Anatomy of a Lab: Danko
Dr. Charles Danko’s group thinks of a cell’s genome as a software program, turning on and off different genes to accomplish cellular functions. To better understand how that software operates, they merge two approaches – computational biology and molecular biology techniques, such as ChRO-seq, a highly accurate method to detect gene expression developed in their lab. Ultimately, they aim to understand how variations in the software code explain the evolution of new species and to “debug” that code to find how certain changes lead to cancer.
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