Department of Molecular Medicine  

Department of Molecular Medicine Events

Research Work-in-Progress

Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research Moleculare Medicine Areas of Research


Fall 2014 / Winter 2015

4:00 pm Mondays, November - March
Lecture Hall III, Veterinary Research Tower


November 24

Qiyu Feng (Cerione Lab) - Microvesicle-carried VEGF90K stimulates tumor angiogenesis


December 1

Aparna Mahadevan (Kurpios Lab) - Pitx2 drives organ-specific asymmetric arterial and lymphatic development in the intestine
Stella Li (Cerione Lab) - Structure and function of glutaminase C: Towards a molecular understanding of a gateway enzyme in cancer cell metabolism

December 8

Aravind Sivakumar (Kurpios Lab) - Hyaluronan provides a mechanism for asymmetric organ morphogenesis
Kelly Sullivan (Cerione Lab) - The cancer stem cell marker aldehyde dehydrogenase 1A3 promotes the survival and migration of glioma stem cells by inducing tissue transglutaminase

December 15

Sachi Horibata (Coonrod Lab) - PAD2 as a therapeutic target for breast cancer
Joy Lin (Cerione Lab) - Interplay of small GTPases in heregulin-mediated signaling to mTOR/S6 kinase


January 5

Chengliang Zhang (Cerione Lab) - Halt tumor growth by combining anti-VEGF immunotherapy with inhibition of glutaminolysis
Kevin Michalski (Kawate Lab) - Gating and modulation of pannexin-1 channels

January 12

Bill Katt (Cerione Lab) - Development of small molecules that stabilize the “open” conformation of tissue transglutaminase
Kate Alexander (Garcia-Garcia Lab) - Novel mechanisms of imprinting control by TRIM28 during and after genome-wide reprogramming

January 19 - NO WIP, Martin Luther King Holiday

January 26

Dante Lepore (Collins Lab) - The functional significance of phosphorylated Sec4p
Akira Karasawa (Kawate Lab) - Crystallization and reconstitution of a P2X7 receptor


February 2 - NO WIP, BBS Recruitment

February 9

Frances Chen (Kurpios Lab) - CRISPR/Cas9 genome editing at the Pitx2 locus: functional annotation of regulatory elements at a genomic locus critical for left-right asymmetric organogenesis
Krista Giglio (Sondermann Lab) - Molecular mechanisms of a conserved c-di-GMP effector system that regulates biofilm formation via cell adhesion in Vibrio cholerae

February 16

Marcus Wilkes (Baird Lab) -The role of Cdc42 in regulating mast cell signaling
Ian Malgapo (Linder Lab) - Insights on the structure of DHHC

February 23

Colin Gottlieb (Linder Lab) - Dissecting the role of palmitate in structuring the catalytic domain of DHHC3
Ian Welsh (Kurios Lab) - Asymmetric 3D nuclear architecture accompanies novel complementary left-right gene expression from the critical Pitx2


March 2

Jocelyn Wang (Rudd Lab) - Homeostatic proliferation in neonatal mice alters the metabolic control of  CD8+ T cell activation
Ezen Choo (Dando Lab) - Hormonal modulation of the peripheral taste system

March 9

John O'Donnell (Sondermann Lab) - Characterizing differences in atlastin isoforms and resultant cellular phenotypes
Jordan Mohr (Baird Lab) - EGF receptors: stimulated and spontaneous oligomerization

March 16

Christopher Hosford (Chappie Lab) - Structural and functional characterization of the McrBC restriction complex

Kevin Siegenthaler (Sevier Lab) - tba

March 23

Joe Druso (Cerione Lab) - Cdc42 in the development and maintenance of the mammary gland

Gia Wang (Sevier Lab) - Oxidation of the HSP70 BiP protect cells against ER oxidative stress

March 30 - NO WIP, Spring Break



April 6

Rick Cooley (Sondermann Lab) - Controlling the biofilm: structural and physiologic insight into the conserved LapD/LapG signaling system