Y. Zheng, D. Zangrilli, R.A. Cerione, and A. Eva. The pleckstrin homology domain mediates transformation by oncogenic Dbl through specific intracellular targeting. Submitted to Nature.

U.S. Singh, J.W. Erickson, and R.A. Cerione. Identification and biochemical characterization of an 80 kDa GTP-binding/transglutaminase from rabbit liver nuclei. Biochemistry in press.

S. Bagrodia, B. Dˇrijard, R.J. Davis, and R.A. Cerione. Cdc42 and PAK-mediated signaling leads to JNK and p38 Map Kinase Activation. J. Biol. Chem. in press.

S. Bagrodia, S.J. Taylor, C.L. Creasy, J. Chernoff, and R.A. Cerione. Identification of a mouse p21Cdc42/Rac activated kinase (PAK). J. Biol. Chem. in press.

D.C. Gamett, T. Greene, A.R. Wagreich, H.H. Kim, J.G. Koland, and R.A. Cerione. Heregulin-stimulated signaling in rat pheochromocytoma cells: Evidence for erbB3 interactions with neu/erbB2 and p85. J. Biol. Chem. 270, 19022-19027 (1995).

J.W. Erickson, R. Mittal, and R.A. Cerione. Use of resonance energy transfer to determine the proximity of the guanine nucleotide binding site of transducin relative to a conformationally-sensitive site on the gamma subunit of the cyclic GMP phosphodiesterase. Biochemistry 34: 8693-8700 (1995).

Y. Zheng, M.F. Olson, A. Hall, R.A. Cerione, and D. Toksoz. Direct involvement of the small GTP-binding protein Rho in lbc oncogene function. J. Biol. Chem. 270(16): 9031-9034 (1995).

P. Cicchetti, A.J. Ridley, Y. Zheng, R.A. Cerione, and D. Baltimore. cDNA cloning and characterization of 3BP-1, an SH3 domain binding protein which has GAP activity for Rac and Inhibits growth factor induced membrane ruffling in fibroblasts. EMBO Journal 14, 3127-3125 (1995).

J.V. Platko, D.A. Leonard, C.N. Adra, R.J. Shaw, R.A. Cerione and B. Lim. A single residue can modify target-binding affinity and activity of the functional domain of the Rho-subfamily GDP Dissociation Inhibitors. PNAS 92: 2974-2978 (1995).

Y. Zheng, A. Bender and R.A. Cerione. Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae. J. Biol. Chem. 270, 626-630 (1995).

Leonard, D.A., Evans, T., Hart, M., Cerione, R.A., and Manor, D. Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy. Biochemistry 33: 12323-12328 (1994).

M.J. Sutcliffe, J. Feltham, R.A. Cerione, and R.E. Oswald. Model building predicts an additional conformational switch when GTP binds to the Cdc42Hs protein. Protein and peptide letters 1, 84-91 (1994).

J. Peterson, Y. Zheng, L. Bender, A. Meyers, R.A. Cerione, and A. Bender. Interactions between the bud-emergence proteins Bem1p and Bem2p and rho-type GTPases in yeast. J. Cell Biol. 127: 1395-1406 (1994).

R. Mittal, R.A. Cerione, and J.W. Erickson. Aluminum fluoride activation of bovine transducin induces two distinct conformational changes in the a subunit. Biochemistry 33: 10178-10184 (1994).

D.C. Gamett and R.A. Cerione. Oncogenically activated or ligand-stimulated neu kinase stimulates neurite outgrowth in PC12 cells. FEBS Letts. 351: 335-339 (1994).

P.M. Guy, J.V. Platko, L.C. Cantley, R.A. Cerione and K.L. Carraway. Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity. Proc. Natl. Acad. of Sci. U.S.A. 91: 8132-8136 (1994).

Y. Zheng, S. Bagrodia, and R.A. Cerione. Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85. J. Biol. Chem. 269: 18727-18730 (1994).

