Cancer Biology
Research at the College of Veterinary Medicine meets the clinical and research demands of human and animal health. Consistently ranked among the top veterinary colleges in the country, the College leads in scientific discovery. Faculty expertise focuses on the interface between scientific research and clinical practice as well as a commitment to animal and human health.
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Faculty |
Area of Interest |
Ion channel receptor and ligand interactions; NMR and molecular dynamics; molecular
neurobiology and biophysics; neurotransmitter receptors and signal transduction |
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Cell Biology, signal transduction and structural biology |
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Clinical oncology; efficacy of radiation therapy |
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Infectious and non-infectious diseases of fish, pathogenesis of retrovirus-caused tumors of fish, pathogenesis of rhabdoviral infections in fish, evaluation of new therapeutic compounds for use in cultured food fish |
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Molecular basis of antigen induced immune suppression and the modulation of the innate immune system response in immunity against cancer,
the role of extracellular adenosine in the regulation of central nervous system barrier permeability and gut epithelial barrier permeability
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| Anatomic and surgical pathology, diagnostic methods of canine rhabdomyosarcoma and osteosarcoma |
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Oncogenesis in wild populations, primarily in fish and marine turtles; Eukaryotic gene regulation; oncogenic transformation; viral replication and pathogenesis; toxicology, with special emphasis on viral hemorrhagic septicemia (VHSV) |
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Understanding the molecular mechanisms by which signals are transmitted from cell surface receptors to biological effectors; identification of new signaling molecules that influence the growth and differentiation of mammalian cells |
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Genetics and development; Role of the DNA mismatch repair
(MMR) family in mammalian meiosis and recombination
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Examination of how the chemical reactions of biology are organized in time and space, and how this organization is harnessed by cells to generate distinct outcomes; molecular basis of cell growth and differentiation; biochemical
and genetic studies of Rab GTPases; role of Yip family members in membrane
traffic |
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Identification and characterization of
genes that are mutated in breast tumors; Reproductive biology; investigation of the role that novel, highly-abundant, and egg-restricted molecules
play in reprogramming process; Epigenetic regulation of preimplantation development and embryonic fate
decisions |
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Clinical oncology; ovarian cancer |
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Cell Biology, signal transduction and structural biology |
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Cell Biology, signal transduction and structural biology |
Small animal medicine; clinical oncology; biomedical
imaging
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Infectious disease and host immune response |
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Small animal soft tissue surgery, surgical oncology |
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Clinical and molecular oncology; cancer genetics; signal transduction |
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Clinical oncology |
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Transcriptional and cellular control of tissue morphogenesis; molecular and cellular events that direct the formation of tissues and organs
during vertebrate embryogenesis; cell signaling;
cellular behaviors and cell shape during development |
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Immunology; innate immunity:
toll-like receptors, signaling, dendritic cells, and controlling microbial
infection
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Cancer cell biology |
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Cell biology and enzymology of protein palmitoylation
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Clinical oncology; efficacy of radiation therapy |
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| Genetic modeling of human cancer in the mouse; early detection and monitoring of
carcinogenesis; neoplasms of reproductive and endocrine systems; Role of stem cell compartment in carcinogenesis, mouse models, stem cell
pathology
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Ion channel receptor and ligand interactions; NMR and molecular dynamics; molecular
neurobiology and biophysics; neurotransmitter receptors and signal transduction |
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Identification and characterization of stem cells in the adult small intestinal epithelium, focusing on cell surface markers and gene expression by microarray analysis |
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Mouse genetics and functional genomics; genomic instability; genetic
recombination; genetics of gametogenesis and development; use of ES cells to
mutagenize the mouse genom |
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Mechanisms of cancer metastasis and coagulation in thrombosis; Micro and nano-biotechnology; hematopoietic and hemostatic disorders in animals |
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Gastrointestinal and liver diseases of domestic animals, viral hepatitis,
mechanisms of hepatic injury and hepatocarcinogenesis |
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Clinical Nutrition; Clinical Oncology; Neoplastic Diseases |
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Genome maintenance mechanisms, cellular responses to genotoxins; mouse cancer models, DNA damage signaling, genomic instability; lung stem cells |
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cell biology; signal transduction & structural biology |
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Cell cycle regulation; cell differentiation; myeloblastic hematological tumor cell line, HL-60; Cancer chemoprevention; biomaterials & drug delivery;
oncogenes; genetics |
