Infection & Immunity
Research at the College of Veterinary Medicine meets the clinical and research demands of human and animal health. Consistently ranked among the top veterinary colleges in the country, the College leads in scientific discovery. Faculty expertise focuses on the interface between scientific research and clinical practice as well as a commitment to animal and human health.
| Faculty Index |
Faculty |
Area of Interest |
| Limitations of the canine and equine respiratory system in health and disease; Control of breathing in cursorial mammals; Pulmonary immunology in equids; Respiratory system biology in equids |
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Environmental cues of
the intestinal tract that induce virulence gene expression in Salmonella; Defining the genetic pathways by which environmental signals are communicated in Salmonella to cause changes in virulence gene expression; genetic and genomic approaches to characterize this regulon
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Biological interactions that take place between a mother and fetus during pregnancy genes & development; Equine medicine with emphasis on immunology, genetics, and reproduction |
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Parasitic diseases;
Mucosal immunity in the intestinal tract, specifically intestinal immunity expressed against parasitic nematodes
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| Immune cell activation and signaling in development, response to infection and respiratory inflammation |
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| Molecular biology and biochemistry of herpesvirus assembly, envelopment, and cellular exit; Herpesvirus neurovirulence; cell biology of herpesvirus induced changes in cultured cells |
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Parasitic diseases; internal medicine; small animal medicine |
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Dairy production medicine; Bacteriology; prevention and treatment of infection; Antibiotic therapies in livestock |
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| Soil transmitted parasites, parasites of wildlife, visceral larva migrans, host response to soil transmitted pathogens, detection of soil transmitted parasites |
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| Infectious and non-infectious diseases of fish, pathogenesis of important bacterial pathogens of cultured and wild fish, evaluation of new therapeutic compounds for use in cultured food fish |
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Molecular pathogenesis of the infectious bronchitis virus; Ecology and conservation of disease in birds and wildlife |
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| Host intracellular signaling pathways during Toxoplasma infection; role of neutrophils during toxoplasmosis |
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| Molecular basis of antigen-induced immune tolerance, the modulation of the innate immune system response in immunity against cancer, the role of extracellular adenosine in the regulation of central nervous system barrier permeability and gut epithelial barrier permeability |
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Oncogenesis in wild populations, primarily in fish and marine turtles; Eukaryotic gene regulation; oncogenic transformation; viral replication and pathogenesis; toxicology, with special emphasis on viral hemorrhagic septicemia (VHSV) |
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Basic genetics, cell biology, and molecular biology of the
ciliated protozoan Tetrahymena thermophila, application of techniques developed
in this versatile organism to other biologically important protozoa |
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Molecular biology of infectious disease; DNA and recombinant subunit vaccine
development; molecular basis of bacterial pathogenesis; immunopathology of
infectious disease; molecular diagnosis of infectious diseases; host defense
mechanisms; comparative genomics and proteomics |
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Immunology;
Mechanisms of immune evasion;
Tetrahymena as a high-level expression system for vaccine antigens;
Evolution of antigen presentation |
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Examination of how the chemical reactions of biology are organized in time and space, and how this organization is harnessed by cells to generate distinct outcomes; Molecular basis of cell growth and differentiation; Biochemical
and genetic studies of Rab GTPases; Role of Yip family members in membrane
traffic |
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Host intracellular signaling pathways during Toxoplasma infection; role of neutrophils during toxoplasmosis |
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Developmental immunotoxicology; capacity of drugs, environmental chemicals, and dietary factors to produce
persistent immunotoxicologic responses in juvenile and adult offspring following
early life exposure; immune susceptibility to toxicants |
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Equine and bovine internal medicine and critical care; Equine motor neuron disease, equine lyme disease, equine protozoal
myelitis and any advances in internal medicine and critical care for large animals |
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Viral diseases of cattle; Bovine viral diarrhea virus; Viral diseases of dogs; Canine influenza virus; Viral diseases of domestic animals that
impact endangered wildlife; Herd health
program; Biosecurity; effective use of veterinary biologicals |
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Molecular mechanisms of host-parasite
interactions and their relationship to susceptibility or resistance against
enteric bacterial diseases, particularly within the framework of animal models
of colitis |
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Descriptive epidemiology, risk-factor analysis, study design and analysis |
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Equine immune system with specific
interest in immunodeficiencies and
developmental immunity of the foal; immunomodulatory therapies and response to vaccines; comparative animal model for human disease research; Mechanisms of regulation of B cell differentiation using equine bone marrow- and fetal liver-derived hematopoietic stem cells
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Infectious disease and host immune response |
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West Nile Virus; Molecular Diagnostics; Virology; Surveillance Testing
