Advancing the health and well-being of animals and people

Principal Investigator: Rodrigo Bicalho
Co-Principal Investigators: Ynte Schukken, Georgios Oikonomou

Department of Population Medicine and Diagnostic Sciences
Email:; Phone: 607-253-3140
Sponsor: USDA- National Institute of Food and Agriculture (NIFA)
Grant Number: 2013-67015-21233
Title: Dynamics of Milk Microbiota During and After Experimental and Natural Infection with Major Mastitis Pathogens
Project Amount: $499,990
Project Period: 09/01/13-08/31/16

DESCRIPTION (Provided by Applicant): Mastitis is a highly prevalent disease in dairy cows and is arguably the most important one for the dairy industry worldwide, causing economic losses due to reduced milk production, discarded milk, lower probability of conception, premature culling, and treatment cost.

The goal of the proposed project is to conduct basic and applied research to bring new understanding to dairy cow mastitis etiopathogenesis. Specifically, we will use metagenomic sequencing of the 16S rRNA gene, experimental challenge as well as field studies to create unprecedented knowledge regarding the bacterial etiology of bovine mastitis, as well as to evaluate the effects of commonly used antibiotic treatments on mastitic and normal milk microbial communities.

The proposed project will create knew knowledge and we expect obtained results to change our perception of clinical mastitis leading to reevaluation of treatment and prevention strategies. Additionally, a novel diagnostic and prognostic tool for mastitis will be evaluated.