line of dogs standing 

Estimated Breeding Values (EBVs)
for hip and elbow scores

Related Publications

  1. Hou Y, Wang Y, Lu X, Zhang X, Zhao Q, et al. (2013) Monitoring Hip and Elbow Dysplasia Achieved Modest Genetic Improvement of 74 Dog Breeds over 40 Years in USA. PLoS ONE 8(10): e76390, 2013.

  2. Bliss S, Todhunter RJ, Quaas R, et al. Quantitative genetics of traits associated with hip dysplasia in a canine pedigree constructed by mating dysplastic Labrador Retrievers with unaffected Greyhounds. Am J Vet Res 2002;63:1029-1035.

  3. Duan F, Ogden DM, Xu L, Liu K, Lust G, Sandler J, Dykes NL, Zhu L, Zhang Z, Todhunter RJ.  Principal component analysis illustrates separate and related phenotypes for canine hip dysplasia and improves statistical power for association mapping.  J Applied Statistics 40(2):235-251,2013.

  4. Farese JP, Todhunter RJ, Lust G, et al. Dorsolateral subluxation of hip joints in dogs measured in a weight-bearing position with radiography and computed tomography. Vet Surg 1998;27:393-405.

  5. Farese JP, Lust G, Williams AJ, et al. Comparison of measurements of dorsolateral subluxation of the femoral head and maximal passive laxity for evaluation of the coxofemoral joint in dogs. Am J Vet Res 1999;60:1571-1576.

  6. Friedenberg SG, Zhu K, Zhang Z, van den Berg Foels W, Schweitzer PA, Wang W, Fisher PJ, Dykes NL, Corey E, Jung S-W, McDonough SP, Lust G, Bliss SP, Krotscheck U, Gunn TM, Todhunter RJ: A fibrillin 2 haplotype associated with canine hip dysplasia and incipient osteoarthritis.  Am J Vet Res 2011 Apr;72(4):530-40.

  7. Guo G, Zhou Z, Wang Y, Zhao K, Zhu L, Lust G, Hunter L, Friedenberg S, Li J, ZhangY, Harris S, Jones P, Sandler J, Krotscheck U, Todhunter R, Zhang. Canine hip dysplasia is predictable by genotyping. Osteoarthritis Cartilage.  2011 Apr;19(4):420-9. Epub 2011 Jan 5.

  8. Hays L, Zhang Z, Mateescu RG, et al. Quantitative genetics of secondary hip joint osteoarthritis in a Labrador Retriever-Greyhound pedigree. Am J Vet Res 2007;68:35-41.

  9. Liu T, Todhunter RJ, Wu S, et al. A random model for mapping imprinted quantitative trait loci in a structured pedigree: an implication for mapping canine hip dysplasia. Genomics 2007;90:276-284.

  10. Mateescu RG, Zhang Z, Tsai K, et al. Analysis of allele fidelity, polymorphic information content, and density of microsatellites in a genome-wide screening for hip dysplasia in a crossbreed pedigree. J Hered 2005;96:847-853.

  11. Mateescu RG, Burton-Wurster NI, Tsai K, et al. Identification of quantitative trait loci for osteoarthritis of hip joints in dogs. Am J Vet Res 2008;69:1294-1300.

  12. Phavaphutanon J, Mateescu RG, Tsai K, Schweitzer PA, Corey E, Vernier-Singer M, Williams A, Dykes NL, Murphy K, Lust G, Todhunter RJ: Quantitative trait loci for hip dysplasia in the Labrador retriever. Am J Vet Res 70:1094-1101, 2009.

  13. Todhunter RJ, Zachos TA, Gilbert RO, et al. Onset of epiphyseal mineralization and growth plate closure in radiographically normal and dysplastic Labrador retrievers. J Am Vet Med Assoc 1997;210:1458-1462.

  14. Todhunter RJ, Acland GM, Olivier M, et al. An outcrossed canine pedigree for linkage analysis of hip dysplasia. J Hered 1999;90:83-92.

  15. Todhunter RJ, Bertram JE, Smith S, et al. Effect of dorsal hip loading, sedation, and general anesthesia on the dorsolateral subluxation score in dogs. Vet Surg 2003;32:196-205.

  16. Todhunter RJ, Bliss SP, Casella G, et al. Genetic structure of susceptibility traits for hip dysplasia and microsatellite informativeness of an outcrossed canine pedigree. J Hered 2003;94:39-48.

  17. Todhunter RJ, Casella G, Bliss SP, et al. Power of a Labrador Retriever-Greyhound pedigree for linkage analysis of hip dysplasia and osteoarthritis. Am J Vet Res 2003;64:418-424.

  18. Todhunter RJ, Grohn YT, Bliss SP, et al. Evaluation of multiple radiographic predictors of cartilage lesions in the hip joints of eight-month-old dogs. Am J Vet Res 2003;64:1472-1478.

  19. Todhunter RJ, Mateescu R, Lust G, et al. Quantitative trait loci for hip dysplasia in a cross-breed canine pedigree. Mamm Genome 2005;16:720-730.

  20. vandenBerg-Foels WS, Todhunter RJ, Schwager SJ, Reeves AP. 2006. Effect of early postnatal body weight on femoral head ossification onset and hip osteoarthritis in a canine model of developmental dysplasia of the hip. Pediatr Res 60(5):549-554.

  21. Zhang Z, Zhu L, Sandler J, et al. Estimation of heritabilities, genetic correlations, and breeding values of four traits that collectively define hip dysplasia in dogs. Am J Vet Res 2009;70:483-492.

  22. Zhou Z, Sheng X, Zhao K, Zhu L, Guo G, Friedenberg S, Hunter L, Vandenberg-Foels W, Hornbuckle W, Krotscheck U, Corey E, Moise S, Dykes N, Li J, Xu S, Du L, Wang Y, Sandler J, Acland G, Lust G, Zhang Z, Todhunter RJ: Differential Genetic Regulation of Canine Hip Dysplasia and Osteoarthritis. PLoS One 2010 Oct 11;5(10):e13219.

  23. Zhu L, Chen S, Jiang Z, Zhang Z, Hung-Chih K, Xuesong L, McCann M, Harris S, Lust G, Jones P, Todhunter RJ.  Identification of quantitative trait loci for canine hip dysplasia by two sequential multipoint linkage analyses.  Journal of Applied Statistics 39(8), 1710-1731, 2012.

  24. Zhu L, Zhang Z, Feng F, et al. Single nucleotide polymorphisms refine QTL intervals for hip joint laxity in dogs. Anim Genet 2008;39:141-146.

  25. Zhu L, Zhang Z, Friedenberg S, et al. The long (and winding) road to gene discovery for canine hip dysplasia. Vet J 2009;181:97-110.