M.X. Slikowski, G. Schaefer, R.W. Akita, J.A. Lofgren, V.D. Fitzpatrick, A. Nuijens, B.M. Fendley, R.A. Cerione, R.L. Vandlen and K.L. Carraway. Coexpression of erbB2 and erbB3 proteins reconstitutes a high affinity receptor for heregulin. J. Biol. Chem. 269: 14661-14665 (1994).

K.L. Carraway, M.X. Sliwkowski, R.W. Akita, J.V. Platko, P.M. Guy, A. Nuijens, A.J. Diamonti, R.L. Vandlen, L.C. Cantley and R.A. Cerione. The erbB3 gene product is a receptor for heregulin. J. Biol. Chem. 269: 14303-14306 (1994).

W.J. Phillips and R.A. Cerione. A carboxyl terminal peptide of bovine rhodopsin binds to the transducin-a subunit and facilitates its activation. Biochem. J. 299: 351-357 (1994).

Y. Zheng, R.A. Cerione, and A. Bender. Regulators of the yeast bud-site-assembly GTPase Cdc42. J. Biol. Chem. 269: 2369-2372 (1994).

M.J. Hart, A. Eva, D. Zangrilli, S.A. Aaronson, T. Evans, R.A. Cerione, and Y. Zheng. Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the DBL oncogene product. J. Biol. Chem. 269: 62-65 (1994).

E.T. Barfod, Y. Zheng, W.J. Kuang, M.J. Hart, T. Evans, R.A. Cerione and A. Ashkenozi. Cloning and expression of a human CDC42 GTPase activating protein reveals a functional SH3-binding domain. J. Biol. Chem. 268: 26059-26062 (1993).

K.L. Carraway III and R.A. Cerione. Fluorescent-labeled growth factor molecules serve as probes for receptor binding and endocytosis. Biochemistry 32: 12039-12045 (1993).

C.N. Adra, J. Ko, D.A. Leonard, R.A. Cerione, and B. Lim. Identification of a novel GDP-dissociation inhibitor preferentially expressed in hematopoietic cells. Genes, Chromosomes and Cancer 8: 253-261 (1993).

Y. Zheng, M.J. Hart, K. Shinjo, T. Evans, A. Bender, and R.A. Cerione. Biochemical Comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. J. Biol. Chem. 268: 24629-24634 (1993).

K.L. Carraway III and R.A. Cerione. Inhibition of epidermal growth factor receptor aggregation by an antibody directed against the epidermal growth factor receptor extracellular domain. J. Biol. Chem. 268: 23860-23867 (1993).

J.W. Erickson and R.A. Cerione. Regulation of the cGMP phosphodiesterase in bovine rod outer segments: Use of resonance energy transfer to distinguish between associative and dissociative activation mechanisms. J. Biol. Chem. 268(5): 3328-3333 (1993).

M.J. Hart, Y. Maru, D. Leonard, O.N. Witte, T. Evans, and R.A. Cerione. A GDP-Dissociation inhibitor also serves as a GTPase-inhibitor for the ras-like protein CDC42Hs. Science 258: 812-815 (1992).

D. Leonard, M.J. Hart, A. Eva, W. Henzel, T. Evans, and R.A. Cerione. The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein. J. Biol. Chem. 267: 22860-22868 (1992).

W.J. Phillips, S.C. Wong, and R.A. Cerione. Rhodopsin/transducin interactions: 2) Influence of the transducin-bg subunit complex on the coupling of the transducin-a subunit to rhodopsin. J. Biol. Chem. 267: 17040-17046 (1992).

W.J. Phillips and R.A. Cerione. Rhodopsin/transducin interactions: 1) Characterization of the binding of the transducin-bg subunit complex to rhodopsin using fluorescence spectroscopy. J. Biol. Chem. 267: 17032-17039 (1992).

P.M. Guy, K.L. Carraway, and R.A. Cerione. Biochemical comparisons of the normal and oncogenic forms of insect cell-expressed neu tyrosine kinases. J. Biol. Chem. 267: 13851-13856 (1992).

V. Narasimhan, O. Hamill, and R.A. Cerione. The effects of the neu tyrosine kinase, and the corresponding forms of an immunoglobulin E receptor/neu tyrosine kinase fusion protein, on Xenopus oocyte maturation. FEBS Letts. 303: 164-168 (1992).

