My research interests have evolved from studies of basic metabolism in ruminants and genetics to veterinary epidemiology, economic modeling and food safety.  The two main areas of investigations currently ongoing in my laboratory are: 1) mathematical modeling of zoonotic infectious diseases, and 2) optimizing health and management decisions.  Both of these areas of research offer opportunities for training in epidemiological and mathematical modeling, genetic analysis and economic methods.

1973 B.V.M., College of Vet. Med., Helsinki, Finland
1977 L.V.M.,(equiv DVM) College of Vet. Med., Helsinki, Finland
1980 Food Hygienist, College of Vet Med, Helsinki, Finland
1982 M.P.V.M., in Epidemiology, University of California, Davis
1983 M.S., in Genetics, University of California, Davis
1985 D.V.M.  (equiv Ph.D.), in Vet. Med., College of Vet. Med., Helsinki
2002 Diplomate ECVPH (European College of Vet. Public Health)

American Dairy Science Association
American Veterinary Medical Association
Association of Teachers of Veterinary Public Health and Preventive Medicine
Finnish Veterinary Medical Association
New York State Veterinary Medical Society
Nordic Association of Veterinary Epidemiology

Perspective

Lanzas, C., Ayscue, P., Ivanek, R., Gröhn, Y.T.: Model or meal? Animal agriculture systems as models for infectious diseases of humans. Nature Reviews, Microbiology. 2010, 8: 139-148.

Dubberke, E.R., Haslam, D.B., Lanzas, C., Bobo, L.D., Burnham, C.-A., D., Gröhn, Y.T., Tarr, P.I.: The ecology and pathobiology of Clostridium difficile infections: An interdisciplinary challenge. Zoonosis and Public Health, 2011, 58: 4-20.

Mathematical Modeling

Ayscue, P., Lanzas, C., Ivanek, R., and Gröhn Y.T.: Modeling Escherichia coli O157:H7 Population Dynamics in Feedlots. Foodborne Pathogens and Disease. 2009. 6: 461-470.

Lu, Z., Gröhn, Y.T., Smith, R.L., Wolfgang, D.R., Van Kessel, J.S., and Schukken, Y.H: Assessing the potential impact of Salmonella vaccine in an endemically infected dairy herd. J. of Theoretical Biology. 2009, 259: 770-784.

Ivanek, R.., Gröhn, Y.T., Wells, M.T., Lembo Jr, A.J., Sauders, B.D. and Wiedmann,M.:. Modeling of spatially referenced environmental and meteorological factors influencing the probability of Listeria spp. isolation from natural environments. Applied & Environmental Microbiology. 2009, 75: 5893-5909.

Lanzas, C. Warnick, L.D. James, K.L., Wiedmann, M., Gröhn, Y.T.: Transmission dynamics of a multi-drug resistant Salmonella Typhimurium outbreak in a dairy farm. Foodborne Pathogens and Disease. 2010, 7: 467-474.

Lu, Z., Schukken, Y.H, Smith, R.L., Wolfgang, D.R., Van Kessel, J.S., and Gröhn, Y.T.: Stochastic simulations of a multi-group compartmental model for Johne’s disease on US dairy herds with test-based culling interventions. Journal of Theoretical Biology. 2010 21; 264(4):1190-201.

Pradhan, A.K., Ivanek, R., Gröhn, Y.T., Bukowski, R., Geornaras, I., Sofos, J.N., Wiedmann, M.: Quantitative risk assessment of listeriosis-associated deaths due to Listeria monocytogenes contamination of deli meats originating from manufacture and retail. Journal of Food Protection, 2010, 73: 620-630.

Lanzas, C., Warnick, L.D., James, K.L., Wright, E.M., Wiedmann, M., Gröhn, Y.T.: Transmission dynamics of a multidrug-resistant Salmonella Typhimurium outbreak in a dairy farm. Foodborne Pathogens and Disease, 2010, 7: 467-474.

Lanzas, C., Lu, Z., Gröhn, Y.T.: Mathematical modeling of the transmission and control of foodborne pathogens and antimicrobial resistance at pre-harvest. Foodborne Pathogens and Disease, 2011, 8: 1-10.

Latorre, A.A., Pradhan, A.K., Van Kessel, J.A., Karns, J.S., Boor, K.J., Rice, D.H., Mangione, K.J., Gröhn, Y.T., Schukken, Y.H.: Quantitative risk assessment of listeriosis due to consumption of raw milk. Journal of Food Protection, 2011, 74: 1268-1281.

Lanzas, C., Dubberke, E.R., Lu, Z., Reske, K.A., Gröhn, Y.T.: Epidemiological model for Clostridium difficile transmission in healthcare settings. Infection Control and Hospital Epidemiology, 2011, 32: 553-561.

Teose, M., Ahmadizadeh, K., O’Mahony, E., Smith, R.L., Ju. Z., Ellner, S.P., Gomes, C., Gröhn, Y.T.: Embedding system dynamics in agent based models for complex adaptive systems. Int. Joint Conf. Artificial Intelligence. AAAI Press Proceedings, 7, 19-22, 2011.

