Population Medicine & Diagnostic Sciences


Cats  

Advancing the health and well-being of animals and people


Dogs  

Advancing the health and well-being of animals and people


Pig  

Advancing the health and well-being of animals and people


Cells  

Advancing the health and well-being of animals and people


Cattle  

Advancing the health and well-being of animals and people


Horses  

Advancing the health and well-being of animals and people


Daryl V. Nydam

Daryl Nydam

Associate Professor
Director, Quality Milk Production Services
Dept. of Population Medicine and Diagnostic Sciences
College of Veterinary Medicine
Cornell University
Ithaca, New York 14853
Phone:  607-253-4391
e-mail: dvn2@cornell.edu

Research Interests

My research interests are at the intersection of production animal agriculture and public health at the population level - with an emphasis on dairy cattle. On-going projects are in the areas of transition cow health and performance, calf infectious (especially zoonoses), and milk quality. I teach a variety of bovine herd health and epidemiology classes as well as provide consulting and clinical service for the dairy industry.


Education

  • B.S. - 1993 BioChemistry (Cum Laude) - University of New York at Geneseo
  • DVM - 1997 College of Veterinary Medicine, Cornell University
  • Ph.D. - 2002 Epidemiology - Comparative Biomedical Sciences Graduate School, Cornell University


Certifications and Licenses

  • Certificate of Tropical Ecology - Northeastern University, School for Field Studies Centre for Rainforest Studies, Yungaburra, Australia
  • Foreign Animal Disease Diagnostician Training Course, Plum Island Animal Disease Center
  • Dairy Health and Production Management, Ontario Veterinary College, University of Guelph

Research and Professional Experience

  • 1997- 1998 Associate Large Animal Veterinarian - Granville Veterinary Service, Granville, NY
  • 1997- 2004 Relief Veterinarian - C.W. Nydam Veterinary Clinic, P.C., Stamford, NY
  • 1998 - 2001 Veterinary Research Assistant - Section of Epidemiology, Dept. of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY
  • 2001 - 2006 Senior Extension Veterinarian - New York State Animal Health Diagnostic Center, Cornell University, Ithaca, NY
  • 2007 - 2012 Assistant Professor of Dairy Health and Production
  • 2013 – present Associate Professor of Dairy Health and Production; Dept. of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University
  • 2013 – present Director, Quality Milk Production Services; Animal Health Diagnostic Center


Graduate Faculty Field Memberships

  • Population Medicine, Ontario Veterinary College, University of Guelph
  • Animal Science, College of Agriculture and Life Sciences, Cornell University
  • Comparative Biomedical Sciences, Epidemiology, Immunology and Infectious Diseases, College of Veterinary Medicine, Cornell University


Selected Courses taught:

  • Summer Dairy Institute (http://www.vet.cornell.edu/summerdairyinstitute)
  • Feedlot Health Management Externship
  • Veterinarians and Food Animal Production Systems
  • Applied Dairy Nutrition for Practitioners
  • Dairy Herd Epidemiology
  • Herd Health and Biosecurity Risk Evaluation


Selected Publications
               
(from over 80)

