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Simpson Lab Publications


This page summarizes the publications generated by the Simpson Lab



Simpson lab publications

Inflammatory bowel disease

Mansfield, C.S., James, F.E., Craven, M., Davies, D.R., O'Hara, A.J., Nicholls, P.K., Dogan, B., MacDonoug, S.P., Simpson, K.W. Remission of histiocytic ulcerative colitis in Boxer dogs correlates with eradication of invasive intramucosal E. Coli. J. Vet. Intern. Med. 23, 964-969. pdf

Baumgart, M., Dogan, B., Rishniw, M., Weitzman, G., Bosworth, B., Yantiss, R., Orsi, R.H., Wiedmann, M., McDonough, P., Kim, S.G., Berg, D., Schukken, Y., Scherl, E., Simpson, K.W., 2007. Culture Independent Analysis of Ileal Mucosa Reveals a Selective Increase in Invasive Escherichia Coli of Novel Phylogeny Relative to Depletion of Clostridiales in Crohn's Disease Involving the Ileum. ISME J. 1, 403-418. pdf

Simpson, K.W., Dogan, B., Rishniw, M., Goldstein, R.E., Klaessig, S., McDonough, P.L., German, A.J., Yates, R.M., Russell, D.G., Johnson, S.E., Berg, D.E., Harel, J., Bruant, G., McDonough, S.P., Schukken, Y.H., 2006. Adherent and Invasive Escherichia Coli is Associated with Granulomatous Colitis in Boxer Dogs. Infect. Immun. 74, 4778-4792. pdf

Janeczko, S., Atwater, D., Bogel, E., Greiter-Wilke, A., Gerold, A., Baumgart, M., Bender, H., McDonough, P.L., McDonough, S.P., Goldstein, R.E., Simpson, K.W., 2008. The Relationship of Mucosal Bacteria to Duodenal Histopathology, Cytokine mRNA, and Clinical Disease Activity in Cats with Inflammatory Bowel Disease. Vet. Microbiol. 128, 178-193. pdf

Smith, A.A., Posner, L.P., Goldstein, R.E., Ludders, J.W., Erb, H.N., Simpson, K.W., Gleed, R.D., 2004. Evaluation of the Effects of Premedication on Gastroduodenoscopy in Cats. J. Am. Vet. Med. Assoc. 225, 540-544. pdf

Simpson, K.W., Fyfe, J., Cornetta, A., Sachs, A., Strauss-Ayali, D., Lamb, S.V., Reimers, T.J., 2001. Subnormal Concentrations of Serum Cobalamin (Vitamin B12) in Cats with Gastrointestinal Disease. J. Vet. Intern. Med. 15, 26-32. pdf


Jergens, A.E., Pressel, M., Crandell, J., Morrison, J.A., Sorden, S.D., Haynes, J., Craven, M., Baumgart, M., Simpson, K.W., 2009. Fluorescence in Situ Hybridization Confirms Clearance of Visible Helicobacter Spp. Associated with Gastritis in Dogs and Cats. J. Vet. Intern. Med. 23, 16-23. pdf

Recordati, C., Gualdi, V., Tosi, S., Facchini, R.V., Pengo, G., Luini, M., Simpson, K.W., Scanziani, E., 2007. Detection of Helicobacter Spp. DNA in the Oral Cavity of Dogs. Vet. Microbiol. 119, 346-351. pdf

Greiter-Wilke, A., Scanziani, E., Soldati, S., McDonough, S.P., McDonough, P.L., Center, S.A., Rishniw, M., Simpson, K.W., 2006. Association of Helicobacter with Cholangiohepatitis in Cats. J. Vet. Intern. Med. 20, 822-827. pdf

Priestnall, S.L., Wiinberg, B., Spohr, A., Neuhaus, B., Kuffer, M., Wiedmann, M., Simpson, K.W., 2004. Evaluation of "Helicobacter Heilmannii" Subtypes in the Gastric Mucosas of Cats and Dogs. J. Clin. Microbiol. 42, 2144-2151. pdf

Straubinger, R.K., Greiter, A., McDonough, S.P., Gerold, A., Scanziani, E., Soldati, S., Dailidiene, D., Dailide, G., Berg, D.E., Simpson, K.W., 2003. Quantitative Evaluation of Inflammatory and Immune Responses in the Early Stages of Chronic Helicobacter Pylori Infection. Infect. Immun. 71, 2693-2703. pdf

Simpson, K.W., Strauss-Ayali, D., Straubinger, R.K., Scanziani, E., McDonough, P.L., Straubinger, A.F., Chang, Y.F., Esteves, M.I., Fox, J.G., Domeneghini, C., Arebi, N., Calam, J., 2001. Helicobacter Pylori Infection in the Cat: Evaluation of Gastric Colonization, Inflammation and Function. Helicobacter 6, 1-14. pdf