M.J. Hart, A. Eva, T. Evans, S.A. Aaronson, and R.A. Cerione. The dbl oncogene product catalyzes guanine nucleotide exchange on the CDC42Hs protein. Nature 354: 311-314 (1991).

M.J. Hart, K. Shinjo, A. Hall, T. Evans, and R.A. Cerione. Identification of the human platelet GTPase activating protein (Gap) for the CDC42Hs protein. J. Biol. Chem. 266: 20840-20848 (1991).

W.J. Phillips and R.A. Cerione. Labeling of the beta subunit of transducin with an environmentally-sensitive fluorescent cysteine reagent: A spectroscopic probe for transducin subunit interactions. J. Biol. Chem., 266: 11017-11024 (1991).

J. Erickson, and R.A. Cerione. Resonance energy transfer as a direct monitor of GTP-binding protein-effector interactions: Activated a-transducin binding to the cGMP phosphodiesterase in the bovine phototransduction cascade. Biochemistry 30: 7112-7118 (1991).

K.L. Carraway, and R.A. Cerione. Comparisons of epidermal growth factor (EGF) receptor-receptor interactions in intact A431 cells and isolated plasma membranes: Large scale EGF receptor micro-aggregation is not detected during EGF-stimulated early events. J. Biol. Chem., 266: 8899-8906 (1991).

K. Shinjo, J.G. Koland, M.J. Hart, V. Narasimhan, D. Johnson, T. Evans, and R.A. Cerione. Molecular cloning of the human placental GTP-binding protein, Gp (G25K): Identification of this GTP-binding protein as the human homolog of the yeast cell cycle-division protein, CDC42. Proc. Natl. Acad. Sci. USA, 87: 9853-9857 (1990).

K.L. Carraway, J.G. Koland, and R.A. Cerione. Location of the epidermal growth factor binding site on the EGF receptor: A resonance energy transfer study. Biochemistry, 29: 8741-8747 (1990).

P.M. Guy, J.G. Koland and R.A. Cerione. The rhodopsin-stimulated activation-deactivation cycle of transducin: Kinetics of the intrinsic tryptophan fluorescence of the alpha subunit. Biochemistry, 29: 6954-6964 (1990).

M. Hart, P. Polakis, T. Evans and R.A. Cerione. Identification and characterization of a low molecular weight GTP binding protein which is a phospho-substrate for the epidermal growth factor receptor/tyrosine kinase. J. Biol. Chem., 265: 5990-6001 (1990).

J.G. Koland, K. O'Brien, and R.A. Cerione. Expression of epidermal growth factor receptor sequences as E. coli. fusion proteins: Applications in the study of tyrosine kinase function. Biochem. Biophys. Res. Commun., 166: 90-100 (1990).

J.G. Koland and R.A. Cerione. Activation of the EGF receptor kinase by divalent metal ions: Comparison of holoreceptor and isolated kinase domain properties. Biochimica Biophysica Acta, 1052: 489-498 (1990).

K.L. Carraway, III, J.G. Koland and R.A. Cerione. Visualization of EGF receptor aggregation in plasma membranes by fluorescence resonance energy transfer: Correlation of receptor activation with aggregation. J. Biol. Chem., 264: 8699-8707 (1989).

S. Kroll, W.J. Phillips and R.A. Cerione. The regulation of the cyclic GMP phosphodiesterase by the GDP-bound form of the alpha subunit of transducin. J. Biol. Chem., 264: 4490-4497 (1989).

W.J. Phillips, S. Trukawinski, and R.A. Cerione. An antibody-induced enhancement of the transducin-stimulated cyclic GMP phosphodiesterase activity. J. Biol. Chem., 264: 16679-16688 (1989).

R.A. Cerione, S. Kroll, R. Rajaram, C. Unson, P. Goldsmith and A. Spiegel. An antibody against the carboxy-terminal decapeptide of the alpha subunit of the retinal GTP binding proteins, transducin: Effects on transducin function. J. Biol. Chem. 263: 9345-9352 (1988).