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Small Animal Nephrology, Urology, and gastroenterology; progression of naturally
occurring chronic renal disease; systemic and gastrointestinal effects of uremia in dogs and
cats;
Nutritional and
physiological aspects of uremic anorexia in dogs and cats;
Infectious diseases
as a cause of renal disease in dogs and cats;
Inflammatory bowel disease;
Endocrinology;
Hypercalcemia and the treatment of primary
hyperparathyroidism;
Percutaneous ethanol injection therapy in small animal
medicine |
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| Agricultural Development, Community-based Approaches, International Development (Livestock Diseases And Livestock Production), Public Health, Sustainable Agriculture; poultry testing, consultation and extension services for commercial and backyard poultry producers | |
Basic metabolism in ruminants and genetics; epidemiological and mathematical modeling, genetic analysis and economic methods; food safety; zoonotic infectious diseases; optimizing dairy herd health and management decisions
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Infectious
Diseases, Epidemiology, and Reintroduction Medicine affecting Wildlife Health and Conservation |
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Opthalmology; discovering, identifying, and characterizing ocular infectious diseases |
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Immunology; Innate immunity: Toll-like receptors, signaling, dendritic cells, and controlling microbial infection
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Cell and microbe interactions; facultative intracellular Gram-positive bacterium Listeria monocytogenes |
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Enterobacteriaceae and the microbial ecology of the intestinal tract;
virulence mechanisms and pathogenesis of enteric bacterial infections,
immunity to Salmonella infections;
Salmonella epidemiology and control programs; antimicrobial resistance in
bacteria; development of new diagnostic assays and media for use in veterinary
clinical microbiology; development of biosensors for the rapid detection of
microorganisms |
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Diseases of multiple species, defining epidemiology and risk
factors for diseases;
epidemiology of infectious diseases; quantitative and analytical epidemiology;
veterinary public health and food
safety; production medicine |
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Epidemiological, statistical and mathematical methods to animal disease involving well managed dairy herds; udder health in well-managed dairy herds based on epidemiology and pathobiology |
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Production animal agriculture and public health; infectous calf diseases; herd health and performance |
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Retroviruses; calciviruses; virus structure; virus assembly;
virus-host interactions; oncolytic viruses; virology |
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Virology; Adeno-associated viruses; animal viruses; viral
protein structure; mechanisms of binding to different receptors; how differences
in viral structural proteins can control their host ranges; the processes of
cell infection, and how antibody binding can neutralize the virus in some cases
but not others; biomaterials & drug delivery
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Equine animal medicine; virology; herpesvirus; gastrointestinal diseases |
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| Infectious diseases, vaccinations, T cell production, defects in neonatal T cells, immunology |
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The biology of intracellular infection with emphasis on mycobacteria |
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Identifying strategies for reducing unnecessary
pet euthanasias and enhancing the welfare of companion animals in society using
epidemiologic approaches |
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Epidemiological, statistical and mathematical methods to animal disease involving well managed dairy herds; udder health in well-managed dairy herds based on epidemiology and pathobiology |
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| Biology of intracellular infection by the Chlamydia bacterium |
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Internal Medicine and gastroenterology; role of Helicobacter in gastrointestinal disease; Inflammatory Bowel Disease |
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Molecular evolution and comparative genomics of infectious disease organisms |
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| Duck disease control, good husbandry practices, nutrition, duck production, improvement of diagnostic techniques and the development of new or improved duck biologics. | |
Gastrointestinal and liver diseases of domestic animals, viral hepatitis,
mechanisms of hepatic injury and hepatocarcinogenesis |
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Disease prevention, surveillance, and control programs;
Ruminant and Equine Medicine extension field service |
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| Biology, diagnosis, and epidemiology of parasitic infections in domestic and wild animals |
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Antibody mediated immune mechanisms in infectious disease and vaccination;
allergic diseases; neonatal tolerance and allergy predisposition; strategies to
develop allergy treatments |
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dairy cattle epidemiology; preharvest food safety; Salmonellosis in cattle;
infectious disease |
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| Epidemiological, statistical and mathematical methods to animal disease involving well managed dairy herds | |
Herd Health Management; product evaluation (e.g. milking equipment, diagnostic instruments, therapeutic
compounds, teat dips, and bedding additives); epidemiological modeling; molecular strain typing |
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Virology; Endocytosis of influenza virus; structure-function studies on influenza HA, entry of coronaviruses and rhabdoviruses into host cell; feline infectious peritonitis |
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Herd Health Management; product evaluation (milking equipment, diagnostic instruments, therapeutic
compounds, teat dips, and bedding additives); epidemiological modeling; molecular strain typing
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