Strauss-Ayali, D., Scanziani, E., Deng, D., Simpson, K.W., 2001. Helicobacter Spp. Infection in Cats: Evaluation of the Humoral Immune Response and Prevalence of Gastric Helicobacter Spp. Vet. Microbiol. 79, 253-265. pdf

Neiger, R., Simpson, K.W., 2000. Helicobacter Infection in Dogs and Cats: Facts and Fiction. J. Vet. Intern. Med. 14, 125-133. pdf

Simpson, K.W., Strauss-Ayali, D., Scanziani, E., Straubinger, R.K., McDonough, P.L., Straubinger, A.F., Chang, Y.F., Domeneghini, C., Arebi, N., Calam, J., 2000. Helicobacter Felis Infection is Associated with Lymphoid Follicular Hyperplasia and Mild Gastritis but Normal Gastric Secretory Function in Cats. Infect. Immun. 68, 779-790. pdf

Simpson, K.W., McDonough, P.L., Strauss-Ayali, D., Chang, Y.F., Harpending, P., Valentine, B.A., 1999. Helicobacter Felis Infection in Dogs: Effect on Gastric Structure and Function. Vet. Pathol. 36, 237-248.

Simpson, K.W., Strauss-Ayali, D., McDonough, P.L., Chang, Y.F., Valentine, B.A., 1999. Gastric Function in Dogs with Naturally Acquired Gastric Helicobacter Spp. Infection. J. Vet. Intern. Med. 13, 507-515.

Cornetta, A.M., Simpson, K.W., Strauss-Ayali, D., McDonough, P.L., Gleed, R.D., 1998. Use of a [13C]Urea Breath Test for Detection of Gastric Infection with Helicobacter Spp in Dogs. Am. J. Vet. Res. 59, 1364-1369

Strauss-Ayali, D., Simpson, K.W., 1999. Gastric Helicobacter Infection in Dogs. Vet. Clin. North Am. Small Anim. Pract. 29, 397-414.

Strauss-Ayali, D., Simpson, K.W., Schein, A.H., McDonough, P.L., Jacobson, R.H., Valentine, B.A., Peacock, J., 1999. Serological Discrimination of Dogs Infected with Gastric Helicobacter Spp. and Uninfected Dogs. J. Clin. Microbiol. 37, 1280-1287.



Sekis, I., Ramstead, K., Rishniw, M., Schwark, W.S., McDonough, S.P., Goldstein, R.E., Papich, M., Simpson, K.W., 2009. Single-Dose Pharmacokinetics and Genotoxicity of Metronidazole in Cats. J. Feline Med. Surg. 11, 60-68. pdf

Kiselow, M.A., Rassnick, K.M., McDonough, S.P., Goldstein, R.E., Simpson, K.W., Weinkle, T.K., Erb, H.N., 2008. Outcome of Cats with Low-Grade Lymphocytic Lymphoma: 41 Cases (1995-2005). J. Am. Vet. Med. Assoc. 232, 405-410. pdf

Recordati, C., Radaelli, E., Simpson, K.W., Scanziani, E., 2008. A Simple Method for the Production of Bacterial Controls for Immunohistochemistry and Fluorescent in Situ Hybridization. J. Mol. Histol. 39, 459-462.

Dogan, B., Klaessig, S., Rishniw, M., Almeida, R.A., Oliver, S.P., Simpson, K., Schukken, Y.H., 2006. Adherent and Invasive Escherichia Coli are Associated with Persistent Bovine Mastitis. Vet. Microbiol. 116, 270-282. pdf

McDonough, P.L., Simpson, K.W., 1996. Diagnosing Emerging Bacterial Infections: Salmonellosis, Campylobacteriosis, Clostridial Toxicosis, and Helicobacteriosis. Semin. Vet. Med. Surg. (Small Anim) 11, 187-197.

Simpson, K.W., 2001. The Emergence of Feline Pancreatitis. J. Vet. Intern. Med. 15, 327-328. pdf

Simpson, K.W., Rishniw, M., Bellosa, M., Liotta, J., Lucio, A., Baumgart, M., Czarnecki-Maulden, G., Benyacoub, J., Bowman, D., 2009. Influence of Enterococcus Faecium SF68 Probiotic on Giardiasis in Dogs. J. Vet. Intern. Med. pdf


Contact: Simpson Laboratory, VMC 2013, Cornell University, Tower Road, Ithaca, NY 14853-6401.
Tel: 607-253-3567; fax: 607-253-3289.


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College of Veterinary Medicine - Ithaca, New York 14853-6401
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