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Latasha Ludwig, DVM, PhD, DACVP

Assistant Clinical Professor

Department of Population Medicine and Diagnostic Sciences

Anatomic Pathology

Cornell University College of Veterinary Medicine
Ithaca, NY 14853
lal269@cornell.edu

Profile

Research/Clinical Interests

  • Investigation of miRNAs in circulation and in situ of multiple canine neoplasms.
    • Focus on canine osteosarcoma, lymphoma, and splenic masses.
  • Investigation of the mutational landscape of canine and feline tumors (collaboration with the Wellcome Trust Sanger Institute, Cambridge, UK).
  • Immunohistochemistry in canine and feline neoplasms. 

Education

  • Ph.D, Pathobiology, Ontario Veterinary College, University of Guelph, 2024
  • Diplomate of the American College of Veterinary Pathologists, 2023
  • DVM, Ontario Veterinary College, University of Guelph, 2019

Biography/Professional Experience

  • 2024-2025: Scientific Advisory Board, Morris Animal Foundation
  • 2020-2024: Companion Animal Tumour Sample Bank Quality Control Assessor, Health Sciences Centre, Ontario Veterinary College, University of Guelph
  • 2019-2024: PhD Candidate Anatomic Pathology, Department of Pathobiology, Ontario Veterinary College, University of Guelph

Awards and Honors

  • Governor General of Canada’s Academic Medal - Gold (University of Guelph), 2025
  • Veterinary Pathology Editors’ Award for an Observational Study, 2025
  • Davis Thompson Foundation Trainee Scholarship Award, 2023
  • Vanier Canadian Graduate Scholarship (NSERC), 2020
  • Ontario Veterinary College Fellowship, 2020

Professional/Academic Affiliations

American College of Veterinary Pathologists

Publications

Selected Publications

  1. Ludwig L, Treleaven H, Moorehead R, Foster RA, Ali RA, Wood RD, Wood GA. Differential expression of miRNAs in primary canine appendicular osteosarcoma tissue and pulmonary metastases. Vet Pathol. 2025 Sep 17;:3009858251356603. doi: 10.1177/03009858251356603. [Epub ahead of print] PubMed PMID: 40963183.
  2. Ludwig L, Treleaven H, Moorehead R, Foster RA, Wood RD, Ali RA, Wood GA. Classification and Prognostication of B-Cell and T-Cell Multicentric Lymphoma in Dogs Using Serum MicroRNAs. Vet Comp Oncol. 2025 Jun;23(2):310-319. doi: 10.1111/vco.13057. Epub 2025 Apr 5. PubMed PMID: 40186510; PubMed Central PMCID: PMC12082750.
  3. Ludwig L, Treleaven H, Khachadoorian A, Degasperi B, Walter I, Stuart D, Foster RA, Wood RD, Ali RA, Wood GA. MicroRNAs in serum and tissue can differentiate splenic hemangiosarcoma from other splenic masses in dogs. Vet Pathol. 2025 Sep;62(5):659-671. doi: 10.1177/03009858251317466. Epub 2025 Feb 19. PubMed PMID: 39968796; PubMed Central PMCID: PMC12314205.
  4. Ludwig L, Vanderboon EN, Treleaven H, Wood RD, Schott CR, Wood GA. Patient-matched tumours, plasma, and cell lines reveal tumour microenvironment- and cell culture-specific microRNAs. Biol Open. 2024 Dec 15;13(12). doi: 10.1242/bio.060483. Epub 2024 Dec 23. PubMed PMID: 39714200; PubMed Central PMCID: PMC11695573.
  5. Ludwig L, Rätsep E, Fontenot D, Conley KJ, Rodriguez CE, Larouche CB. Head tilt in 6 Ankole-Watusi cattle (Bos taurus ankole) with chronic exudative cornual sinusitis. Vet Pathol. 2025 Mar;62(2):248-253. doi: 10.1177/03009858241295396. Epub 2024 Nov 8. PubMed PMID: 39513515; PubMed Central PMCID: PMC11874580.
  6. Rätsep E, Ludwig L, Dobromylskyj M. Orofacial masses in domestic rabbits: a retrospective review of 120 cases from 2 institutions, 2000-2023. J Vet Diagn Invest. 2024 Sep;36(5):724-729. doi: 10.1177/10406387241234326. Epub 2024 Feb 22. PubMed PMID: 38389410; PubMed Central PMCID: PMC11462579.
  7. Ludwig L, Edson M, Treleaven H, Viloria-Petit AM, Mutsaers AJ, Moorehead R, Foster RA, Ali A, Wood RD, Wood GA. Plasma microRNA signatures predict prognosis in canine osteosarcoma patients. PLoS One. 2024;19(12):e0311104. doi: 10.1371/journal.pone.0311104. eCollection 2024. PubMed PMID: 39739708; PubMed Central PMCID: PMC11687810.
  8. Wong K, Abascal F, Ludwig L, Aupperle-Lellbach H, Grassinger J, Wright CW, Allison SJ, Pinder E, Phillips RM, Romero LP, Gal A, Roady PJ, Pires I, Guscetti F, Munday JS, Peleteiro MC, Pinto CA, Carvalho T, Cota J, Du Plessis EC, Constantino-Casas F, Plog S, Moe L, de Brot S, Bemelmans I, Amorim RL, Georgy SR, Prada J, Del Pozo J, Heimann M, de Carvalho Nunes L, Simola O, Pazzi P, Steyl J, Ubukata R, Vajdovich P, Priestnall SL, Suárez-Bonnet A, Roperto F, Millanta F, Palmieri C, Ortiz AL, Barros CSL, Gava A, Söderström ME, O'Donnell M, Klopfleisch R, Manrique-Rincón A, Martincorena I, Ferreira I, Arends MJ, Wood GA, Adams DJ, van der Weyden L. Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer. Genome Biol. 2023 Aug 28;24(1):191. doi: 10.1186/s13059-023-03026-4. PubMed PMID: 37635261; PubMed Central PMCID: PMC10464500.
  9. Ludwig L, Dobromylskyj M, Wood GA, van der Weyden L. Feline Oncogenomics: What Do We Know about the Genetics of Cancer in Domestic Cats?. Vet Sci. 2022 Oct 4;9(10). doi: 10.3390/vetsci9100547. Review. PubMed PMID: 36288160; PubMed Central PMCID: PMC9609674.
  10. Ludwig L, Husnik R, Rätsep E, Beeler-Marfisi J, Stalker M, Wood GA, Woods JP. Unilateral primary carcinoma of the kidney with central nervous system invasion and vertebral lysis in a cat. JFMS Open Rep. 2022 Jul-Dec;8(2):20551169221141319. doi: 10.1177/20551169221141319. eCollection 2022 Jul-Dec. PubMed PMID: 36601445; PubMed Central PMCID: PMC9806377.
  11. Wong K, Ludwig L, Krijgsman O, Adams DJ, Wood GA, van der Weyden L. Comparison of the oncogenomic landscape of canine and feline hemangiosarcoma shows novel parallels with human angiosarcoma. Dis Model Mech. 2021 Jul 1;14(7). doi: 10.1242/dmm.049044. Epub 2021 Jul 23. PubMed PMID: 34296746; PubMed Central PMCID: PMC8319545.

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