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Principal Investigator: Dr. Eric Ledbetter
Contact Information: E-mail: ecl32@cornell.edu - Phone: 3-3029
Sponsor: American Society of Veterinary Ophthalmology
Title: Pathogenic Phenotype of Pseudomonas Aeruginosa Isolates from Canine and Equine Ulcerative Keratitis and Normal Extraocular Flora
Annual Direct Cost: $2,000
Project Period: 08/01/2004-07/31/2005
It is the goal of this study to explore the relationship between Pseudomonas aeruginosa pathogenic phenotype and corneal disease in dogs and horses. Specific objectives include: determination of the frequency of each pathogenic phenotype's involvement in ulcerative keratitis and its presence in the normal extraocular flora; assessment of differences in the clinical appearance of corneal infection caused by cytotoxic and invasive strains; correlation of differences in signalment or historical data with a specific phenotype; and comparison of the in vitro antimicrobial susceptibility patterns of cytotoxic and invasive strains in ulcerative keratitis with those of the normal extraocular flora.
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