Mouse  

Department of Microbiology and Immunology


Microbiology and Immunology

College of Veterinary Medicine
Cornell University
C5 181 VMC
Ithaca, NY 14853-6401

phone: 607-253-3400
fax: 607-253-3384

Email: M & I

Faculty by Research Area

The faculty in the Department of Microbiology and Immunology conduct research in the following areas:

 

 

 

Russell Bacterial PathogenesisBacterial Pathogenesis

The bacteriologists in the department focus their research on the strategies employed by pathogens that mediate an intracellular infection. These pathogens include Chlamydia, Mycobacterium, and Listeria. Research involves analysis of both bacterial effectors and the response of the host cell.

Faculty members in this area:

Paul Bowser

Infectious and non-infectious diseases of fish, pathogenesis of important bacterial pathogens of cultured and wild fish, evaluation of new therapeutic compounds for use in cultured food fish.

Rodman Getchell Molecular diagnostics and emerging diseases of fish; Target animal safety studies for new aquaculture therapeutants and chemicals
Hélène Marquis Pathogenesis of Listeria monocytogenes, mechanisms of regulation of specific virulence factors.
David Russell The biology of intracellular infection, with emphasis on Mycobacteria.
Brian VanderVen Physiology of the intracellular pathogen M. tuberculosis

 

Related program:

Program in Bacterial Pathogenesis

 

Whittaker Molecular VirologyMolecular Virology

The department has a broad-reaching program in virology covering viral infections of animals and humans. Research involves basic mechanisms of infection and propagation, the induction of disease, and the biology of viral infections in both farm animals and wildlife. Viral infections studied include avian flu, avian and equine herpes viruses, canine parvovirus, reovirus and the retroviruses of fish.

Faculty members in this area:

Joel Baines Molecular biology and biochemistry of herpesvirus assembly, envelopment, and cellular exit. Herpesvirus neurovirulence. Cell biology of herpesvirus induced changes in cultured cells.
Paul Bowser Infectious and non-infectious diseases of fish, pathogenesis of retrovirus-caused tumors of fish, pathogenesis of rhabdoviral infections in fish, evaluation of new therapeutic compounds for use in cultured food fish.
Rodman Getchell Molecular diagnostics and emerging diseases of fish; Target animal safety studies for new aquaculture therapeutants and chemicals
James Casey Eukaryotic gene regulation, oncogenic transformation, viral replication, viral pathogenesis, toxicology.
John Parker Cell biology, biochemistry and molecular biology of mammalian orthoreovirus-host cell interactions. Use of reoviruses as oncotherapeutic agents.
Colin Parrish Structure and function of canine parvovirus, crystallography, virus assembly, mechanism of host cell invasion.
Gerlinde Van de Walle Virus-natural host models to study herpesvirus pathogenesis with an emphasis on epigenetic dysregulation mechanisms in infected cells; adult stem cell biology
Gary Whittaker Endocytosis of influenza virus, structure-function studies on influenza HA, entry of coronaviruses and rhabdoviruses into host cells.
Kui Yang Mechanism of herpes simplex virus DNA cleavage and packaging and novel anti-herpes therapy

 

Related program:

Program in Virology

 

Bowman ParasitologyParasitology

The parasitologists in the department study the interface of the pathogen and host at the level of the host's immune response. This research focuses on the nature of the protective immune response and how the pathogen modulates the host response to ensure its success. The parasites studied include both protozoan and helminth pathogens: Cryptosporidium, Icthyophthirius, Leishmania, Schistosoma, Toxoplasma, and Trichomonas.

Faculty members in this area:

Judith Appleton Mucosal immunity in the intestinal tract, specifically intestinal immunity expressed against parasitic nematodes.
Dwight Bowman Soil transmitted parasites, parasites of wildlife, biosurveillance.
Paul Bowser Infectious and non-infectious diseases of fish, pathogenesis of parasites of cultured and wild fish, evaluation of new therapeutic compounds for use in cultured food fish.
Donna Cassidy-Hanley Infectious and non-infectious diseases of fish;Emerging pathogens of fish
Ted Clark Biology of the parasitic protist Ichthyophthirius multifilis (Ich), fish immunology, vaccine development.
Eric Denkers Immunity to the intracellular protozoan parasite Toxoplasma gondii.
Rodman Getchell Molecular diagnostics and emerging diseases of fish; Target animal safety studies for new aquaculture therapeutants and chemicals

 

ImmunologyImmunology

In addition to infection immunology, several investigators in the department research basic immune function, ranging from sensing of the innate immune system to developmental biology of the immune system and the effects of environmental toxins on immune function.

Faculty members in this area:

Douglas Antczak Pregnancy immunology; immunogenetics; equine immunology.
Judith Appleton Mucosal immunity in the intestinal tract, specifically intestinal immunity expressed against parasitic nematodes.
Avery August Immune cell activation and signaling in development, response to infection and respiratory inflammation.
Margaret Bynoe The molecular basis of antigen induced immune suppression and the modulation of the innate immune system response in immunity against cancer.
Donna Cassidy-Hanley Infectious and non-infectious diseases of fish;Emerging pathogens of fish
Ted Clark Biology of the parasitic protist Ichthyophthirius multifilis (Ich), fish immunology, vaccine development.
Eric Denkers Immunity to the intracellular protozoan parasite Toxoplasma gondii.
Rodney Dietert Genetic regulation of macrophage function; immunotoxicity.
Cynthia Leifer Understanding innate immunity from the inside out: Toll-like receptors, signaling, dendritic cells, and controlling microbial infection.
Brian Rudd

Developmental immunology; host response to infection

David Russell The biology of intracellular infection, with emphasis on Mycobacteria.