  1. Nydam DV, Wade SE, Schaaf SL, Mohammed HO. Number of Cryptosporidium parvum oocysts and Giardia spp. cysts shed by dairy calves after natural infection. Am J Vet Res 2001; Oct; 62 (10):1612-1615
  2. Warnick LD, Nydam DV, Maciel A, Guard CL, Wade SE. Udder cleft dermatitis and Sarcoptic mange in a dairy herd. J Am Vet Med Assoc 2002; Jul 15; 221(2): 273-279
  3. Perkins G, Lamb S, Erb HN, Schanbacher B, Nydam DV, Divers TJ. Plasma adrenocorticotropin (ACTH) concentration and clinical response in horses treated for Cushing’s Disease with cyproheptadine and pergolide. Equine Vet J 2002; 34 (7) 679-685
  4. Nydam DV, Lindergard GL, Guard CL, Schaaf SL, Wade SE, Mohammed HO. Serological detection of exposure to Cryptosporidium parvum in cattle by ELISA and evaluation in relation to coprological tests. Parasitol Res. 2002; Sep; 88(9): 797-803
  5. Lindergard G, Nydam DV, Wade SE, Schaff SL, Mohammed HO. A novel multiplex polymerase chain reaction approach for detection of four human infective Cryptosporidium isolates: Cryptosporidium parvum, types H and C, Cryptosporidium canis, and Cryptosporidium felis in fecal and soil samples. J Vet Diag Invest 2003; 15: 262-267
  6. Perkins G, Nydam DV, Flaminio J., Ainsworth DM. Serum IgM concentrations in normal fit horses and in horses with lymphoma or other medical conditions. J Vet Intern Med. 2003; 17(3):337-342.
  7. Lindergard G, Nydam DV, Wade SE, Schaaf SL, Mohammed HO. The sensitivity of PCR detection of Cryptosporidium oocysts in fecal samples using two DNA extraction methods. Mol Diagn. 2003;7(3):147-53
  8. Gardner CE, Nydam DV, Ellis RG, Kelsey S, McDonough PL, Warnick LD. Management of an outbreak of salmonellosis on a commercial calf raising unit. Bov Pract 2004; Vol 38, No. 2: 147-154.
  9. Mitchell HM, Nydam DV, Reyher KK, Gilbert RO. The Opportunities Map at Cornell University: Finding Direction in Dairy Production Medicine. J Vet Med Educ. 2004; Winter;31(4):381-4
  10. Nydam DV, Lindergard GL, Santucci F, Schaff SL, Wade SE, Mohammed HO. Risk of Cryptosporidium parvum and Cryptosporidium hominis in dairy cattle in a New York watershed. Am J Vet Res 2005; 66 No. 3, 413-417.
  11. Stokol T and Nydam DV. Effect of anticoagulant, storage temperature, and duration of storage on non-esterified fatty acid and B-hydroxybutyrate concentrations from dairy cattle. J Dairy Sci 2005; 88 (9): 3139-44.
  12. Trotz-Williams LA, Martin SW, Martin D, Duffield T, Leslie KE, Nydam DV, Peregrine AS. Multiattribute evaluation of two simple tests for the detection of Cryptosporidium parvum oocysts in calf faeces. Vet Parasit 2005; 134: 15-23
  13. Nydam DV and Mohammed HO. Quantitative risk assessment of Cryptosporidium spp. infection in calves on dairy farms. J Dairy Sci 2005; 88(9): 3932-3943
  14. Trotz-Williams LA, Martin DS, Gatei W, Cama V, Peregrine AS, Martin SW, Nydam DV, Jamieson F, Xiao L. Genotype and subtype analyses of Cryptosporidium isolates from dairy calves and humans in southern Ontario. Parasit Res 2006 Sep;99(4):346-52
  15. Bicalho RC, Cheong SH, Warnick LD, Nydam DV, Guard CL. The effect of digit amputation or arthrodesis surgery on culling and milk production in Holstein dairy cows. J Dairy Sci 2006; Jul;89(7):2596-602
  16. Figueiredo MD, Nydam DV, Perkins GA, Mitchell HM, Divers TJ. Prognostic value of blood lactate concentration measured cow-side using a portable clinical analyzer in Holstein dairy cattle with abomasal disorders. J Vet Intern Med 2006; 20: 1463-1470