Pradhan, A., Ivanek, R., Gröhn, Y.T., Bukowski, R., Wiedmann, M.: Comparison of public health impact of Listeria monocytogenes product-to-product and environmental-to-product contamination of deli meats at retail. Journal of Food Protection, 2011, 74: 1860-1868.

Volkova, V., Lanzas, C., Lu, Z., Gröhn Y.T.: Mathematical model of plasmid-mediated resistance to ceftiofur in commensal enteric Escherichia coli of cattle. PLoS ONE 2012, 7(5): e36738. doi:10.1371/journal.pone.0036738

Reksen, O., Gröhn Y.T., Barlow, J.W., and Schukken, Y.H.: Transmission dynamics of intramammary infections with coagulase-negative staphylococci. J. Dairy Sci., 2012, 95: 4899-4910.

Optimizing Health and Management

Smith, R.L., Gröhn, Y.T., Pradhan, A., Whitlock, R.H., Van Kessel, J.S., Schukken, Y.H.: A longitudinal study for the impact of Johne’s Disease on milk production in individual cows. J. Dairy Sci. 2009, 92: 2653-2661.

Schukken, Y.H, Hertl, J.A., Bar, D., Bennett, G.J., Gonzalez, R.N., Rauch, B., Santisteban, C. Schulte, H.F., Tauer., L.., Welcome F.L., Gröhn, Y. T..: Effects of repeated Gram-Positive and Gram-Negative Clinical Mastitis Episodes on Milk Yield loss in Holstein Dairy Cows. J. Dairy Sci. 2009, 92: 3091-3105.

Hertl, J.A., Gröhn, Y. T., Leach, J.D.G., Bar, D., Bennett, G.J., Gonzalez, R.N., Rauch, B.J., Welcome F.L., Tauer., L.W., and Schukken, Y.H: Effects of clinical mastitis due to Gram-positive and Gram-negative bacteria, and other organisms, on the probability of conception in New York State Holstein dairy cows. J. Dairy Sci. 2010, 93: 1551-1560.

Smith, R.L., Strawderman, R.L., Wells, S.J., Pradhan, A., Whitlock, R.H., Van Kessel, J.S., Schukken, Y.H., Gröhn, Y.T.: Effect of Johne’s disease status on reproduction and culling in dairy cattle. J. Dairy Sci., 2010, 93: 3513-3524.

Cha, E., Hertl, J.A., Bar, D., and Gröhn, Y.T.: The cost of different types of lameness in dairy cows calculated by dynamic programming. Prev Ved Med, 2010, 97: 1-8.

Schukken, Y.H., Bar, D., Hertl, J., Gröhn, Y.T.: Correlated time to event data: Modeling
repeated clinical mastitis data from dairy cattle in New York State. Preventive Veterinary
Medicine, 2010, 97: 150-156.

Dressler, J.B., Smith, R.L., Tauer, L.W., Schukken, Y.H., Gröhn, Y.T.: Economic analysis of the cross-reactivity of Johne’s disease vaccination with tuberculosis in dairy cattle. The American Journal of Agricultural Economics, 2010, 92: 1446-1455.

Wang, C., Turnbull, B.W., Nielsen, S.S., Gröhn, Y.T.: Bayesian analysis of longitudinal Johne’s disease diagnostic data without a gold standard test. Journal of Dairy Science, 2011, 94: 2320-2328.

Cha, E., Bar, D., Hertl, J.A., Tauer, L.W., Bennett, G., González, R.N., Schukken, Y.H., Welcome, F.L., Gröhn, Y.T.: The cost and management of different types of clinical mastitis in dairy cows estimated by dynamic programming. Journal of Dairy Science, 2011, 94: 4476-4487.

Hertl, J.A., Schukken, Y.H, Bar, D., Bennett, G.J., Gonzalez, R.N., Rauch, B.J., Welcome, F.L., Tauer, L.W., Gröhn, Y.T.: The effect of recurrent episodes of clinical mastitis caused by gram-positive and gram-negative bacteria and other organisms on mortality and culling in Holstein dairy cows. Journal of Dairy Science, 2011, 94: 4863-4877.

Smith, R.L., Schukken, Y.H., Pradhan, A.K., Smith, J.M., Whitlock, R.H., Van Kessel, J.S., Wolfgang, D.R., Gröhn, Y.T.: Environmental contamination with Mycobacterium avium subsp. paratuberculosis in endemically infected dairy herds. Preventive Veterinary Medicine 2011 Oct 1; 102(1): 1-9.

Cho, J., Tauer, L.W., Schukken, Y.H., Gomez, M.I., Smith, R.L., Zhao, L. and Gröhn, Y.T.: Economic analysis of Mycobacterium avium subsp. paratuberculosis vaccines in dairy herds. Journal of Dairy Science, 2012, 95: 1855-1872.