function in male mice. Molecular Endocrinology 11: 1636-1650 (1997). Download PDF

  27. Edelmann W., Yang K., Umar A., Heyer J., Lau K., Fan K., Liedtke W., Cohen P.E., Kane M.F., Lipford J.R., Yu N., Crouse G., Pollard J.W., Kunkel T., Lipkin M., Kolodner R. & Kucherlapati R. Mutation in the mismatch repair gene MSH6 causes cancer susceptibility. Cell 91: 467-477 (1997). Download PDF

  28. Nierras C.R., Horig H., Puech A., Cohen P.E., Pavelka M., & Pixley F.J. A survey of the postdoctoral population at Albert Einstein College of Medicine identifies a need for better mentoring. The Einstein Quarterly Journal of Biology and Medicine 14: 30-38 (1997).

  29. Cohen P.E., Chisholm O., Arceci R.J., Stanley E.R. & Pollard J.W. Absence of colony stimulating factor-1 in osteopetrotic (csfmop/csfmop) mice results in male fertility defects. Biology of Reproduction 55: 310-317 (1996).

  30. Cohen P.E. & Pollard J.W. Cytokines and growth factors in reproduction. In: Reproductive Immunology (Bronson R.A., Alexander N.J., Anderson D., Branch D.W., & Kutteh W.H., editors). Blackwell Science, Cambridge, MA. Chapter 3, pages 52-102 (1996).

  31. Edelmann W., Cohen P.E., Kane M., Lau K., Morrow B., Bennett S., Umar A., Kunkel T., Cattoretti G., Chaganti R., Pollard J.W., Kolodner R.D. & Kucherlapati R. Meiotic pachytene arrest in MLH-1-deficient mice. Cell 85: 1125-1134 (1996). Download PDF

  32. Milligan S.R., Cohen P.E. & Finn C.A. The minimum requirements for oestradiol to induce uterine sensitivity for implantation and decidualization in mice. Human Reproduction 10: 1502-1506 (1995).

  33. Cohen P.E. & Pollard J.W. Use of the osteopetrotic mouse for studying macrophages in the reproductive tract. In: Immunobiology of Reproduction (J.S. Hunt, editor). Springer-Verlag, New York. Chapter 8, pages 104-122 (1994).

  34. Milligan, S.R. and Cohen P.E. Silastic implants for delivering physiological concentrations of progesterone to mice. Reproduction, Fertility & Development 99: 219-223 (1993).

  35. Cohen P.E. & Milligan S.R. Silastic implants for delivery of oestradiol to mice. Journal of Reproduction and Fertility 99: 219-223 (1993).



Last Update June 4, 2008