  17. Stokol T and Nydam DV. Effect of hemolysis on non-esterified fatty acid and B-hydroxybutyrate concentrations in bovine blood. J Vet Diagn Invest 2006; Sep; 18: 466-469
  18. Ziegler PA, Santucci F, Lindergard G, Nydam DV, Wade SE, Schaaf S, Chang YF, Mohammed HO. Evaluation of Polymerase chain reaction diagnosis of Cryptosporidium spp. in Dairy Cattle and Wildlife. Vet Ther. 2007 Summer;8(2):148-59
  19. Trotz-Williams LA, Martin SW, Leslie KE, Duffield T, Nydam DV, Peregrine AS. Calf-level risk factors for neonatal diarrhea and shedding of Cryptosporidium parvum in Ontario dairy calves: Prev Vet Med. June 2007; 82: 12-28
  20. Trotz-Williams LA, Martin SW, Leslie KE, Duffield T, Nydam DV, Peregrine AS. Association between management practices and within-herd prevalence of Cryptosporidium parvum shedding on dairy farms in southern Ontario. Prev Vet Med. Jan 2008; 83: 11-23
  21. Lanzas C, Warnick LD, Ivanek R, Ayscue P, Nydam DV, Gröhn YT. The risk and control of Salmonella outbreaks in calf-raising operations: a mathematical modeling approach. Vet Res. 2008; 39(6):61
  22. Nydam CW, Nydam DV, Guard CL, Gilbert RO. The Summer Dairy Institute model: Teaching dairy production medicine to entry-level veterinarians. J Vet Med Educ. 2009 Spring; 36(1):16-21
  23. Mohammed HO, Stipetic K, McDonough PL, Gonzalez RN, Nydam DV, Atwill ER. Identification of potential on-farm sources of Listeria monocytogenes in herds of dairy cattle. Am J Vet Res. 2009 Mar;70(3): 383-8
  24. Burton AJ, Nydam DV, Olivett TL, Divers TJ. Prognostic Indicators for Survival of downer cows managed with a flotation tank system in a referral hospital. J Am Vet Med Assoc. 2009 May 1;234(9):1177-82
  25. Linden TC, Nydam DV, Bicalho R C. Calf birth weight and its association with calf and cow survivability, disease incidence, reproductive performance, and milk production. J Dairy Sci. 2009 Jun;92(6):2580-8
  26. Ollivett TL, Nydam DV, Bowman DD, Zambriski JA, Bellosa ML, Linden TC, Divers TJ. Effect of nitazoxanide on cryptosporidiosis in experimentally infected neonatal dairy calves. J Dairy Sci. 2009; 92, 1643-1648
  27. Cummings KJ, Warnick LD, Cripps CJ, Gröhn YT, McDonough PL, Nydam DV, Alexander KA, Reed KE. The Incidence of Salmonellosis among Dairy Herds in the Northeastern United States. J Dairy Sci. 2009 Aug;92(8):3766-74
  28. Morkel P, Radcliffe RW, Jago M, DuPreez P, Flaminio MJBF, Nydam DV, Taft A, Lain D, Miller MM, Gleed RD. Acid-Base balance and ventilation during sterna and lateral recumbency in field immobilized black rhinoceros (Diceros bicornis bicornis) receiving oxygen insufflations. J Wildl Dis. 2010 Jan;46(1):236-45
  29. Ospina PA, Nydam DV, Stokol T, Overton TR. Evaluation of NEFA and β-hydroxybutyrate (BHB) in transition dairy cattle in the Northeast USA. Critical thresholds for prediction of clinical diseases. J Dairy Sci. 2010, 93: 546-554
    ++ Awarded most cited manuscript in the Journal of Dairy Science 2010-2013 by the American Dairy Science Association
  30. Burton AJ, Nydam DV, Long ED, Divers TJ. Clinical and pathological findings associated with bovine lymphosarcoma: A restrospective study of 112 cases. J Vet Intern Med. 2010, 24(4), 960-964
  31. Ospina PA, Nydam DV, Stokol T, Overton TR. Associations of elevated NEFA and β-hydroxybutyrate concentrations with early lactation reproductive performance and milk production in transition dairy cattle in the Northeast United States. J Dairy Sci. 2010, 93: 1596-1603