W.J. Phillips and R.A. Cerione. The Intrinsic Fluorescence of the Alpha Subunit of Transducin: Measurement of Receptor-dependent Guanine Nucleotide Exchange. J. Biol. Chem. 263: 15498-15505 (1988).

W.A. Horne, M. Abdel-Ghany, E. Racker, G.A. Weiland, R.E. Oswald and R.A. Cerione. Functional reconstitution of skeletal muscle calcium channels: Separation of regulatory and channel components. PNAS 85: 3718-3722, (1988).

J.G. Koland and R.A. Cerione. Growth factor control of EGF receptor kinase activity via an intramolecular mechanism. J. Biol. Chem. 263(5): 2230-2237 (1988).

J. Krupinski, R. Rajaram, M. Lakonishok, J. Benovic and R.A. Cerione. Insulin-dependent phosphorylation of GTP binding proteins in phospholipid vesicles. J. Biol. Chem., 263: 12333-12341 (1988).

R.A. Cerione, P. Gierschik, C. Staniszewski, J.L. Benovic, J. Codina, R. Somers, L. Birnbaumer, A.M. Spiegel, R.J. Lefkowitz and M.G. Caron. Functional differences in the bg complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry 26: 1485-1491 (1987).

W.A. Horne, G.A. Weiland, R.E. Oswald, and R.A. Cerione. Rapid incorporation of the solubilized dihydropyridine receptor into phospholipid vesicles. Biochem. Biophys. Acta, 863: 205-212 (1986).

R.A. Cerione, C. Staniszewski, P. Gierschik, J. Codina, R.L. Somers, L. Birnbaumer, A.M. Spiegel, M.G. Caron, and R.J. Lefkowitz. Mechanism of guanine nucleotide regulatory protein mediated inhibition of adenylate cyclase: Studies with isolated subunits of transducin in a reconstituted system. J. Biol. Chem., 261: 9514-9520 (1986).

R.A. Cerione, J.W. Regan, H. Nakata, J. Codina, J.L. Benovic, P. Gierschik, R.L. Somers, A.M. Spiegel, L. Birnbaumer, R.J. Lefkowitz, and M.G. Caron. Functional reconstitution of the a2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles. J. Biol. Chem. 261: 3901-3909 (1986).

R.A. Cerione, C. Staniszewski, M.G. Caron, R.J. Lefkowitz, J. Codina, and L. Birnbaumer. A role for Ni in the hormonal stimulation of adenylate cyclase. Nature, 318: 293-295 (1985).

R.A. Cerione, J. Codina, B.F. Kilpatrick, C. Staniszewski, P. Gierschik, R.L. Somers, A.M. Spiegel, L. Birnbaumer, M.G. Caron and R.J. Lefkowitz. Transducin and the inhibitory nucleotide regulatory protein (Ni) inhibit the Ns (stimulatory nucleotide regulatory protein)-mediated stimulation of adenylate cyclase in phospholipid vesicle systems. Biochemistry 24: 4499-4503 (1985).

J.L. Benovic, L.J. Pike, R.A. Cerione, C. Staniszewski, T. Yoshimasa, J. Codina, L. Birnbaumer, M.G. Caron, and R.J. Lefkowitz. Phosphorylation of the mammalian b-adrenergic receptor by cyclic AMP-dependent protein kinase: Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein. J. Biol. Chem. 260: 7094-7101 (1985).

R.J. Lefkowtiz, R.A. Cerione, J. Codina, L. Birnbaumer, and M.G. Caron. Reconstitution of the b-adrenergic receptor. J. Membrane Biol. 87: 1-12 (1985).

R.A. Cerione, C. Staniszewski, J.L. Benovic, R.J. Lefkowitz, M.G. Caron, P. Gierschik, R. Somers, A.M. Spiegel, J. Codina, and L. Birnbaumer. Specificity of the functional interactions of the b-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. J. Biol. Chem. 260: 1493-1500 (1985).

