Karel A. Schat
Dr. Schat is a Professor in the Department of Microbiology and Immunology.
He received the DVM degree from the State University, Utrecht, The Netherlands
in 1970, and his PhD from Cornell University in 1978 studying virology.
Since 1978, he has held successive positions at the College of Veterinary
Medicine, Cornell University. Throughout his career he has obtained continuous
extramural funding to study avian virology and especially Marek's disease
and recently chicken infectious anemia virus. Since 2006, he has been
studying the pathogenesis of infection with highly pathogenic avian influenza
H5N1 strains in a joint project between the Australian Animal Health Laboratory
(AAHL) of the CSIRO Livestock Industries, the CDC, and the College of
Veterinary Medicine. This research is conducted in the high containment
facilities of AAHL in Australia (details).
He received the Pfizer Award for Excellence in Poultry Research at the
136th Annual Convention of the AVMA in New Orleans, July, 1999, and the
Merck Award for Achievement in Poultry Science at the 98th Annual meeting
of the Poultry Science Association in Auburn, August, 2005.
Research Interests
| Graduate Fields | Lab
Members | Related Links | Selected
References
Research Interests
Virology, immunology, and molecular biology of Marek's disease virus,
chicken infectious anemia virus, and avian influenza. Pathogenesis of
Mycoplasma gallisepticum infection in house finches (Carpodacus mexicanus).
Avian virology and avian immunology in general. West Nile virus and evolution
of MHC in American crows.
Graduate Fields
Dr. Schat is a member of the following Graduate Fields:
Comparative Biomedical Sciences
Immunology
Lab Members
Priscilla O'Connell, Research Support Specialist
Keila Dhondt, Research Associate
Mike Piepenbrink, Postdoctoral Associate
Jessica Grodio, Graduate Student (DVM/PhD program)
Related Links
Selected References
Miller, M.M., K.W. Jarosinski, and K.A. Schat. (2005). Positive and negative
regulation of chicken anemia virus transcription. J
Virol, 79:2859-2868.
Jarosinski, K.W., N. Osterrieder, V.K. Nair, and K.A. Schat. (2005).
Attenuation of Marek's disease virus (MDV) by deletion of open reading
frame RLORF4 but not RLORF5a. J.
Virol. 79:11647-11659.
Jarosinski, K. W. and K.A. Schat. (2007). Multiple alternative splicing
to exons II and III of viral interleukin 8 (vIL-8) in the Marek's
disease virus genome: the importance of vIL-8 exon I. Virus
Genes. E-pub ahead of print (2006).
Li, X., K.W. Jarosinski, and K.A. Schat. (2006). Expression of Marek's
disease virus phosphorylated polypeptide pp38 produces splice variants
and enhances metabolic activity. Vet
Microbiol. 117:154-168.
Schat, K.A., and E. Baranowski. (2007). Animal vaccination and the evolution of viral pathogens. Rev. Sci. Tech. Off. Int. Epiz. 26:327-338.
Davison, F., Kaspers, B. and Schat, K.A. (eds). (2008). Avian Immunology, Elsevier, London, San Diego, CA. ISBN: 978-0-12-370634-3.