  32. Leone WM, Nydam DV, Welcome F, Warnick LD. Effects of removing cows from chronic oxytocin use during lactation. Bov Pract. 2010, 44(1) 83-87
  33. Ospina PA, Nydam DV, Stokol T, Overton TR. Association between the proportion of sampled transition cows with elevated NEFA and β-hydroxybutyrate (BHBA) and disease incidence, pregnancy rate, and milk production at the herd-level. J Dairy Sci. 2010, 93: 3595-3601
  34. Burton AJ, Nydam DV, Dearen TK, Mitchell K, Bowman DD and Xiao L. The prevalence of Cryptosporidium and identification of the Cryptosporidium horse genotype from foals in New York State. Vet Parasit. 2010 Nov 24;174(1-2):139-44
  35. Burton AJ, Nydam DV, Jones G, Zambriski JA, Linden TC, Cox G, Davis R, Brown A, Bowman DD. Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine. Vet Parasit. 2011 Jan 10;175(1-2):178-81
  36. Bellosa ML, Nydam DV, Liotta JL, Zambriski JA, Linden TC, Bowman DD. A Comparison of Fecal Percent Dry Matter and Number of Cryptosporidium parvum Oocysts Shed to Observational Fecal Consistency Scoring in Dairy Calves. J Parasitol. 2011 97(2): 349-351
  37. Cheong SH, Nydam DV, Crosier BM, Galvao KN, Gilbert RO. Cow and herd level risk factors for subclinical endometritis in lactating Holstein cows. J Dairy Sci. 2011, 94: 762-770
  38. Galvão KN, Pighetti GM, Cheong SH, Nydam DV, Gilbert RO. Association between interleukin-8 receptor (CXCR1) polymorphism and disease incidence, production, reproduction, and survival in Holstein cows. J Dairy Sci. 2011 94(4):2083-2091
  39. Soberon F, Ryan CM, Nydam DV, Galton DM, Overton TR. The Effects of Increased Milking Frequency during Early Lactation on Milk Yield and Milk Composition on Commercial Dairy Farms. J Dairy Sci. 2011, 94:4398-4405
  40. McArt JAA, Nydam DV, Ospina PA, Oetzel GR. A field trial on the effect of propylene glycol on milk yield and resolution of ketosis in fresh cows diagnosed with subclinical ketosis. J Dairy Sci. 2011, 94: 6011-6020
  41. Huzzey JM, Nydam DV, Grant RJ, Overton TR. Associations between prepartum cortisol, haptoglobin, and non-esterified fatty acids and postpartum health status. J Dairy Sci. 2011, 94: 5878-5889
  42. Cheong SH, Nydam DV, Galvao KN, Crosier BM, Ricci A, Caixeta L, Fraga M, Gilbert RO. Use of urinary reagent test strips for diagnosis of endometritis in dairy cows. Therio. 2012, 77(5):858-64
  43. Morkel P, Miller MM, Jago M, Radcliffe RW, duPrez P, Olea-Popelka F, Nydam DV, Taft A, Gleed RD. Serial Temperature Monitoring and Comparison of Rectal and Muscle Temperatures in Immobilized Free-Ranging Black Rhinoceros (Diceros bicornis). J Zoo Wild Med. 2012, 43(1): 120-124
  44. Burton AJ, Nydam DV, Mitchell K, Bowman DD. The prevalence of Cryptosporidium shedding in alpaca crias and their dams in the Northeastern USA. J Am Vet Med Assoc. 2012, 241(4):496-8
  45. Ollivett TL, Nydam DV, Linden TC, Bowman DD, Van Amburgh MA. Effect of nutritional plane on health and performance in dairy calves after experimental infection with Cryptosporidium parvum. J Am Vet Med Assoc. 2012, 241(11):1514-1520
    ++ Awarded in Top 10 papers of 2012 in food animal medicine by the American College of Veterinary Internal Medicine
  46. Cheong SH, Nydam DV, Galvao KN, Crosier BM, Gilbert RO. Effects of diagnostic low-volume uterine lavage shortly before first service on reproductive performance, culling, and milk production in dairy cows. Therio. 2012, 77(6): 1217-22