M.G. Caron, R.A. Cerione, J.L. Benovic, B. Strulovici, C. Staniszewski, R.J. Lefkowitz, J. Codina-Salada, and L. Birnbaumer. Biochemical characterization of the adrenergic receptors: Affinity labeling, purification and reconstitution studies. Adv. Cyclic Nucleotide Res., 19: 1-12 (1984).

R.J. Lefkowitz, J.M. Stadel, R.A. Cerione, B. Strulovici, and M.G. Caron. Structure and function of b-adrenergic receptors: Regulation at the molecular level. Adv. Cyclic Nucleotide Res. 17: 19-28 (1984).

B. Strulovici, R.A. Cerione, B.F. Kilpatrick, M.G. Caron, and R.J. Lefkowitz. Direct demonstration of impaired functionality of purified desensitized b-adrenergic receptor in a reconstituted system. Science 225: 837-840 (1984).

R.A. Cerione, D.R. Sibley, J. Codina, J.L. Benovic, J. Winslow, E.J. Neer, L. Birnbaumer, M.G. Caron, and R.J. Lefkowitz. Reconstitution of a hormone-sensitive adenylate cyclase system: The pure b-adrenergic receptor and guanine nucleotide regulatory protein confer hormone responsiveness on the resolved catalytic unit. J. Biol. Chem. 259: 9979-9982 (1984).

R.A. Cerione, J. Codina-Salada, J.L. Benovic, R.J. Lefkowitz, L. Birnbaumer, and M.G. Caron. The mammalian b-adrenergic receptor: Reconstitution of functional interactions between the pure receptor and the pure stimulatory nucleotide binding protein (Ns) of the adenylate cyclase system. Biochemistry 23: 4519-4525 (1984).

R.A. Cerione, B. Strulovici, J.L. Benovic, R.J. Lefkowitz, and M.G. Caron. The pure b-adrenergic receptor: The single polypeptide confers catecholamine responsiveness to adenylate cyclase. Nature 306: 562-566 (1983).

R.A. Cerione, B. Strulovici, J.L. Benovic, C.D. Strader, M.G. Caron, and R.J. Lefkowitz. Reconstitution of b-adrenergic receptors in lipid vesicles: Affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system. Proc. Natl. Acad. Sci. USA 80: 4899-4903 (1983).

R.A. Cerione and T. Chase, Jr. The interactions of Rose Bengal and other aromatic anionic dyes with Mannitol-1-phosphate dehydrogenase from Escherichia coli. J. Protein Chem. 2: 383-397 (1983).

R.A. Cerione and T. Chase, Jr. Fluorescence investigations of coenzyme and substrate interactions in Mannitol-1-phosphate dehydrogenase of Escherichia coli. J. Protein Chem. 2: 371-381 (1983).

R.A. Cerione, R.E. McCarty, and G.G Hammes. Spatial relationships between specific sites on reconstituted chloroplast H+-adenosinetriphosphatase and the phospholipid vesicle surface. Biochemistry 22: 769-776 (1983).

R.A. Cerione and G.G. Hammes. Structural mapping of nucleotide binding sites on chloroplast coupling factor. Biochemistry 21: 745-752 (1982).

R.A. Cerione and G.G. Hammes. Nucleotide interactions with the dicyclohexylcarbodiimide-sensitive adenosinetriphosphatase from spinach chloroplasts. Biochemistry 20: 3359-3365 (1981).

Reviews/Book Chapters

Y. Zheng, M.J. Hart, and R.A. Cerione. Guanine nucleotide exchange catalyzed by the dbl oncogene product. Methods in Enzymology, eds. W.E. Balch, C.J. Der, A. Hall) in press.

D. Leonard and R.A. Cerione. Solubilization of Cdc42Hs from membranes by rho-GDI. Methods in Enzymology, eds. W.E. Balch, C.J. Der, A. Hall) in press.

R.A. Cerione, M.J. Hart, D. Leonard. Purification of baculovirus-expressed Cdc42Hs. In: Small GTPases and their regulators (Methods in Enzymology, eds. W.E. Balch, C.J. Der, A. Hall) in press.

R.A. Cerione. Dbl. In: Guidebook to the small GTPases (Oxford University Press, ed. L.A. Huber, M. Zerial, J. Tooze) in press.

