Dr. Marquis is a professor of Microbiology and Immunology. She received a doctorate degree in Veterinary Medicine from the University of Montréal in Canada and was awarded a Ph.D. in Veterinary Microbiology from Texas A&M University for her studies on the outer membrane proteins of Brucella spp. with Dr. Thomas Ficht. She was a postdoctoral fellow in the laboratory of Dr. Daniel Portnoy at the University of Pennsylvania, working on the pathogenesis of Listeria monocytogenes. In 1997, she assumed a position of assistant professor in the Department of Microbiology at the University of Colorado School of Medicine. She moved to Cornell University in July 2001.
Dr. Marquis is a member of the following Graduate Fields:
Comparative Biomedical Sciences
O’Neil, H.S., B.M. Forster, K.L. Roberts, A.J. Chambers, A.P. Bitar, and H. Marquis. 2009. The propeptide of the metalloprotease of Listeria monocytogenes controls compartmentalization of the zymogen during intracellular infection. J. Bacteriol. 191:3594-3603.
Zemansky, J., B.C. Kline, J.J. Woodward, J.H. Leber, H. Marquis, and D.A. Portnoy. 2009. Development of a mariner-based transposon and identification of Listeria monocytogenes determinants, including the peptidyl-prolyl isomerase PrsA2, that contribute to its hemolytic activity. J. Bacteriol. 191:3950-3964.
Xayarath, B., H. Marquis, G. C. Port, and N. E. Freitag. 2009. Listeria monocytogenes CtaP is a multifunctional cysteine transport-associated protein required for bacterial pathogenesis. Mol Microbiol. 74:956-973.
Slepkov, E.R., A. Pavinski Bitar, and H. Marquis. 2010. Differentiation of propeptide residues regulating the compartmentalization, maturation and activity of the broad-range phospholipase C of Listeria monocytogenes. Biochem. J. 432:557-563.
Forster, B.M., A. Pavinski Bitar, E.R. Slepkov, K.J. Kota, H. Sondermann, and H. Marquis. 2011. The metalloprotease of Listeria monocytogenes is regulated by pH. J. Bacteriol. 193:5090-5097.
Forster, B.M., J. Zemansky, D.A. Portnoy, and H. Marquis. 2011. The post-translocation chaperone PrsA2 regulates the maturation and secretion of Listeria monocytogenes proprotein virulence factors. J. Bacteriol. 193:5961-5970.
Foster, B.M. and H. Marquis. 2012. Protein transport across the cell wall of monoderm Gram-positive bacteria. Mol. Microbiol. 84:405-413.
Forster, B.M., A. Pavinski Bitar, and H. Marquis. 2014. A non-catalytic histidine residue influences the function of the metalloprotease of Listeria monocytogenes. Microbiol. 160:142-148.
Blank, B.S., D.S. Abi Abdallah, J.J. Park, E.V. Nazarova, A. Pavinski Bitar, K.J. Maurer, and H. Marquis. 2014. Misregulation of the broad-range phospholipase C activity increases the susceptibility of Listeria monocytogenes to intracellular killing by neutrophils. Microb. Infect. 16:104-113.
Abi Abdallah, D.S., A. Pavinski Bitar, F. Oliveira, S. Kamhawi, C. Meneses, J.J. Park, S. Mendez, J. Valenzuela, and H. Marquis. 2014. A Listeria monocytogenes-based vaccine that secretes sand fly salivary protein LJM11 confers long-term protection against vector-transmitted Leishmania major. Infect. Immun. 82:2736-2745.