  47. Ospina PA, Nydam DV, DiCiccio TJ. The risk ratio, an alternative method to the odds ratio for estimating the association between multiple risk factors and a dichotomous outcome. J Dairy Sci. 2012, 95: 2576-2584
  48. McArt JAA, Nydam DV, Oetzel GR. A field trial on the effect of propylene glycol on displaced abomasum, removal from herd, and reproduction in fresh cows diagnosed with subclinical ketosis. J Dairy Sci. 2012, 95: 2505-2512
  49. McArt JAA, Nydam DV, Oetzel GR. Epidemiology of subclinical ketosis in early lactation dairy cattle. J Dairy Sci. 2012, 95: 5056-5066
  50. Huzzey JM, Nydam DV, Grant RJ, Overton TR. The effects of overstocking Holstein dairy cattle during the dry period on cortisol production and energy metabolism. J Dairy Sci. 2012, 95: 4421-4433
  51. Zambriski JA, Maves RC, Nydam DV, Ayvar V, Cepeda D, Castillo R, Diaz-Pino A, Saito M, Gilman RH. Effect of storage temperature and sample volume on Brucella melitensis isolation from goat milk. Intern J Trop Dis and Hygen. 2012, 2(3):207-213
  52. McArt JAA, Nydam DV, Oetzel GR. Dry period and parturient predictors of early lactation hyperketonemia in dairy cattle. J Dairy Sci. 2013, 96: 198-209
  53. Zambriski JA, Nydam DV, Bowman DD, Bellosa ML, Burton AJ, Linden TC, Liotta JL, Ollivett TL, Tondello-Martins L, Mohammed HO. Description of fecal shedding of Cryptosporidium parvum oocysts in experimentally challenged dairy calves. Parasit Res. 2013 Mar; 112(3) 1247-54
  54. Croushore WS, Ospina PA, Welch DC, Zawisza DJ, Nydam DV. The association between β-hydroxybutyrate concentration at diagnosis of left displaced abomasums in dairy cows and removal from the herd post-surgical correction. J Am Vet Med Assoc. 2013 243(9): 1329-33
  55. Zambriski JA, Nydam DV, Wilcox ZJ, Bowman DD, Mohammed HO, Liotta JL. Cryptosporidium parvum: Determination of ID50 and the dose-response relationship in experimentally challenged dairy calves. Vet Parasit. 2013, 197(1-2):104-12
  56. Teixeira AGV, Bicalho MLS, Machado VS, Oikonomou G, Kacar C, Foditsch C, Young R, Knauer WA, Nydam DV, Bicalho RC. Heat and ultraviolet light treatment of colostrum and hospital milk: Effects on colostrum and hospital milk characteristics and calf health and growth parameters. Vet J. 2013, Aug;197(2):175-81
  57. Ospina PA, McArt JA, Overton TR, Stokol T, Nydam DV. Using non-esterified fatty acids and β-hydroxybutyrate concentrations during the transition period for herd-level monitoring of increased risk of disease and decreased reproductive and milking performance. Vet Clin N Am. 2013, Vol 29; 387-412
  58. McArt JAA, Nydam DV, Oetzel GR, Overton TR, Ospina PA. Elevated non-esterified fatty acids and β-hydroxybutyrate and their association with transition dairy cow performance: A review. Vet J 2013, 198: 560-570
  59. Jackson DS, Nydam DV, Altier C. Prevalence and risk factors for brucellosis in domestic yak, Bos grunniens, and their herders in a transumant pastoralist system of Dolpo, Nepal. Prev Vet Med. 2014 113(1):47-58
  60. Heins BD, Nydam DV Woolums AR, Berghaus RD, Overton MW. Comparative efficacy of enrofloxacin and tulathromycin for treatment of pre-weaning respiratory disease in dairy heifers. J Dairy Sci. 2014, 97: 372-382
  61. Yasui T, McCann K, Gilbert RO, Nydam DV, Overton TR. Associations of cytological endometritis with energy metabolism and inflammation during the periparturient period and early lactation in dairy cows. J Dairy Sci. 2014, 97: 2763-2770