R.A. Cerione. Cdc42Hs. In: Guidebook to the small GTPases (Oxford University Press, ed. L.A. Huber, M. Zerial, J. Tooze) in press.

R.A. Cerione. Fluorescence assays for G protein interactions. In: G proteins and Signal Transduction (Methods in Enzymology, ed. R. Iyengar) Vol. 237, 409-423 (1994).

M.J. Hart, D. Leonard, K. Shinjo, T. Evans, and R.A. Cerione. The Gp/G25K Protein: The mammalian homolog for the yeast cell-division-cycle protein, CDC42. In: GTP-binding Proteins: The ras superfamily (CRS Press, Inc., eds. J.C. Lacal and Frank McCormick) in press.

M.J. Hart, D. Leonard, Y. Zheng, K. Shinjo, T. Evans, and R.A. Cerione. The mammalian homolog of the yeast cell-division-cycle protein, CDC42Hs: Evidence for the involvement of a rho-subtype GTP-binding protein in cell growth regulation. In "Handbook of Experimental Pharmacology: GTPases in Biology" I and II (Springer-Verlag, Berlin; eds. B. Dickey and Lutz Birnbaumer) Vol. 108, 580-595 (1993).

R.A. Cerione. Reconstitution of receptor-GTP-binding protein interactions. Biochimica et Biophysica Acta "Reviews on Biomembranes", 1071: 473-501 (1991).

T. Evans, M. Hart, and R.A. Cerione. The ras-superfamilies: regulatory proteins and posttranslational modifications. In: Current Opinion in Cell Biology, 3: 185-191 (1991).

W.J. Phillips and R.A. Cerione. Fluorescence investigations of receptor-mediated processes. In: Fluorescence in Biochemistry and Cell Biology (Plenum Publishing Corporation. New York, New York ed. T.G. Dewey) 135-167 (1991).

R.A. Cerione and E.M. Ross. Reconstitution and quantitation of regulated adenylate cyclase activity. In: Adenylate and Guanylate Cyclases (Methods in Enzymology, eds. R.A. Johnson and J.D. Corbin) Vol. 195, 329-342 (1991).

R.A. Cerione. Reconstitution of receptor/G protein-coupled signal transduction. In: Receptors: A Practical Approach (IRL Press, Oxford, England, ed. Dr. E.C. Hulme), 59-82 (1990).

R.A. Cerione. Mechanisms of receptor-coupled signal transduction. Proceedings of the Wenner-Gren Symposium, (ed. K. Fuxe, L.F. Agnati) 48: 200-211 (1987).

M.G. Caron, J.L. Benovic, L.M.F. Leeb-Lundberg, R.A. Cerione, J.W. Regan, J.W. Lomasney, S. Cotecchia, H. Nakata, D.R. Sibley, R.H. Strasser, and R.J. Lefkowitz. Biochemical characterization of the adrenergic receptors: Regulation of responsiveness by phosphorylation of the receptors. In: The Ninth International Symposium on Brain Sciences Proceedings (1986).

R.A. Cerione, J.L. Benovic, J. Codina, . Birnbaumer, R.J. Lefkowitz, and M.G. Caron. The b-adrenergic receptor-coupled adenylate cyclase: Reconstitution of the functional interactions of the various purified components. In: The Receptors (P.M. Conn, ed.), Academic Press, Orlando, Florida, Vol. 4, 2-34 (1986).

R.H. Strasser, R.A. Cerione, J. Codina, L. Birnbaumer, R.J. Lefkowitz, and M.G. Caron. The b-adrenergic receptor-coupled adenylate cyclase: Reconstitution of the functional interactions of the various purified components. In: The Receptors (P.M. Conn, ed.), Academic Press, Orlando, Florida, Vol. 9, (1986).

