Imaging of a nude mouse with a transplanted canine osteosarcoma tumor forming on the right hindleg.  Notice the mottled tissue surrounding the right hindleg along the femur.  This is a cartilgenous/boney tissue being formed by this agressive tumor.  

Advancing the health and well-being of animals and people


Cancer Biology

Research at the College of Veterinary Medicine meets the clinical and research demands of human and animal health. Consistently ranked among the top veterinary colleges in the country, the College leads in scientific discovery. Faculty expertise focuses on the interface between scientific research and clinical practice as well as a commitment to animal and human health.

Faculty Index Faculty A-C Faculty D-L Faculty M-R Faculty S-Z

Faculty
Area of Interest
Ion channel receptor and ligand interactions; NMR and molecular dynamics; molecular neurobiology and biophysics; neurotransmitter receptors and signal transduction

Cell Biology, signal transduction and structural biology

Clinical oncology; efficacy of radiation therapy
Infectious and non-infectious diseases of fish, pathogenesis of retrovirus-caused tumors of fish, pathogenesis of rhabdoviral infections in fish, evaluation of new therapeutic compounds for use in cultured food fish
Molecular basis of antigen induced immune suppression and the modulation of the innate immune system response in immunity against cancer, the role of extracellular adenosine in the regulation of central nervous system barrier permeability and gut epithelial barrier permeability
Anatomic and surgical pathology, diagnostic methods of canine rhabdomyosarcoma and osteosarcoma
Oncogenesis in wild populations, primarily in fish and marine turtles; Eukaryotic gene regulation; oncogenic transformation; viral replication and pathogenesis; toxicology, with special emphasis on viral hemorrhagic septicemia (VHSV)
Understanding the molecular mechanisms by which signals are transmitted from cell surface receptors to biological effectors; identification of new signaling molecules that influence the growth and differentiation of mammalian cells
Genetics and development; Role of the DNA mismatch repair (MMR) family in mammalian meiosis and recombination
Examination of how the chemical reactions of biology are organized in time and space, and how this organization is harnessed by cells to generate distinct outcomes; molecular basis of cell growth and differentiation; biochemical and genetic studies of Rab GTPases; role of Yip family members in membrane traffic
Identification and characterization of genes that are mutated in breast tumors; Reproductive biology; investigation of the role that novel, highly-abundant, and egg-restricted molecules play in reprogramming process; Epigenetic regulation of preimplantation development and embryonic fate decisions
Clinical oncology; ovarian cancer
Jon Erickson
Cell Biology, signal transduction and structural biology
Qiyu Feng
Cell Biology, signal transduction and structural biology 
Small animal medicine; clinical oncology; biomedical imaging
Infectious disease and host immune response
Small animal soft tissue surgery, surgical oncology
Clinical and molecular oncology; cancer genetics; signal transduction
Clinical oncology
Transcriptional and cellular control of tissue morphogenesis; molecular and cellular events that direct the formation of tissues and organs during vertebrate embryogenesis; cell signaling; cellular behaviors and cell shape during development

Immunology; innate immunity: toll-like receptors, signaling, dendritic cells, and controlling microbial infection
Cancer cell biology
Cell biology and enzymology of protein palmitoylation
Clinical oncology; efficacy of radiation therapy
Genetic modeling of human cancer in the mouse; early detection and monitoring of carcinogenesis; neoplasms of reproductive and endocrine systems; Role of stem cell compartment in carcinogenesis, mouse models, stem cell pathology
Ion channel receptor and ligand interactions; NMR and molecular dynamics; molecular neurobiology and biophysics; neurotransmitter receptors and signal transduction
Identification and characterization of stem cells in the adult small intestinal epithelium, focusing on cell surface markers and gene expression by microarray analysis
Mouse genetics and functional genomics; genomic instability; genetic recombination; genetics of gametogenesis and development; use of ES cells to mutagenize the mouse genom
Mechanisms of cancer metastasis and coagulation in thrombosis; Micro and nano-biotechnology; hematopoietic and hemostatic disorders in animals
Gastrointestinal and liver diseases of domestic animals, viral hepatitis, mechanisms of hepatic injury and hepatocarcinogenesis
Clinical Nutrition; Clinical Oncology; Neoplastic Diseases
Genome maintenance mechanisms, cellular responses to genotoxins; mouse cancer models, DNA damage signaling, genomic instability; lung stem cells
cell biology; signal transduction & structural biology
Cell cycle regulation; cell differentiation; myeloblastic hematological tumor cell line, HL-60; Cancer chemoprevention; biomaterials & drug delivery; oncogenes; genetics