M.G. Caron, J.L. Benovic, G.L. Stiles, L.M.F. Leeb-Lundberg, K.E.J. Dickinson, J.W. Regan, S.L. Heald, P. Nambi, B. Strulovici, R.A. Cerione, and R.J. Lefkowitz. Biochemical properties of the adrenergic receptors delineated by purification and photoaffinity labeling. Symposia Medica Hoechst 19, Adrenergic Receptors: Molecular Properties and Therapeutic Implications (R.J. Lefkowitz and E. Lindenlaub, eds.), Schattaueur Verlag, Stuttgart, West Germany, 7-27 (1985).

R.A. Cerione, J.L. Benovic, J.Codina, C. Staniszewski, D.R. Sibley, J. Winslow, P. Gierschik, R. Somers, B. Strulovici, A.M. Spiegel, E.J. Neer, L. Birnbaumer, R.J. Lefkowitz, and M.G. Caron. Reconstitution of the b-adrenergic-coupled adenylate cyclase system into phospholipid vesicles. Symposia Medica Hoechst 19, Adrenergic Receptors Molecular Properties and Therapeutic Implications (R.J. Lefkowitz and E. Lindenlaub, eds.), Schattaueur Verlag, Stuttgart, West Germany, 299-326 (1985).

L. Birnbaumer, J. Codina, T. Sunyer, W. Rosenthal, J.D. Hildebrandt, R.A. Cerione, M.G. Caron, R.J. Lefkowitz, and R.D. Sekura. Structural and functional properties of Ns and Ni, the regulatory components of adenylyl cyclases. In: Pertusis Toxin, (R.D. Sekura, J. Moss, and M. Vouplisa, eds.), Academic Press, New York, 77-104 (1985).

L. Birnbaumer, J. Codina, T. Sunyer, J.D. Hildebrandt, R.A. Cerione, R.J. Lefkowitz, and M.G. Caron. Dual coupling mechanisms in the regulation of cAMP formation. In: "The Role of Receptors in Biology and Medicine", (ed. A.M. Gotto, Jr., and B.W. O'Malley) Raven Press, New York (1986) pp. 193-211.

M.G. Caron, R.A. Cerione, L.M.F. Leeb-Lundberg, J.L. Benovic, J.W. Regan, K.E.J. Dickinson, S.L. Heald, and R.J. Lefkowitz. Biochemical characterization of the adrenergic receptors: Purification, affinity labeling and reconstitution studies. Proceedings of the 7th International Congress of Endocrinology (1985).

L. Birnbaumer, J. Codina, R. Mattera, R.A. Cerione, J.D. Hildebrandt, T. Sunyer, F.J. Rojas, M.G. Caron, R.J. Lefkowitz, and R. Iyengar. Regulation of hormone receptors and adenylyl cyclase by guanine nucleotide binding N protein. In: Recent Progress in Hormone Research (R.O. Greep, ed.), Academic Press, Orlando, Florida, Vol. 41, pp. 41-99 (1985).

L. Birnbaumer, J. Codina, R. Mattera, J.D. Hildebrandt, T. Sunyer, F.J. Rojas, R.A. Cerione, M.G. Caron, and R.J. Lefkowitz. The structural basis for the reciprocal regulation of hormone receptors and adenylyl cyclases with special emphasis on the mode of action of glucagon. In: Hormonal Regulation of Gluconeogenesis, ed. by Naomi Kraus-Friedmann, C.R.C. Press in Boca Raton, FL. Vol. 2 (1986).

R.J. Lefkowitz, R.A. Cerione, J.L. Benovic, B. Strulovici, G.L. Stiles, J. Codina, L. Birnbaumer, and M.G. Caron. Purification, characterization and reconstitution of the adenylate cyclase-coupled b-adrenergic receptor. In: IUPHAR 9th International Congress of Pharmacology, Proceedings (W. Paton, J. Mitchell and P. Turner, eds.), The Macmillan Press Ltd., Lond, England, Vol. 1, pp. 293-297 (1984).

R.J. Lefkowitz, P. Nambi, J.M. Stadel, R.A. Cerione, B. Strulovici, and M.G. Caron. Beta-adrenergic receptors: Physiological regulation studied at the molecular level. Proceedings of the International Symposium on Catecholamines as Hormone Regulators, 18: 65-75 (1985) Raven Press, New York).